男性常吃芹菜可防脱发

中年男人特别怕掉头发。调整生活方式,是可以帮助避免或推迟这一烦恼的。想要防止脱发,平时应多吃芹菜、香菜和西兰花,因为这三种食物都有抗雄性激素的作用,可以帮助预防谢顶。谢顶在医学上称之为雄激素源性脱发。是成年男性中最常见的一种脱发现象,     

“聪明绝顶”缘何更钟情男人

拥有健康浓密的头发一直是我们不懈的追求,然而不少男性朋友还是难以避免地成了“聪明绝顶”一族。“聪明绝顶”是我们对谢顶的一种诙谐叫法,又名雄激素源性脱发、早秃、男性型脱发等,它是一种雄性激素依赖性的遗传性毛发脱落,属于常染色体显性遗传性疾病,伴有可变的外显率。     

男性脱发影响性能力吗

已经谢顶多年的刘先生总是性生活力不从心,最近,听说95%的男性脱发是雄激素源性脱发,是不是自己的雄激素分泌太旺盛了,所以才导致脱发,这种“异常”会不会也是自己性能力受影响的原因?刘先生带着困惑找到了河南省中医院男科门诊的孙自学教授。脱发是局部雄激素过局造成的医生给刘先生做了一些基本的检查。结果发现,其血清中的雄激素指标基本正常。     

让人烦恼的脱发

一头乌黑浓密的头发是人体健美的标志.遗憾的是现在不少中青年男子头顶及两鬓角光秃无发,或头顶仅剩稀疏细软的毛发,头皮油腻光亮.这就是常见的男性型脱发,又称雄激素源性脱发、早秃、脂溢性脱发,俗称"秃顶".     

发际线后移小心脱发来袭

男性型脱发,也称为脂溢性脱发或雄激素性脱发,占所有脱发类型的95%。目前国内男性型脱发患病率为20.16%,患者超过1.3亿,即每5位男性中就有一人受男性型脱发困扰。     

雄激素受体在雄性激素源性脱发患者的表达观察

目的：了解雄激素受体（AR）在雄性激素源性脱发（AGA）患者顶部表皮、毛囊、皮脂腺、汗腺中的表达情况。方法：选取26例雄性激素源性脱发患者顶部、枕部以及10例非脱发者的顶部头皮标本,用免疫组织化学检测表皮、毛囊、皮脂腺、汗腺中AR的表达。结果：脱发患者头顶部毛囊、皮脂腺、汗腺AR表达均明显强于枕部和非脱发者枕部,差异均有统计学意义（P〈0.05）;脱发患者枕部毛囊、皮脂腺、汗腺AR表达与非脱发者顶部AR表达比较差异均无统计学意义（P〉0.05）;所有标本表皮中AR均为阴性。结论：AR在AGA患者头顶部毛囊、皮脂腺、汗腺的高表达,可能是AGA重要原因之一。     

男性，向脱发说不

男性型脱发,也称为脂溢性脱发、雄激素性脱发,占所有脱发类型的95％。数据显示,我国约20％的男性被脱发所困扰,且患病人群呈年轻化趋势,脱发已成为男性面临的重要健康问题之一。本病影响美观,故患者治疗迫切。常常走入几个误区。     

关注女性“头顶大事”:防脱

最近,90后脱发的话题在网上被热议,折射了一个现状,就是为脱发问题困扰的人越来越多了!不仅是"英年早秃"的男性,还有发际线不断后退、头发日渐稀疏、需要各种掩饰头皮暴露尴尬的化妆品的女性。根据国内一项流行病学调查,雄激素性脱发,男性发生的比例是21.3%,而女性比例则是6%,而6%的比例也不低了。女性脱发是怎么回事?女性比男性更容易脱发吗?     

中年男性 远离脱发之忧

中国男性的脱发大军日趋“壮大”，据不完全统计，脱发发生率约占成人总人数的8％～9％，尤其以中老年男性脂溢性脱发最为常见。那么，是什么引起脱发的呢?男性该如何预防和治疗脱发?     

