生物反馈疗法治疗出口梗阻型便秘38例临床分析

为探讨生物反馈疗法对出口梗阻型便秘（OOC）患者的临床疗效,对符合罗马Ⅲ标准并经直肠肛管压力测定、表面肌电评估诊断为以盆底功能紊乱为主要特征的38例OOC患者进行生物反馈治疗。结果显示,38例患者经生物反馈治疗后,临床症状和肛管肌电图均得到极大改善,有效率分别为84．21％（32／38）和71．05％（27／38）;且生物反馈治疗疗效与患者年龄及性别呈直线相关性（P〈0．05）。结果表明,生物反馈疗法是治疗OOC的有效方法。     

吻合器痔上黏膜环切钉合术治疗出口梗阻型便秘心理与生物动力学分析

目的探讨出口梗阻型便秘可能的发病机制,为PPH手术治疗出口梗阻型便秘寻找理论依据。方法19例诊断为出口梗阻型便秘的患者为病例组．同时选择9例健康志愿者作为对照组。患者手术前后以及对照组均接受抑郁汉密尔顿抑郁量表（HAMD）、汉密尔顿焦虑量表（HAMA）和肛门直肠动力学检测。结果各组肛管功能长度的差异无统计学意义（P=0．41）;病例组术后15d最低感知阈值、最大耐受阈值、直肠排粪阈值均明显低于术前及对照组（P〈0．05）。术后90d最低感知阈值、最大耐受阈值、直肠排粪阈值显著回升。精神评价方面,HAMA及HAMD总分术后均呈现先降后升的改变。结论出口梗阻性便秘患者存在肛门直肠动力学障碍和精神心理障碍．PPH手术治疗可改善上述情况。     

多部位生物反馈疗法治疗耻骨直肠肌失弛缓型便秘的临床疗效观察

为探讨对肛管高压区、耻骨直肠肌及直肠下段三个部位进行生物反馈电刺激治疗耻骨直肠肌失弛缓型便秘的临床疗效,我们对42例耻骨直肠肌失弛缓型便秘患者采用此生物反馈疗法治疗,电刺激模式：20min／次,3次／d,15次／周,均治疗2周。结果显示,随访3个月,患者排便症状改善情况：显效9例,有效27例,无效6例,总有效率85．71％（36／42）。患者的排便频率、排便时间、排便用力程度、肛门及骶后疼痛在治疗结束时、3个月随访时与治疗前相比改善均非常显著（P〈0．01）;粪便性状在治疗结束时、3个月随访时与治疗前相比改善显著（P〈0．05）。患者治疗结束时肛管静息压、括约肌功能长度、直肠阈感觉容量较治疗前均明显改善,差异有显著性意义（P〈0.01）;肛管最大收缩压、直肠最大耐受量较治疗前改善显著（P〈0．05）。结果表明,精确肛管高压区、耻骨直肠肌及直肠下段三个部位进行生物反馈电刺激治疗能有效地治疗耻骨直肠肌失弛缓型便秘。     

生物反馈联合聚乙二醇口服治疗出口梗阻型便秘32例临床观察

为探讨生物反馈联合药物疗法治疗出口梗阻型便秘（OOC）的疗效,对32例OOC患者进行生物反馈训练治疗,每次20～30min。每周5次,同时予聚乙二醇4000散剂口服,每次10g,2次／d。2周为一疗程,治疗2个疗程。随访3个月对治疗前后患者排便改善情况、便秘积分结果、肛门直肠测压结果进行对比分析。结果显示,32例患者中,显效11例,有效14例,无效7例,总有效率78．12％。治疗后,患者排便频率、排便时间、粪便性状、排便用力程度、排便不尽感评分较治疗前均明显下降;且直肠肛门抑制反射的最小松弛容积、肛管静息压、仞始便意、最大耐受量各值均较治疗前下降,最大缩榨压明显提高。结果表明,生物反馈联合聚乙二醇4000散剂口服能有效地改善OOC患者的排便困难症状。     

肛管直肠环V形切除术治疗出口梗阻型便秘48例

为探讨治疗出口梗阻型便秘的疗效,对48例因肛管商肠环肥大、僵硬而导致的山口梗阻型便秘患者,均采用肛管直肠环V形切除术．主要切除肌管直肠环肥大、俺硬、管腔狭窄部,切除肛管直肠环的前后直径1/2或1／3,左右间距1．5～2．0cm．要边切边缝合,确保肛管直肠环的相互连续性。结果显示,48例均恢复排便顺应性,肛管直肠环弹性良好,肛门自制功能正常．随游巾无复发病例。结果表明．肛管直肠环V形切除术治疗肛管直肠环肥大、僵硬导致的出口梗阻型便秘疗效肯定。     

