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目的:总结汶川地震中理县卫牛防疫的经验,为地震活跃带地区的灾后卫生防疫工作提供参考.方法:针对汶川地震后重灾区理县存在的城市环境污染及次生危害问题,采取如下对策:①科学实施现场消毒和杀虫;②突击开展环境卫生整治;③经常进行环境设施维护;④及时排除防疫化学药品的危险隐患.结果:有效地改善了灾后居民安置环境的卫生质量,避免了重大疫情和公共卫生安全事件的发生.结论:有效整治环境卫生及排除次生危害隐患不仅可以缓解消毒、杀虫工作的压力,还可使居民生活环境更加美化、安全.在灾后城市卫生防疫工作中起到十分重要的作用. 相似文献
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目的:总结汶川地震中理县卫生防疫的经验,为地震活跃带地区的灾后卫生防疫工作提供参考。方法:针对汶川地震后重灾区理县存在的城市环境污染及次生危害问题,采取如下对策:①科学实施现场消毒和杀虫;②突击开展环境卫生整治;③经常进行环境设施维护;④及时排除防疫化学药品的危险隐患。结果:有效地改善了灾后居民安置环境的卫生质量,避免了重大疫情和公共卫生安全事件的发生。结论:有效整治环境卫生及排除次生危害隐患不仅可以缓解消毒、杀虫工作的压力,还可使居民生活环境更加美化、安全,在灾后城市卫生防疫工作中起到十分重要的作用。 相似文献
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<正>2008-05-12四川汶川地震发生后,随着遇难者的遗体陆续被挖掘、大量灾民转移和集中安置,饮水饮食安全、环境卫生,消毒杀虫,传染病预防等一系列卫生防疫问题接踵而 相似文献
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目的总结汶川地震后过渡期的疾病控制工作措施,保障灾区群众健康。方法根据地震灾区过渡期卫生防疫工作的实践经验,进行回顾性总结分析。结果总结出重点落实的6项防疫措施:①摸底调查,制定灾区防疫工作计划。②大力开展卫生宣教,让村民养成良好的卫生习惯。③搞好环境卫生,认真开展消杀灭等工作。④进行水质检验,确保饮水安全。⑤加强重点疾病的监测防控,防止传染病暴发流行。⑥加强食品卫生管理,防止发生食源性疾病。采取上述措施后,灾区无传染病暴发流行,无发生群体性食物中毒,实现了大灾之后无大疫的目标。结论采取各项预防措施对于预防地震灾后传染病的流行具有重大的意义。 相似文献
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2012年9月7日,云南省彝良县先后发生5.7级和5.6级地震,造成重大财产损失和人员伤亡;9月11日,县城又下了暴雨,灾区卫生防疫形势严峻。面对复杂多变的情况,国家、省、市、县疾病预防控制中心联合成立卫生防疫指挥部,组织专家制定地震灾区疾病防控工作方案,整合相关资源和力量,开展了较全面的现场卫生防疫工作,经过2个月的努力,灾后防疫取得阶段性成果,实现了大灾之后无大疫的目标,积累了防疫工作经验。 相似文献
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赴川抗震救灾卫生防疫工作的做法和体会 总被引:1,自引:1,他引:0
2008年5月12日汶川发生特大地震,根据军委、总部和军区指示,我部与驻宁第81医院、第454医院奉命抽组派出由疾病预防控制、卫生监督监测、传染病防治等人员组成的卫生防疫队[1],携带卫生防疫车辆和大量防疫专业药品器材紧急奔赴灾区开展卫生防疫工作。卫生防疫队在灾区历时近两个月,对在四川省什邡市和绵竹市等驻点救援部队实施伴随卫生防疫保障,直接保障5 600多人;先后派出防疫人员近千人次,行程3 300多公里,深入什邡市、绵竹市11个乡镇灾民点、帐篷区、板房居住点积极开展卫生防疫工作;派出10个防疫小组,采取乘坐直升机、公路机动等方式,行程1 200多公里分赴绵竹市清平乡和汉旺镇等重灾乡镇为数千名灾民临时安置点和部队救援官兵实施应急机动卫生防疫保障,出色地完成了任务,为实现灾区“大灾之后无大疫”做出了应有的贡献。1灾区卫生防疫工作特点[2]①环境卫生差,地震后灾区面临大面积废墟,人畜粪便垃圾尸体等急待处理,蚊蝇大量滋生,密度增高。②饮水饮食易受污染,供给困难。③灾民集中安置点人口密集,卫生设施不健全,卫生习惯较差。④灾民卫生防病知识急待普及,震后极易发生传染性疾病流行。⑤专业卫生防疫人员比较缺乏,基层防疫人员卫生... 相似文献
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“预防为主”是我军卫生防病工作的一条重要指导思想。我部地处闽南沿海 ,远离城市 ,单位分散 ,营区不封闭 ,与地方群众接触较多 ,居住生活环境条件较差 ,疫情反馈不及时 ,食品饮用水的防疫工作难以做到位 ,同时每年部队在营区外海训、驻训多 ,时间长 ,在生疏环境下卫生防疫工作的重要性尤显突出。现就如何加强旅团卫生队卫生防疫工作提出以下几点思考 :1 旅团卫生队防疫工作的现状1 .1 无专业防疫军医编制 ,基层卫生防疫工作的技术保障薄弱 就现行我军的编制体制而言 ,师医院设有防疫所及专业防疫人员编制 ,而集团军卫生处及旅团卫生队… 相似文献
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The concept that oestrogen replacement therapy is cardioprotective has been challenged recently by the negative results of randomized clinical trials in coronary heart disease. These data have come at a time of rapid advances in our understanding of the cellular mechanisms of oestrogen. In particular, the cloning of the classical oestrogen receptor (ERalpha), the identification of a novel ER isoform (ERbeta), the availability of specific ERalpha and ERbeta knockout mice models, and the elucidation of receptor functions and signalling pathways linked to non-genomic actions of oestrogen are helping to unravel this complex biology. In this article, these advances will be discussed with particular emphasis on the regulation of nitric oxide synthesis by oestrogen. Furthermore, the puzzling issues that have emerged and the potential for development of novel and specific therapeutic approaches will be highlighted. 相似文献
