鼻内镜下T3期鼻内翻性乳头状瘤切除术

目的探讨鼻内镜下治疗T3期鼻腔鼻窦内翻性乳头状瘤的疗效。方法总结12例T3期鼻腔鼻窦内翻性乳头状瘤经鼻内镜手术切除的治疗效果。结果 12例随访7～36个月,仅2例术后复发(16.6%),其中1例累及上颌窦、筛窦与蝶窦,1例累及上颌窦、额窦、筛窦及蝶窦。结论鼻内镜下行T3期鼻腔及鼻窦内翻性乳头状瘤切除术有良好疗效。     

鼻内镜手术治疗鼻腔鼻窦内翻性乳头状瘤疗效观察

目的探讨经鼻内镜手术治疗鼻腔鼻窦内翻性乳头状瘤的疗效。方法回顾性分析28例经鼻内镜手术治疗的鼻腔鼻窦内翻性乳头状瘤的病例资料及术后随访情况。结果随访10—36个月,28例中5例复发,再次经鼻内镜手术后未再复发。结论鼻内镜手术视野清晰、创伤小、效果满意,是治疗鼻腔鼻窦内翻性乳头状瘤优先选择的方法。准确的术前评估、手术技巧和术后定期随访是影响疗效的主要因素。     

内翻性乳头状瘤切除术28例临床分析

目的探讨经鼻内镜手术治疗鼻腔鼻窦内翻性乳头状瘤的疗效。方法回顾性分析28例经鼻内镜手术治疗的鼻腔鼻窦内翻性乳头状瘤的病例资料及术后随访情况。结果随访3～7年,28例中4例复发,再次经鼻内镜手术后未再复发。结论经鼻内镜手术切除鼻腔鼻窦内翻性乳头状瘤疗效满意。准确的术前评估、骨膜下层切除肿瘤和术后定期随访是减少复发,提高疗效的主要因素。     

鼻内镜治疗鼻腔鼻窦内翻性乳头状瘤31例临床分析

目的探讨鼻内镜下切除鼻腔鼻窦内翻性乳头状瘤的方法及疗效。方法对31例鼻腔鼻窦内翻性乳头状瘤鼻内镜下先切除鼻腔、筛窦、蝶窦、额窦口、上颌窦口肿瘤及其基部黏骨膜,侵及上颌窦者经柯陆径路内镜下于骨膜下分离切除肿瘤。结果术后随访2.5～7年,平均3.8年。治愈28例(90.32%),复发3例(9.68%)。结论鼻内镜对鼻腔鼻窦内翻性乳头状瘤疗效确切。切除肿瘤及其基部黏骨膜,对侵及上颌窦者联合柯陆径路内镜下治疗,可有效预防术后复发。     

鼻内镜手术治疗鼻腔及鼻窦内翻性乳头状瘤36例分析

目的 探讨鼻腔及鼻窦内翻性乳头状瘤的临床特征、鼻内镜手术方法 及临床疗效.方法 对2005年5月2010年7月36例鼻腔及鼻窦内翻性乳头状瘤的临床资料进行回顾性分析.结果 全部病例随访1～3年,无一例并发症,32例一次性治愈,复发4例,经再次手术后治愈.结论 鼻内镜手术清除病灶是治疗鼻腔及鼻窦内翻性乳头状瘤的最有效方法,手术中应尽量扩大鼻窦的自然开口,手术后定期冲洗窦腔及定期复查可防治疾病的复发.     

鼻内镜下鼻腔鼻窦内翻性乳头状瘤切除术50例临床分析

目的回顾性分析鼻内镜下切除鼻腔鼻窦内翻性乳头状瘤的方法及疗效。方法对50例鼻腔鼻窦内翻性乳头状瘤患者,内镜下切除鼻腔鼻窦肿物及肿物基底部黏骨膜,对侵及上颌窦,尤其是内下角者,辅助柯陆氏入路彻底切除肿瘤。结果术后随访2～8年,50例患者中治愈42例（84%）,局部复发5例（10%）、恶变3例。结论鼻内镜手术治疗鼻腔鼻窦内翻性乳头状瘤疗效确切,对侵及上颌窦者辅已柯陆氏径路下内镜治疗。     

导读

鼻腔鼻窦内翻性乳头状瘤专题——中国耳鼻咽喉头颈外科,2012,19(5)王广科,史凌改,马崧,等.鼻内镜下泪前隐窝入路手术治疗复发性上颌窦内翻性乳头状瘤疗效观察赵仁伍,汪永干,史前妹,等.鼻腔鼻窦内翻性乳头状瘤发病及复发与人乳头状瘤病毒感染相关性Meta分析     

