氟保护漆防龋效果观察

目的：观察氟保护漆的防龋效果及学生接受程度。方法：将1666名8－9岁学生分三组进行了一年半的观察，比较各组的患龋率、龋均及新生龋情况．调查并观察学生反应。结果：乳牙新生龋降低率为70．0％，恒牙新生龋降低率为82．4％，且无不良反应。结论：氟保护漆不但防龋效果好，而且操作简便，不易引起交叉感染，无不良反应，学生易于接受。     

氟保护漆在第一恒磨牙龋病预防中的效果评估

目的 观察氟保护漆预防第一恒磨牙龋病的临床效果。 方法 选取600名6～8岁的儿童计2 400颗牙齿进入2部分试验,采取自身对照方法分别接受空白对照、氟保护漆;氟保护漆及窝沟封闭处理,于6、12、18、24个月观察并两两比较分析龋病发病率及2年各组患龋率情况。 结果 第一部分研究结果显示各个时间氟保护漆组比空白对照组具有更低的龋病发病率,经统计学分析,12、18、24个月的龋病发病率及2年的患龋率2组差异有统计学意义(P<0.05)。第二部分结果显示:各个时间段氟保护漆组比窝沟封闭组均具有略高的龋病发病率,但2组龋病发病率及患龋率差异无统计学意义。 结论 氟保护漆有较好的龋病预防效果,可考虑在临床上推广应用。     

3岁儿童使用氟保护漆后尿氟近期变化的研究

【目的】了解3岁儿童口腔局部应用氟保护漆对机体氟化物水平的影响。【方法】采用氟离子选择电极法,分别于实验前24 h,实验后244、8 h对10名使用0.5%氟保护漆的儿童,5名使用0.5%氟化钠的儿童,5名使用空白对照剂的儿童的尿氟进行测定分析。【结果】各组间尿氟含量差异无显著性(P>0.05),组内不同时间上的尿氟浓度差异也无显著性(P>0.05)。【结论】儿童口腔局部应用氟保护漆后,不会影响机体氟化物水平,氟保护漆是一种安全的局部防龋药物。     

氟保护漆结合窝沟封闭剂预防儿童龋齿效果的临床效果研究

目的?对氟保护漆结合窝沟封闭剂预防儿童龋齿效果的临床效果进行研究.方法?将我市某一所幼稚园的120名3~4岁儿童随机平均分成两组,即干预组(60例)和对照组(60例).其中干预组使用0.5%氟保护漆、0.1氟保护漆、0.5%氟化纳结合窝沟封闭剂预防龋齿治疗的方法,而对照组只做日常刷牙等口腔护理的方法.结果?一年后观察组的儿童患上龋齿的概率平均数据明显比对照组的低.结论?氟保护漆结合窝沟封闭剂预防儿童龋齿的效果显著明显.     

氟保护漆预防学龄前儿童乳牙龋的疗效观察

目的 观察氟保护漆预防乳牙龋病的效果,为本区全面开展学龄前儿童涂氟防龋提供依据。方法 选择本区试点幼儿园中班儿童涂布氟保护漆,每半年1次,连续2年共涂布4次,观察涂氟组和对照组患龋率、新增龋均的情况。结果 2年后,对照组的患龋率、新增龋均显著高于涂氟组(P<0.05)。结论 学龄前儿童集体涂布氟保护漆能有效预防乳牙龋的发生、发展。     

一次性含氟窝沟封闭剂和氟保护漆预防儿童恒牙龋病的效果对比分析

目的 比较儿童恒牙龋病预防中一次性含氟窝沟封闭剂和氟保护漆两种方案的效果及成本.方法 选取2017年1月-2018年3月某地区4个学校15个班的120名7～8岁儿童为研究对象,根据性别、年龄、生活环境等基本资料,组间均衡可比的原则分为窝沟封闭组、氟保护漆组,每组60例.窝沟封闭组儿童使用一次性含氟窝沟封闭剂,氟保护漆组...     

集体儿童涂氟保护漆预防龋齿的效果分析

目的:在集体儿童口腔保健中,探索涂氟保护漆对龋齿的预防效果及临床意义。方法:随机抽取1 309人次3～5岁幼儿园的儿童作为实验组,831人次同年龄儿童作为对照组。对实验组每名儿童的每颗牙齿涂氟保护漆每年涂1次,对照组不做任何预防措施。结果:2年后平均患龋率呈逐年下降的趋势,两组的患龋率有极显著性差异。结论:在托幼园所开展涂氟保护漆能有效地降低口腔患龋,是集体儿童口腔保健的有效措施,从而促进儿童健康。     

