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精神分裂症患者头发铜,铁,锰,锌,镁元素的含量

采用原子吸收光谱法测定了84例精神分裂症病人及其健康配对者头发 Cu、Fe、Mn、Zn、Mg 元素的含量,发现女性患者头发 Mn 和 Mg 含量以及 Cu/Zn 比值明显升高,而男性患者头发五种元素和女性患者头发 Cu、Fe、Zn 含量与健康人比较却无明显改变。     

精神分裂症病人头发锌,铜,铁,钙,镁含量的测定

探讨锌，铜，铁钙，镁微量元素含量与精神分裂症的关系。方法采用原子吸收分光光度计对７５例精神分裂症病人和６０名健康对照者的头发锌，铜，铁，钙，镁的含量进行测定。结果．１．精神分裂症病人头发锌，镁含量较正常对照者代，而铜，铁，钙则增高；Ⅰ，Ⅱ型间比较，上述元素无差异；２．精神分裂症病人男性头发锌，镁含量高于女性；正常对照者头发钙，镁含量男性高于女性；３．抗精神病药治疗４０天后，病人头发锌含量较治疗前增     

紫绀,红细胞增多,杵状指,突然头痛,命名性失语

患者,男,23岁。突然剧烈头痛,说不出物品的名字1天,于1989年10月20日入院。 缘于1978年开始有轻度头晕,其母发现他有轻度发绀,未介意。1980年初出现劳累后心慌、气短,在当地医院疑为心脏病,后经胸部透视又疑为肺结核,抗痨治疗数月无效。同年5月出现鼻衄,每次出血量不多。3个月后首次住院。未去过高原地区,家族史无特殊。体检:面部皮肤、口唇、甲床均明显发绀,双腿皮肤有毛细血管     

精神分裂症患者头发铜,锌,钙,镁,铁含量的测定

采用原子吸收光谱法测定精神分裂患者头发Cu、Zn、Ca、Mg、Fe的含量,并与正常人做对照。结果精神分裂症组女性发Cu显著高于男性(P<0.05),而发Ca显著低于男性(P<0.05)。精神分裂症患者发 Cu、Zn、Ca、Mg、Fe五种微量元素的含量均显著低于正常人。提示精神分裂症患者存在体内微量元素含量的改变。     

头痛,发热,交叉性瘫痪

病历摘要 患者女性,25岁。头痛,发烧伴呕吐半月于1989年1月6日入院.发病前21天自然分娩。检查:神志清,心肺及腹部未见异常。神经系统除脑膜刺激征(十)外无阳性发现。腰穿7次,压力由2.94～4.90kPa(300～500mmH_2O),外观微浑,白     

Ⅰ,Ⅱ型精神分裂症病人血清及红细胞锌,铜,铁,钙,鲜含量测定

本文对７５例精神分裂症及４０例健康对照者血清及红细胞锌，铜，铁，钙，镁含量进行了检测。结果显示：１．在血清测定中Ⅰ，Ⅱ型锌，镁较对照组低，而铜，铁，钙，则高，ⅠⅡ型间上述元素比较无差异。２．在红细胞测定中Ⅰ型铜含量较对照组高，镁则减少，Ⅱ型铜，铁钙较对照组高，镁则减少，Ⅰ－Ⅱ型间比较，Ⅰ型锌，铁较Ⅱ型降低，镁则增高。３．相关检发现Ⅰ型中血清及红细胞锌，铜含量呈正相关。     

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6th Dysferlin Conference, 3–6 April 2013, Arlington,Virginia, USA

The 2013 Dysferlin Conference, sponsored and organized by the Jain Foundation, was held from April 3–6, 2013 in Arlington, VA. Participants included 34 researcher speakers, 5 dysferlinopathy patients and all 8 members of the Jain Foundation team. Dysferlinopathy is a rare disease that typically robs patients of mobility during their second or third decade of life. The goals of these Dysferlin Conferences are to bring experts in the field together so that they will collaborate with one another, to quicken the pace of understanding the biology of the disease and to build effective platforms to ameliorate disease. This is important because the function of dysferlin and how to compensate for its absence is still not well understood, in spite of the fact that the dysferlin gene was identified more than a decade ago. The objective of this conference, therefore, was to share and discuss the newest unpublished research defining the role of dysferlin in skeletal muscle, why its absence causes muscular dystrophy and possible therapies for dysferlin-deficient muscular dystrophy patients.     

分子~*细胞生物学常用词汇(T,U,V,W,X,Z部)

TATAbox/TATA框　多种真核细胞蛋白编码基因的启动子中的保守序列 ,转录起始复合物装配的所在。 telomere/端粒　真核生物染色体的末端区域 ,包含经特殊过程复制而成的特征性端粒 (TEL)序列 ,其作用是对抗染色体在每一轮复制中变短的倾向。 temperature-sensitive(ts)mutant/温度敏感性突变体　具有编码异常(altered)蛋白基因的细胞或生物体 ,这种蛋白只在某一温度 (允许温度 )下才发挥正常功能 ,而在其他温度 (非允许温度 )下则没有功能。 template/模板　一个决定另一个分子结构的分子“模型” ,最常见的是 ,DNA的一条链引导DNA复…     

Report on the Myomatrix Conference April 22–24, 2012, University of Nevada,Reno, Nevada,USA

The Myomatrix 2012 conference held April 22–24th, 2012 at the University of Nevada, Reno convened 73 international participants to discuss the dynamic relationship between muscle and its matrix in muscular dystrophy with a specific focus on congenital muscular dystrophy. Seven sessions over 2½ days defined three central themes: (1) the role of extracellular matrix proteins and compartments in development and specifically in congenital muscular dystrophy (CMD) (2) the role of extracellular matrix signaling and adhesion to membrane receptors and (3) the balance and interplay between inflammation and fibrosis as drivers of altered matrix stiffness, impaired regeneration and progressive dystrophy. This report highlights major conference findings and the translational roadmap as defined by conference attendees.