鼻内镜手术治疗鼻腔及鼻窦内翻性乳头状瘤的疗效观察

目的：观察鼻内镜手术治疗鼻腔及鼻窦内翻性乳头状瘤的疗效。方法：病理和临床诊断为鼻腔及鼻窦内翻性乳头状瘤16例,术前做鼻内镜检查及鼻窦CT扫描,全身麻醉鼻内镜下行鼻腔及鼻窦内翻性乳头状瘤切除术。结果：术后随访1～2年,16例患者术后复发2例。结论：鼻内镜手术是治疗Krouse Ⅰ～Ⅱ级鼻腔及鼻窦内翻性乳头状瘤的一种较好的方法,此方法的优点为视野清楚、创伤少、出血量少、复发率低、避免了面部切口。     

鼻内镜下切除鼻腔鼻窦内翻性乳头状瘤51例临床观察

目的探讨鼻内镜下治疗鼻腔鼻窦内翻性乳头状瘤的效果。方法对51例鼻腔鼻窦内翻性乳头状瘤单纯在鼻内镜下或联合其他手术路径进行手术治疗,创面用电刀烧灼处理,术后用抗生素3～4d预防感染。结果 51例术后随访1～3年,临床治愈45例;6例复发,经再次鼻内镜下手术治愈。结论鼻内镜下治疗鼻腔鼻窦内翻性乳头状瘤创伤小,疗效好,治愈率高,可作为治疗鼻腔鼻窦内翻性乳头状瘤的首选方法。     

鼻内镜下鼻腔鼻窦内翻性乳头状瘤手术32例

鼻腔鼻窦内翻性乳头状瘤属于上皮源性肿瘤，是临床上最常见的鼻腔鼻窦良性肿瘤，治疗首选外科手术。传统的手术方式多采取鼻侧切开术，手术创伤大且面部留有瘢痕。近几年随着鼻内镜手术器械及技术的提高和完善，鼻内镜下手术治疗鼻腔鼻窦内翻性乳头状瘤已广泛推广。我院1996年10月～2006年10月鼻内镜下手术治疗鼻腔鼻窦内翻性乳头状瘤32例，疗效满意，报道如下。     

鼻腔及鼻窦内翻性乳头状瘤临床分期中CT的作用

目的探讨鼻腔及鼻窦内翻性乳头状瘤临床分期中CT的应用价值。方法回顾性分析33例鼻腔及鼻窦内翻性乳头状瘤的CT影像资料及手术资料。结果按照Krouse分期标准,将本组病例分为四期(四组)。在每组中将CT分期与手术所见分期比较,结果如下(相符/不相符):T1期1/0,T2期22/2,T3期3/3,T4期2/0,总共28/5。结论鼻腔及鼻窦内翻性乳头状瘤虽无特异CT表现,但CT影像与手术所见对比显示,它能较准确判断肿瘤的侵及范围,是鼻腔及鼻窦内翻性乳头状瘤分期中不可缺少的资料之一。     

经鼻内镜治疗鼻腔鼻窦内翻性乳头状瘤18例

探讨内镜下切除鼻腔鼻窦内翻性乳头状瘤的效果。方法：对18例鼻腔鼻窦内翻性乳头状瘤患者行鼻内镜手术。结果：随访1～4.5年,仅1例复发。结论：鼻内镜治疗鼻腔鼻窦内翻性乳头状瘤有多视角、清晰度高、损伤小、不毁容等优点。     

鼻内窥镜手术切除鼻腔鼻窦内翻性乳头状瘤

［摘要］目的：探讨内窥镜下切除鼻腔鼻窦内翻性乳头状瘤的效果。方法：对15例鼻腔鼻窦内翻性乳头状瘤患者施行鼻内窥镜手术。结果：随访2～4年，仅1例复发，余者均未见复发。结论：鼻内窥镜有多视角、清晰度高、损伤小、不毁容等优点，是治疗鼻腔鼻窦内翻性乳头状瘤的一种很好的方法。     

Squamous cell carcinoma arising in inverted papilloma

A retrospective review of all cases of inverted papilloma at the University of Michigan from 1975 to 1992 revealed 51 cases of inverted papilloma. Of these, 14 (27%) had an associated squamous cell carcinoma (SCC). Eight (16%) were metachronous and 6 (11%) were synchronous. At a mean follow-up of 53 months, the disease-free survival of patients with carcinoma limited to the nasal cavity and paranasal sinuses was 57% (4/7) compared to 14% (1/7) of those patients presenting with disease extending beyond the nasal cavity and paranasal sinuses. The data also support the lateral rhinotomy approach with medial maxillectomy and ethmoidectomy as a minimum procedure followed by postoperative radiation therapy. The mean interval between the diagnosis of inverted papilloma and development of SCC was 63 months (range, 6 months to 13 years). Therefore, long-term follow-up with clinical examination and computed tomography (CT) scan is indicated for all patients with inverted papilloma.     