挂线治疗出口梗阻型便秘30例临床观察

为探讨挂线疗法治疗出口梗姐型便秘的疗效．将55例因耻骨直肠肌痉挛引起的出口梗阻型便秘的病人分为两组。采用挂线30例（治疗组）,采用部分耻骨直肠肌切断术25例（对照组）。结果显示,治疗组30例均恢复排便顺应性,肛门指诊肛管直肠弹性良好,肛门自制功能正常,术后疼痛径,往院时间、创面愈合时间均短,无术后感染,复发率低．明显优于对照组（P〈0.01）。结果表明,挂线术治疗出口梗阻型便秘,具有术式简单、术后疼痛轻、住院时间短、复发率低等优点。     

盆底生物反馈疗法加针刺八谬穴治疗盆底失弛缓综合征所致便秘的临床疗效

为探讨盆底生物反馈疗法加针刺八髂穴治疗盆底失弛缓综合征所致便秘的临床疗效,将60例盆底失弛缓综合征所致的便秘患者随机分为治疗组和对照组,各30例,治疗组给予盆底生物反馈治疗加针刺八露穴,对照组单纯给予生物反馈疗法治疗。比较两组患者治疗后排便情况、肛门测压情况及总体疗效。结果显示,两组患者治疗前排便情况各指标评分及肛门测压结果比较,差异均无统计学意义,P〉0．05。治疗后两组患者排便周期、排便时间、排便方式、排便不尽感、肛门坠胀感、便质方面评分及肛管静息压、肛管最大缩榨压、直肠初始感觉阈值、直肠最大耐受阈值均下降,其中治疗组各指标下降更明显,P〈0．05或P〈0．01或P〈0．001。治疗组总有效率明显高于对照组,P〈0．05。结果表明,盆底生物反馈疗法加针刺八髂穴治疗盆底失弛缓综合征所致便秘简便易行,效果显著。     

小针刀结合生物反馈疗法治疗耻骨直肠肌综合征所致便秘的临床观察

为探索小针刀结合生物反馈疗法治疗耻骨直肠肌综合征所致便秘的有效性,将耻骨直肠肌综合征所致便秘的患者70例分为研究组（37例）和对照组（33例）。研究组采用小针刀结合生物反馈疗法治疗,对照组采用单纯生物反馈疗法治疗,疗程均为20d。结果显示,研究组疗效（总有效率91．9％）显著优于对照组（总有效率66．7％）。结果表明,小针刀结合生物反馈疗法是治疗耻骨直肠肌综合征所致便秘的有效方法。     

生物反馈疗法治疗慢性功能性便秘30例

目的：观察生物反馈治疗功能性便秘的疗效。方法：对30例慢性功能性便秘患者进行生物反馈治疗10～30次,观察治疗前后排便情况,进行直肠肛管测压及结肠传输试验并作对比分析。结果：30例中有效23例,钡条排出率由治疗前的平均18.53％增至61.7l％（P＜0.05）,肛门一直肠抑制反射、直肠感觉阈值及直肠最大耐受阈值下降（P＜0.05）。结论：生物反馈治疗各种类型的功能性便秘,可能有一定疗效。     

痔上黏膜环切术治疗直肠前突所致出口梗阻型便秘的疗效观察

目的探讨痔上黏膜环切术(PPH)治疗中重度直肠前突所引起的梗阻型便秘的临床疗效。方法 对48例中重度直肠前突患者采用痔上黏膜环切术治疗,随访4~6个月,对比分析手术前后肛管直肠测压参数。结果患者术后每天1~2次软便,自觉排便梗阻感明显缓解,手术前后患者直肠静息压、肛管静息压、各项感觉阈值变化差异均无统计学意义(P0.05),直肠力排压与肛管舒张压力值降低差异有统计学意义(P0.05)。结论 PPH术是一种治疗直肠前突所致出口梗阻型便秘的有效方法 。     

生物反馈治疗功能性排便障碍型便秘41例临床疗效观察

目的探讨生物反馈治疗功能性排便障碍型便秘的临床疗效。方法对41例符合功能性排便障碍型便秘的患者进行生物反馈治疗,每次60min,每周1次,4次一个疗程,完成10次以上生物反馈治疗后进行疗效评估。结果 41例患者在肛管、直肠静息压,直肠最大收缩压,初始排便感等方面较治疗前均有明显改善(P0.05);排便Cleveland便秘评分较治疗前显著降低(P0.05)。41例患者中治愈21例,显效7例,有效2例,无效11例,总有效率73.17%。结论生物反馈疗法治疗功能性排便障碍型便秘有较好的疗效。     