浓缩生长因子在雄激素源性脱发治疗中的研究进展

雄激素源性脱发(androgenetic alopecia,AGA)是影响男性和女性最常见的脱发形式,虽然目前已有数种可用的治疗选择,但人们还是在不断寻找一些更有效的治疗手段。浓缩生长因子(concentration growth factor,CGF)作为一种新型血小板制品已经成功应用在诸如骨科、口腔科、颌面外科、整形外科、皮肤科等众多领域,CGF可增强血管生成、细胞外基质重塑以及促进细胞的增殖和分化。CGF含有多种高浓度生长因子以及CD34阳性细胞群,其中的主要成分血小板衍生生长因子(platelet derived growth factor,PDGF)、转化生长因子(transforming growth factor,TGF)、血管内皮生长因子(vascular endothelial growth facto,VEGF)、表皮生长因子(epidermal growth factor,EGF)、胰岛素样生长因子(insulin-like growth factor,IGF)和肝细胞生长因子(hepatocyte growth factor,HGF)能有效刺激毛囊细胞生长、改善头皮微环境及头皮血供。尽管有可能成为治疗脱发的有效手段,但国内外关于CGF应用于脱发治疗的临床案例及疗效鲜有报道,也没有关于CGF对毛囊作用机制的评论文章。本文的目的在于介绍CGF及其在促进毛发生长中的有效作用机制,为患者的抗脱发治疗提供一种新的手段和方式。     

Scalp cooling for chemotherapy-induced alopecia

Alopecia is a very common side effect of cytostatic therapy and is considered one of the most emotionally distressing effects. To prevent alopecia scalp cooling is currently used in some indications in medical oncology in 59 hospitals in the Netherlands. The success of scalp cooling depends on various factors such as type of chemotherapy, dose, infusion time, number of treatment cycles and combinations of drugs. In general, scalp cooling is well tolerated. The reported side-effects are headache, coldness, dizziness and sometimes claustrophobia. An increase in the risk of scalp metastases has not been demonstrated. Proceeding from the South Netherlands Comprehensive Cancer Centre a national working group is put together in order to draw up a national guideline for chemotherapy-induced alopecia.     

应用斑秃治疗仪治疗斑秃患者的疗效观察

目的对145例斑秃患者发病情况分析及治疗效果评价。方法采用问卷调查方式对门诊就诊的145例斑秃患者进行调查,收集斑秃患者发病可能或伴发因素,并根据调查及临床检查结果对145例斑秃患者随机分组,并分别采用斑秃治疗仪(治疗组)和胱氨酸、天麻首乌片口服治疗(对照组)。结果治疗组治愈率为94.2%、有效率为98.1%,对照组治愈率为71.4%、有效率为81.0%。结论斑秃治疗仪治疗斑秃疗效优于对照组。     

斑秃患者107例生存质量及影响因素调查

[目的]对斑秃患者的生活质量进行评价并探讨其影响因素。[方法]应用皮肤病生活质量指数(der-matology life quality Index,DLQI)和非特异性生活质量量表(the short form-36 health survey,SF-36)对107例斑秃患者和102例对照组的生活质量进行量化评估,并比较两种方法评价差异。[结果]斑秃组DLQI评分高于对照组,差异有统计学意义(P<0.05);SF-36评分斑秃组低于对照组,在活力、情感职能、社会功能三个方面差异有统计学意义(P<0.05);逐步回归分析结果显示,病程、脱发面积及复发情况进入回归方程有统计学意义(P<0.05),且与DLQI结果正相关,与SF-36结果负相关。[结论]斑秃对患者的生活质量造成负面影响,应积极治疗;DLQI量表和SF-36量表适用于斑秃患者生活质量的评价;病程越长,脱发面积越大,复发的患者DLQI越高、SF-36越低,即生活质量越差。     

Clinical and biochemical manifestations of zinc deficiency in human subjects.

During the past two decades, essentiality of zinc for man has been established. Deficiency of zinc in man attributable to nutritional factors and several diseased states has been recognized. High phytate content of cereal proteins decreases availability of zinc; thus the prevalence of zinc deficiency is likely to be high in the population subsisting mainly on cereal proteins. Zinc deficiency has been noted to occur in patients with malabsorption syndrome, chronic renal disease, cirrhosis of the liver, sickle cell disease, AE (acrodermatitis enteropathica), and other chronically debilitating diseases. Growth retardation, male hypogonadism, skin changes, poor appetite, mental lethargy, and delayed wound healing are some of the manifestations of chronically zinc-deficient human subjects. In severely zinc-deficient patients, dermatological manifestations, diarrhea, alopecia, mental disturbances, and intercurrent infections predominate. If untreated, the condition becomes fatal. Zinc deficiency affects testicular functions adversely in man and animals. This effect of zinc is at the end-organ level. It appears that zinc is essential for spermatogenesis. Zinc is involved in many biochemical functions. Several zinc metalloenzymes have been recognized in the past decade. Zinc is required for each step of cell cycle in microorganisms and is essential for DNA synthesis. The effect of zinc on protein synthesis may be attributable to its vital role in nucleic acid metabolism. The activities of many zinc-dependent enzymes have been shown to be affected adversely in zinc-deficient tissues.(ABSTRACT TRUNCATED AT 250 WORDS)     

