1例残肢痛伴幻肢痛药物治疗方案分析

目的 探讨药学监护在1例残肢痛伴幻肢痛药物治疗过程中的作用。方法 对患者治疗方案运用循证药学的思维进行讨论,并对该患者具体用药进行分析。结果 采用卡马西平、非甾体抗炎药用于幻肢痛治疗不合理。结论 循证药学临床思维在患者用药治疗过程中可以发挥重要作用,有助于提高临床药师的药学服务水平,促进合理用药。     

Acupressure may offer some pain relief in labour pain

Hjelmstedt A, Shenoy ST, Stener‐Victorin E, Lekander M, Bhat M, Balakumaran L, Waldenstrom U. Acupressure to reduce labor pain: a randomized controlled trial. Acta Obstet Gynecol 2010; 89: 1453–9.     

Mechanisms of neuropathic pain

Neuropathic pain is a disease of global burden. Its symptoms include spontaneous and stimulus-evoked painful sensations. Several maladaptive mechanisms underlying these symptoms have been elucidated in recent years: peripheral sensitization of nociception, abnormal excitability of afferent neurons, central sensitization comprising pronociceptive facilitation, disinhibition of nociception and central reorganization processes, and sympathetically maintained pain. This review aims to illustrate these pathophysiological principles, focussing on molecular and neurophysiological findings. Finally therapeutic options based on these findings are discussed.     

血液稀释与灯盏花素联合治疗脑梗死的临床观察

我院自１９９７年１月～１９９９年１０月 ,应用血液稀释疗法与灯盏花素联合治疗脑梗死取得了较满意的效果 ,现报道如下 :１资料与方法１ １一般资料 :血液稀释加灯盏花素治疗组５８例 ,男３０例 ,女２８例。合并冠心病１９例 ,糖尿病８例 ,高血压１０例 ,年龄４３岁～７９岁 ,平均６１岁。对照组７４例 ,男３９例 ,女３５例 ,平均６０岁。两组病例均根据第二届全国脑血管病会议拟定的诊断标准 ,并做脑ＣＴ检查确诊 ,两组患者治疗前 ,年龄、病程和神经功能平均积分经统计学处理 ,Ｐ＞０ ０５ ,无明显差异。１ ２治疗方法 :治疗组用血液稀释…