生物反馈结合心理疏导治疗功能性肛门直肠痛的临床研究

目的研究生物反馈结合心理疏导对功能性肛门直肠痛患者的临床症状、精神状态及生活质量的影响。方法选取功能性肛门直肠痛患者17例,对每名患者进行10次(以上)生物反馈治疗,并在治疗过程中予以适当心理疏导,应用疼痛VAS卡、焦虑自评量表(SAS)、抑郁自评量表(SDS)及简明健康调查量表(SF-36)评估患者治疗前后的临床症状、精神状态及生活质量的变化。结果疼痛明显好转,痊愈2例(11.76%),显效7例(41.18%),有效8例(47.06%)。患者焦虑、抑郁积分较治疗前显著降低(P0.05),SF-36得分在生理机能、躯体疼痛、一般健康、情感职能、精神健康、社会功能及精力7个维度积分明显增加(P0.05)。结论生物反馈结合心理疏导能够改善患者功能性肛门直肠痛症状,缓解焦虑和抑郁的情绪,提高生活质量。     

Treatment strategies for chronic constipation: our experience

Outlet dysfunction is responsible for 25% of all cases of chronic constipation. The aim of this article was to report our outcomes and investigate the efficacy of the different treatments that we have adopted to solve it. One hundred and twenty-six patients were treated with either surgery and/or biofeedback therapy. Ninety-seven of the 126 patients underwent surgery; 48 with hidden rectal prolapse: 44 underwent a stapled transanal rectal resection using a double stapler PPH-01 and 4 a single stapler PPH-01; 31 with rectocele and 18 with both hidden rectal prolapse and rectocele, respectively, underwent a stapled transanal rectal resection using a double stapler PPH-01. Thirteen of 97 patients showing outlet dysfunction in spite of surgery progressed to biofeedback therapy. 29 of the 126 patients were treated with biofeedback training only. Surgery helped 51.6% of treated for rectocele, 75% of those treated for hidden rectal prolapse, and 78% of patients treated for both rectocele and hidden rectal prolapse, respectively. Approximately 80% of patients treated with biofeedback alone and 67.8% of those treated with both surgery and biofeedback reported an improvement, respectively. Treatment of the outlet dysfunction can be difficult. The therapeutic option chosen for each subject in spite of a careful functional patient examination may not prove to be the most appropriate one. Our experience suggests that the surgery of the obstructed defecation could achieve better outcomes if a course of biofeedback therapy precedes it, above all in patients with both organic and functional disorders, and the repair of rectocele with stapled transanal rectal resection fails to resolve the outlet dysfunction in several cases.     

The role of biofeedback therapy in functional proctologic disorders.

BACKGROUND AND AIMS: The question which patients with functional proctologic disorders truly benefit from the biofeedback has not been equivocally resolved. The aim of this study was to assess our results of biofeedback therapy in patients with anal incontinence or constipation. MATERIAL AND METHODS: Fifty-two consecutive patients who were treated with biofeedback therapy between January 1998 and March 2002 were studied. Data was collected from our proctologic database. RESULTS: Of the twenty-two patients with anal incontinence who underwent biofeedback therapy during the study period, twenty patients had incontinence affecting quality of life. Twelve patients (60 percent) benefited from biofeedback as judged by improvement of incontinence symptoms affecting quality of life; all four patients with partial sphincter defects, three out of four patients after secondary repair, three out of five patients with persistent incontinence after rectal prolapse surgery and two out of seven patients having idiopathic incontinence. Of the thirty patients who underwent biofeedback therapy for constipation, twenty-five had intractable symptoms of constipation. Constipation resolved in sixteen patients (64 percent); in thirteen out of nineteen (68 percent) of those with pelvic floor dysfunction (PFD) and in three out of six (50 percent) having combined PFD and slow transit constipation. In patients with PFD constipation was resolved in ten out of thirteen patients (77 percent) with anismus but in only three out of six (50 percent) having other causes. CONCLUSIONS: Biofeedback therapy improves incontinence after sphincter repairs and in patients with partial external sphincter defects, but does not improve idiopathic incontinence. Biofeedback is also effective in patients with constipation, especially when anismus is the only cause for symptoms of constipation and difficult evacuation.     

结肠切除直肠悬吊盆底抬高重建术治疗重度混合型便秘的临床分析（附16例报告）

目的探讨结肠慢传输型便秘（STC）合并出口梗阻型便秘（OOC）的外科治疗方法及疗效。方法总结16例混合型便秘手术及随访资料。13例行结肠次全切除逆蠕动盲直吻合＋直肠悬吊、盆底抬高重建术,3例行结肠全切除回直吻合术＋直肠及子宫悬吊、盆底抬高重建术。结果术后无严重并发症,1例患者发生粘连性小肠梗阻。随访1～3年,每天大便次数为2～4次,Wexner失禁评分（4.8±1.6）。7例患者对手术效果满意,9例非常满意。结论结肠（次）全切除、直肠悬吊、盆底抬高重建术是治疗混合型便秘的有效方法。