Clinical and biochemical manifestations of zinc deficiency in human subjects

During the past two decades, essentiality of zinc for man has been established. Deficiency of zinc in man attributable to nutritional factors and several diseased states has been recognized. High phytate content of cereal proteins decreases availability of zinc; thus the prevalence of zinc deficiency is likely to be high in the population subsisting mainly on cereal proteins. Zinc deficiency has been noted to occur in patients with malabsorption syndrome, chronic renal disease, cirrhosis of the liver, sickle cell disease, AE (acrodermatitis enteropathica), and other chronically debilitating diseases. Growth retardation, male hypogonadism, skin changes, poor appetite, mental lethargy, and delayed wound healing are some of the manifestations of chronically zinc-deficient human subjects. In severely zinc-deficient patients, dermatological manifestations, diarrhea, alopecia, mental disturbances, and intercurrent infections predominate. If untreated, the condition becomes fatal. Zinc deficiency affects testicular functions adversely in man and animals. This effect of zinc is at the end-organ level. It appears that zinc is essential for spermatogenesis. Zinc is involved in many biochemical functions. Several zinc metalloenzymes have been recognized in the past decade. Zinc is required for each step of cell cycle in microorganisms and is essential for DNA synthesis. The effect of zinc on protein synthesis may be attributable to its vital role in nucleic acid metabolism. The activities of many zinc-dependent enzymes have been shown to be affected adversely in zinc-deficient tissues.(ABSTRACT TRUNCATED AT 250 WORDS)     

Loss of cranial-nerve function caused by early syphilitic meningitis: the comeback of a pre-war syndrome

Two men aged 39 and 38 who had had unprotected insertive and receptive anal sexual contact with men are presented: one had paralysis of the right half of his face and the other man had erythematous macules on the palms of his hands and the soles of his feet as well as partial alopecia, earache and progressive loss of hearing in his left ear. The latter one was also HIV-seropositive and on antiretroviral medication. Syphilitic meningitis was diagnosed in both men. The 2 patients recovered after being treated with intravenous benzyl penicillin. Syphilitic meningitis is a complication seen during the early stages of a syphilis infection. Since the introduction of penicillin it has become a rare disease. Early diagnosis is of importance since syphilitic meningitis has irreversible sequelae.     

Alopecia universalis following two sequential traffic accidents: possible association with increased Th1 and Th17 cells and decreased Th2 cells

A 37-year-old Japanese man presented with alopecia after being involved in a traffic accident. An immunohistochemical study of the biopsy specimen demonstrated that CD8+ T cells infiltrated into hair follicles with satellite cell necrosis of keratinocytes. Four weeks after his initial visit, he again had another traffic accident. Despite the treatment with oral prednisolone and a topical steroid, the alopecia became universalis. Treatment with systemic and topical steroids was continued, and 12 weeks later, white vellus hairs grew over the whole scalp. Intracytoplasmic study revealed that there was a positive correlation between the severity of the alopecia and the increase of interferon-gamma producing Th1 cells or interleukin (IL)-17 producing Th17 cells, whereas the number of IL-4 expressing Th2 cells was inversely proportional to the extent of alopecia. The autoimmune hair loss might occur via the activation of T helper 1 (Th1) and Th17 cells.     

A failure to relax

Mr ST, a caucasian man aged 31 years, presented to hospital with weakness of his arms and legs. He felt unable to cope at home. Six weeks earlier, he sustained burns to his right hand, which occurred while trying to remove the radiator cap from his car. A review of hospital records revealed a history of hypertrophic cardiomyopathy, androgenic alopecia and abdominal pain, for which he had visited the cardiology, dermatology and gastroenterology departments respectively. Examination disclosed a slim male with frontal alopecia and wasted facial and proximal limb muscles. Reflexes were preserved, sensation intact. Notably, hand grip relaxation was delayed (myotonia). Haematological and biochemistry tests were unremarkable. Left ventricular hypertrophy and lateral T wave inversion were present on the electrocardiogram.     

Dermatologische Probleme bei Kindern mit Adipositas

While the impact of obesity on diabetes, cardiovascular disease and carcinoma development has been studied extensively, only little attention has been paid to its influence on the skin. Obesity alters the skin barrier, can induce skin manifestations, and worsens existing skin diseases like psoriasis. Cutaneous manifestations of obesity may be pseudoacanthosis nigricans, fibroma pendulans (skin tags, fibroepithelial polyps) and striae distensae. Obesity is also associated with hyperandrogenism in women and girls, promoting acne vulgaris, hirsutism, and androgenetic alopecia. In addition, there is a pathogenic association between obesity and psoriasis: the release of pro-inflammatory factors from fat tissue results in the worsening of psoriasis; an association between the severity of psoriasis and the body mass index has been shown. Obesity promotes skin infections like erysipelas and intertrigo.