氟保护漆预防儿童龋齿的临床效果评价

目的评价使用氟保护漆预防儿童乳牙龋病的疗效。方法对幼儿园3～6岁儿童用氟保护漆涂擦牙面,半年后重复涂擦1次,1年后检查试验组和对照组乳牙患龋情况,并对试验前后进行比较。结果试验组患龋率、龋齿平均发病率明显低于对照组,2组之间存在显著性差异(P<0.01);试验组新增龋病发病率、新增乳牙龋均明显低于对照组。发病率2组之间存在显著性差异(P<0.01)。结论氟保护漆对儿童乳牙龋病的预防是有效的。     

氟保护漆预防龋齿研究进展

<正>龋病是一种严重影响人类口腔健康的常见病和多发病,20世纪,口腔医学界发现了氟化物能够预防龋病,经过几十年的探索、研究,氟化物防龋技术得到了WHO和许多国家的权威机构推荐,得以在世界范围内广泛应用。在众多的局部氟防龋措施中,氟保护漆以其实用、有效、安全,易于操作,病人易于接受等优点,在我国得到越来越多的关注和应用,本文对氟保护漆进行综述。     

氟化泡沫与氟保护漆对离体乳牙釉质保护效果的比较

目的 比较局部使用氟化泡沫和氟保护漆对乳牙釉质脱矿的保护作用。方法 60颗牙冠完整的下颌乳切牙,在牙冠唇侧选定釉质处理区域,按照不同试剂处理分为A、B、C三组,A:氟化泡沫组,B:氟保护漆组,C:去离子水组。处理后的离体牙在脱矿液中浸泡72 h后用扫描电镜观察釉质表面形态结构差异;利用原子吸收分光光度计检测各组脱矿液中钙离子的溶出量。结果 A、B两组析出的Ca²⁺浓度均显著低于C组(P<0.05);B组析出的Ca²⁺浓度显著低于A组(P<0.05)。扫描电镜观察釉质表面显示C组较A、B两组脱矿明显,A、B两组的釉质表面可见再矿化物。结论 离体下颌乳切牙应用氟化泡沫及氟保护漆都可以增强其釉质的抗酸能力并促进再矿化,氟保护漆较氟化泡沫具有更强的保护作用。     

氟元素对人体健康的影响

氟是人体必需的微量元素之一,对生长发育、骨骼代谢等都有重要的影响。人体摄入适量的氟有益于身体健康,但摄氟过量会导致氟中毒,缺氟又会引起多种生理和病理变化。分析了氟与人体健康的关系,并提出了一些预防氟危害的措施。     

An Observational Study of the Association of Fluoride Varnish Applied During Well Child Visits and the Prevention of Early Childhood Caries in American Indian Children

Objectives To determine if fluoride varnish applied at well child care visits would decrease the prevalence of dental caries in a group of American Indian children at high risk for early childhood caries. Methods This was an observational study in an American Indian community. Starting in 2002 all children received fluoride varnish applications at well child care visits at 9, 12, 15, 18, 24 and 30 months. The Head Start class of 2003 served as historical controls and students in 2004 and 2005 had increasing number of fluoride varnish treatments. All children entering Head Start from 2003 to 2005 had dental exams to determine the number of decayed, missing and filled surfaces (dmfs) present. The number of dmfs for each child was correlated with the number of fluoride varnish treatments received. Results Children with 4 or more treatments had 15.5 dmfs (95%CI 10.8–20.4) versus children with no fluoride varnish treatments who had 23.6 dmfs (95%CI 19.5–25.8) for a 35% decrease in overall caries. Children who received 1, 2 or 3 treatments showed no significant difference in dmfs when compared with children who had no fluoride varnish applications. Conclusions Fluoride varnish applied at well child care visits can reduce early childhood caries in American Indian children. Consideration should be given to making fluoride varnish more available to American Indian and Alaska Native children at well child visits. These findings may be applicable to other children who are at increased risk for early childhood caries.     

An Observational Study of the Association of Fluoride Varnish Applied During Well Child Visits and the Prevention of Early Childhood Caries in American Indian Children

Objectives To determine if fluoride varnish applied at well child care visits would decrease the prevalence of dental caries in a group of American Indian children at high risk for early childhood caries. Methods This was an observational study in an American Indian community. Starting in 2002 all children received fluoride varnish applications at well child care visits at 9, 12, 15, 18, 24 and 30 months. The Head Start class of 2003 served as historical controls and students in 2004 and 2005 had increasing number of fluoride varnish treatments. All children entering Head Start from 2003 to 2005 had dental exams to determine the number of decayed, missing and filled surfaces (dmfs) present. The number of dmfs for each child was correlated with the number of fluoride varnish treatments received. Results Children with 4 or more treatments had 15.5 dmfs (95%CI 10.8–20.4) versus children with no fluoride varnish treatments who had 23.6 dmfs (95%CI 19.5–25.8) for a 35% decrease in overall caries. Children who received 1, 2 or 3 treatments showed no significant difference in dmfs when compared with children who had no fluoride varnish applications. Conclusions Fluoride varnish applied at well child care visits can reduce early childhood caries in American Indian children. Consideration should be given to making fluoride varnish more available to American Indian and Alaska Native children at well child visits. These findings may be applicable to other children who are at increased risk for early childhood caries.