鼻腔鼻窦内翻性乳头状瘤手术治疗的疗效分析

目的：观察鼻内镜下鼻腔鼻窦内翻性乳头状瘤手术治疗的临床疗效。方法回顾性分析在我院诊治的鼻腔鼻窦内翻性乳头状瘤患者56例,采用鼻内镜或鼻内镜联合Caldwell-Luc手术治疗,总结其临床疗效。结果56例患者术后效果良好,无严重并发症发生。术后随访2年,6例病变复发,2例术腔存在炎性肉芽组织,48例痊愈,治愈率85.7%。结论鼻内镜手术是治疗鼻腔鼻窦内翻性乳头状瘤的有效手段。应根据肿瘤侵犯的范围不同而采取不同的术式,术后宜定期复查,以便及时妥当处理局部病变。     

鼻内镜下联合低温等离子刀切除鼻腔鼻窦内翻性乳头状瘤37例

目的 回顾性分析鼻腔鼻窦内翻性乳头状瘤的临床特点,探讨鼻内镜下联合低温等离子刀切除鼻腔鼻窦内翻性乳头状瘤的可行性。 方法 在鼻内镜下使用低温等离子刀切除37例鼻腔鼻窦内翻性乳头状瘤,根据Krouse分级标准:T1期8例,T2期18例,T3期11例。术后鼻内镜下随访4~10年。 结果 37例均在鼻内镜下成功使用低温等离子刀切除肿瘤,3例术后复发,再次手术未复发。 结论 鼻内镜下联合低温等离子刀切除T1-T3期鼻腔鼻窦内翻性乳头状瘤安全、微创,术后复发率低。     

鼻腔鼻窦内翻性乳头状瘤切除三种术式的探讨

目的：比较鼻腔、鼻窦内翻性乳头状瘤切除三种手术方式的疗效。方法：35例中，9例行鼻侧切开术，5例行面中部掀翻术，21例行鼻内镜手术。结果：随访6～36个月，鼻侧切开术后复发2例，面中部掀翻术后复发1例，鼻内镜术后复发2例。结论：三种术式比较, 鼻内镜有视野清晰，手术范围准确，且不影响美观等优点。     

A study of surgical procedures for inverted papilloma in the nasal cavity and paranasal sinuses

Inverted papilloma, although benign, recurs frequently and may become malignant, making definitive initial resection extremely important. We evaluated surgical procedures for recurrence and sites, with special reference to management of the orbital plate of the ethmoid and lacrimal bones, in 24 patients (32 cases) with inverted papilloma of the nasal cavity and paranasal sinuses undergoing surgical resection from 2000. Nine of the 32 showed recurrence, all around the ethmoid orbital plate. Up to 2002, recurrence was noted in 7 of 17 cases (41%), so we changed surgical selection criteria. Since 2003, we have conducted partial and combined excision of the orbital plate of the ethmoid and lacrimal bones (extended operation of the extranasal ethmoid and frontal sinuses) in cases in which tumors adhered to the orbital plate, noting recurrences in only 2 of 15 cases (13%). A number of reports advocate endoscopic sinus surgery to minimize invasiveness for inverted papilloma, but partial and combined excision of the orbital plate is indispensable, in progressive inverted papilloma cases to reduce recurrent.     

Minimally invasive treatment of the nasal inverted papilloma

BACKGROUND: The purpose of this work is to evaluate our results in the treatment of the nasal inverted papillomas with an endoscopic approach using a retrospective case series. METHODS: Between 1993 and 2000 we treated 27 patients with nasal inverted papillomas. All patients underwent endoscopic nasal surgery under general anesthesia. None of the inverted papillomas extended outside of the paranasal sinuses. All tissue samples underwent polymerase chain reaction and hybridization in situ to detect genetic sequences of the human papilloma virus and Epstein Barr virus. RESULTS: The study population consisted of 16 men and 11 women with a median age of 52 years (range, 22-77 years). Ten patients (37%) had undergone a previous nasal surgery. The median follow-up was 5 years (range, 2-8 years). None of the patients presented with bilateral nasal involvement or a synchronous carcinoma. Seven patients underwent an additional surgical approach (two endoscopic approaches via a Caldwel-Luc approach, four sublabial approaches via a Caldwel-Luc approach, and one external ethmoidectomy). There were no surgical complications. Two patients (7%) had recurrent papilloma 4 and 6 years after surgery and again underwent endoscopic resection. The amplification both by polymerase chain reaction and hybridization in situ for human papilloma virus and Epstein Barr virus were negative in the specimens from all patients. CONCLUSIONS: According to the literature and our own experience, we believe that the initial surgical management of primary and recurrent inverted papillomas limited to the nasal cavity and paranasal sinuses should be endoscopic sinus surgery.