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The history of ketamine and phencyclidine from their development as potential clinical anaesthetics through drugs of abuse and animal models of schizophrenia to potential rapidly acting antidepressants is reviewed. The discovery in 1983 of the NMDA receptor antagonist property of ketamine and phencyclidine was a key step to understanding their pharmacology, including their psychotomimetic effects in man. This review describes the historical context and the course of that discovery and its expansion into other hallucinatory drugs. The relevance of these findings to modern hypotheses of schizophrenia and the implications for drug discovery are reviewed. The findings of the rapidly acting antidepressant effects of ketamine in man are discussed in relation to other glutamatergic mechanisms.Tables of Links
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Open in a separate windowThese Tables list key protein targets and ligands in this article which are hyperlinked to corresponding entries in http://www.guidetopharmacology.org, the common portal for data from the IUPHAR/BPS Guide to PHARMACOLOGY (Pawson et al., 2014) and are permanently archived in the Concise Guide to PHARMACOLOGY 2013/14a,b,c,dAlexander et al., 2013a,b,c,d,,,). 相似文献
TARGETS | |
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GPCRsa | Ligand-gated ion channelsb |
κ receptor | AMPA receptors |
μ receptor | GluN2A |
ACh receptors (muscarinic) | GluN2B |
Cannabinoid receptors | GluN2C |
D2 receptor | GluN2D |
Metabotrophic glutamate receptors | Kainate receptors |
Enzymesd | NMDA receptors |
Cholinesterases | Nicotinic ACh receptors |
GAD-67 | |
GSK-3 | Ion channelc |
mTOR | HCN1 |
PKB (Akt) |
LIGANDS | ||
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5-HT | Dopamine | Morphine |
ACh | Ethylketocyclazocine | Naloxone |
AMPA | HA-966 | NMDA |
Amphetamine | Ifenprodil | Noradrenaline |
Bicuculline | Kainate | Pentazocine |
Chlorpromazine | Ketamine (CI-581) | Phencyclidine |
Cyclazocine | Levorphanol | Pregnenolone |
D-AP5 | LSD | Quisqualate |
Dextromethorphan | Memantine | U50488H |
Dizocilpine (MK-801) |
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医院以及医院药学的定位和服务方式转变 总被引:3,自引:0,他引:3
本文以新一轮医药卫生体制改革的内容为切入点,分析我国现有医院与医院药学的现状,并与国外医疗体系做对比;提出了公立医院的定位问题及如何发挥医院药学在医院中的作用,转变服务方式,加强药师队伍建设等问题。 相似文献
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Hydrogen sulfide is rapidly gaining ground as a physiological mediator of inflammation, but there is no clear consensus as to its precise role in inflammatory signaling. This article discusses the disparate anti-inflammatory ('the good') and proinflammatory ('the bad') effects of endogenous and pharmacological H(2)S in disparate animal model and cell culture systems. We also discuss 'the ugly', such as problems of using wholly specific inhibitors of enzymatic H(2)S synthesis, and the use of pharmacological donor compounds, which release H(2)S too quickly to be physiologically representative of endogenous H(2)S synthesis. Furthermore, recently developed slow-release H(2)S donors, which offer a more physiological approach to understanding the complex role of H(2)S in acute and chronic inflammation ('the promising') are discussed. 相似文献
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Klopack TG 《Drug discovery today》2000,5(4):157-160
Pharmaceutical research organizations can benefit from outsourcing discovery activities that are not core competencies of the organization. The core competencies for a discovery operation are the expertise and systems that give the organization an advantage over its competition. Successful outsourcing ventures result in cost reduction, increased operation efficiency and optimization of resource allocation. While there are pitfalls to outsourcing, including poor partner selection and inadequate implementation, outsourcing can be a powerful tool for enhancing drug discovery operations. 相似文献
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