     

急性氟中毒小鼠大脑皮层神经元DNARNA和NOS的活性观察

目的:探讨急性氟中毒对小鼠神经系统损害的机制。方法:选用昆明种小鼠24只,分为对照组、低氟组、中氟组、高氟组,每组6只,染氟组分别腹腔注射氟化钠(NaF)8.75、17.53、5 mg/kg,对照组同期注射等剂量生理盐水。分别采用黄递酶(NADPH-d)染色和吖啶橙荧光染色法,观察动物大脑皮层一氧化氮合酶(NOS)活性的变化和皮层DNA及RNA荧光染色强度。结果:与对照组相比,中、低氟组阳性神经元数量明显增多(P<0.05),而高氟组差异不明显(P>0.05);给药组皮层DNA和RNA吖啶橙染色后的荧光强度弱于对照组,且随给药浓度加大强度越弱。结论:急性氟中毒可增强小鼠皮层NOS阳性神经元的表达,对皮层神经元DNA和RNA亦有损伤作用。     

“抗氟灵”预防氟中毒的实验研究

本文通过亚急性动物试验观察了“抗氟灵”对大鼠氟性损伤的预防效果。结果显示“抗氟灵”能增加大鼠的尿量,提高尿氟浓度,促进体内氟硼酸根离子的形成并随尿排出,导致机体血清氟浓度,骨氟和牙氟含量降低,从而减轻了机体内的氟负荷,这表明“抗氟灵”对预防防氟损伤有一定的效果。     

安徽淮北芦岭镇地方性氟中毒氟源调查及分析

为了探讨燃煤污染是否是安徽淮北地区氟中毒的主要氟源 ,选择芦岭镇作为调查点 ,测定了该地区饮水、粮食、蔬菜、室内外空气等样品中氟含量。经计算 ,总摄氟量为4.77mg/人·日 ,其中饮水占 82 .18% ,食物占 17.4% ,由呼吸道摄入的氟量仅占 0 .42 %。由呼吸道摄入的氟量不到大气卫生标准允许限量的四分之一 ,即燃煤氟污染对氟中毒影响很小 ,饮水摄入的氟量是氟中毒的主要原因。提示安徽淮北地区不存在燃煤污染型地方性氟中毒。     

氟的生物学作用——氟对骨的作用

氟是机体必需的微量元素之一,与人体生命活动及牙齿、骨骼组织代谢密切相关。但氟的安全阈窄,低氟与高氟均可引起骨病,因此探究氟对骨的作用意义重大。针对氟对骨的作用进行阐述,主要分为氟对成骨细胞、破骨细胞、骨矿化以及牙齿的作用。以期为骨质疏松症、牙龋病和氟骨病的基础和临床研究提供文献依据。     

Can the mineral elements intakes recommended for the French population be provided by a balanced diet?

The minerals intakes provided by a diet with a balanced amount of proteins, lipids and carbohydrates are slightly superior to those supplied by the usual diet. However, the micronutrients whose intakes provided by the usual diet are insufficient for some population groups (women for instance) remain "at risk" even with a balanced diet (fluorine, zinc, iron and copper). This conclusion is not altered when taking account of drinks. This study shows that it is the intake energetic level which seems to be the first factor contributing to the recommended minerals intakes.     

Determining the optimal fluorine dose in the drinking water of the South Center hydrological region of Haiti

This study aims at determining the optimal dose of fluorine in the drinking water in the South Center region of Haiti. This region has an average daily temperature ranging from 17 to 33 C. Water samples were collected from November 15th to December 20th 2000 on the water resource of some of the counties of the hydrological South Center region of Haiti. The results show that the concentration of fluorine in this region varies between 0 and 0.83 mg/litre. However, the calculated optimal dose based on the temperature measured show that fluorine concentration of water should be between 0.7 and 1 mg/litre.     

氟对小鼠子代生长发育的影响

观察结果显示，染氟各组仔鼠机体组织氟含量增高，大脑皮质神经细胞超微结构异常。０．４５ｍｇ／ｋｇ剂量组仔鼠已表现为体格和早期神经行为发育迟缓；而０．４５ｍｇ／ｋｇ剂量组３０日龄仔鼠血清溶血素水平显著增高。表明氟可经母体对仔鼠各系统的发育产生不同影响。