不同活化剂对稳定态二氧化氯消毒效果的比较

在稳定条件下,二氧化氯杀菌作用弱,一旦加酸活化则杀菌效果迅速出现。用不同活化剂活化稳定态二氧化氯的消毒效果不同。本文对盐酸与柠檬酸活化稳定态二氧化氯的消毒效果进行了比较。１材料与方法１．１试剂稳定态二氧化氯,４％盐酸溶液,柠檬酸,５ｇ／Ｌ硫代硫酸钠磷...     

不同活化剂对稳定态二氧化氯消毒效果的比较研究

目的比较盐酸和柠檬酸作为活化剂对稳定态二氧化氯的消毒效果。方法以盐酸和柠 檬酸作活化剂,评价稳定态二氧化氯的消毒效果。结果当消毒剂为４．５ｍｇ·Ｌ－１时,消毒２ｍｉｎ, 对大肠杆菌的杀灭率分别为９９． ９９％及７８． ００％,对金黄色葡萄球菌的杀灭率分别为９９． ９９％及 ９６． ２５％。当消毒剂为９０ｍｇ·Ｌ－１时,１５ ｍｉｎ对细菌芽孢的杀灭率分别为９９．９９％及９７．００％。加 １０％小牛血清的菌悬液要达消毒效果,用盐酸活化只需１８０ ｍｇ·Ｌ－１作用５ｍｉｎ,而柠檬酸则需 ２７０ ｍｇ·Ｌ－１作用１５ ｍｉｎ。以盐酸为活化剂,二氧化氯２００ ｍｇ·Ｌ－１,５ ｍｉｎ即可灭活ＨＢｓＡｇ;而柠檬酸则需４００ ｍｇ·Ｌ－１。结论作为稳定态二氧化氯的活化剂,盐酸明显地优于柠檬酸。     

不同活化剂对稳定态二氧化氯消毒效果的比较研究

目的比较盐酸和柠檬酸作为活化剂对稳定态二氧化氯的消毒效果.方法以盐酸和柠檬酸作活化剂,评价稳定态二氧化氯的消毒效果.结果当消毒剂为4.5 mg·L-1时,消毒2 min,对大肠杆菌的杀灭率分别为99.99%及78.00%,对金黄色葡萄球菌的杀灭率分别为99.99%及96.25%.当消毒剂为90 mg·L-1时,15 min对细菌芽孢的杀灭率分别为99.99%及97.00%.加10%小牛血清的菌悬液要达消毒效果,用盐酸活化只需180 mg·L-1作用5 min,而柠檬酸则需270 mg·L-1作用15 min.以盐酸为活化剂,二氧化氯200 mg·L-1,5 min即可灭活HBsAg;而柠檬酸则需400 mg·L-1.结论作为稳定态二氧化氯的活化剂,盐酸明显地优于柠檬酸.     

稳定态二氧化氯与碱性戊二醛消毒效果的比较

对稳定态二氧化氯与碱性戊二醛的消毒效果进行比较。结果表明：4．5mg·L－1活化二氧化氛2min可杀灭细菌繁殖体99．99％,而碱性成二醛需1200mg·L－110min;全部杀灭细胞芽孢,活性二氧化氨为180mg·L－120min,而碱性成二醛需2400mg·L-1120min;灭活HBsAg,活性二氧化氯为200mg·L-15min,而碱性戊二醛需12000mg·L－110min。     

对建立我国医院信息主管制度的思考

随着信息化在医药卫生领域应用的深入．迫切需要在医院建立信息主管制度（CIO制度）。文章简单介绍了CIO制度在国内外的发展现状、建立CIO制度的必要性以及目前建立CIO制度面临的一些主要难题，对如何在我国建立医院信息主管制度进行了初步的探讨。     

抗菌肽在食品防腐剂中的研究应用

抗菌肽是生物防御系统产生的一类对抗外源性病原体的肽类物质,对细菌、部分真菌、病毒、原虫、肿瘤细胞都具有杀伤作用,它的杀菌和安全无毒害作用的优势使得它具有做天然食品防腐剂的潜在应用价值。本文分析综述了不同抗菌肽在食品防腐中的应用。     

CIO of the Year. Thriving on the challenge of change

To manage the change that confronts Harris Methodist Health System, Larry Blevins uses his technical knowledge, management and interpersonal skills, and business savvy. In 14 years with the Arlington, Texas-based health care system, Blevins has unified its information systems approach and given in the automation infrastructure to thrive. "If you're not changing, then you're either dead or stagnant," Blevins says. "While that is the challenge, that's part of the fun. Change should be fun."     

线粒体融合蛋白2对小鼠受精卵发育影响的研究

目的:观察线粒体融合蛋白2(Mitofusin2,Mfn2)对昆明小鼠受精卵发育的影响,探讨其在早期胚胎发育中的重要作用。方法:采用荧光定量PCR对昆明小鼠Mfn2基因反义序列进行沉默有效性的筛选,将所筛选的序列转染入小鼠2细胞受精卵中,观察并统计囊胚形成速率及质量。结果:成功筛选得到有效Mfn2基因反义序列,Mfn2基因沉默后囊胚形成速度减慢,且正常囊胚形成率明显减低。结论:Mfn2基因沉默组中的囊胚形成速率和数量明显降低,提示Mfn2参与小鼠受精卵的发育,推测Mfn2的正常表达对小鼠植入前胚胎发育具有重要作用。     

稳定型含氯消毒液研制及杀菌效果观察

目的:在含氯消毒剂加入不同成分比例的稳定剂和表面活性剂,以同时提高其杀菌效果与稳定性。方法:经过初筛,在次氯酸钠溶液中加入9种不同比例的稳定剂(XS-1)和多聚磷酸钠,检测其稳定性及对枯草杆菌黑色变种芽孢的杀灭能力。结果:有效氯含量与稳定剂(XS-1)的含量成正比,多聚磷酸钠对稳定性影响不明显;消毒剂有效氯含量均为500 mg/L时,分别作用30 m in,1 h的灭菌效果与多聚磷酸钠的含量成正比,与稳定剂(XS-1)的含量成反比。结论:经研制所得的稳定型含氯消毒液有效氯含量为4.90%~4.94%,置54℃14天有效氯下降率为15.1%~18.2%,表明在室温情况下有效期可接近一年,并且有良好的杀灭枯草杆菌黑色变种芽胞的效果。     

苹果皮提取物对2型糖尿病的作用研究

目的探讨苹果皮提取物(apple peel extract,APE)对胰岛素耐性有关的肥胖病以及由高脂肪食物引起的2型糖尿病的作用。方法以8周龄期的C57BL/6小鼠为实验模型,分为饲喂高脂食物组(HF组)、饲喂低脂食物组(LF组)、HF+APE组、LF+APE组,对比饲小鼠的体重、血糖、胰岛素和甘油三酯水平。结果 APE明显改善了HF小鼠对糖的耐受性和胰岛素的敏感性,口服APE的HF小鼠炎症早期细胞因子水平和脂肪组织中氧化水平显著降低。结论 APE能部分提高C57BL/6小鼠抗感染和抗氧化的能力,也能有助于2型糖尿病的治疗。     

Effect of storage of shelled Moringa oleifera seeds from reaping time on turbidity removal

Moringa oleifera is an indigenous plant to Malaysia whose seeds are used for water purification. Many studies on Moringa oleifera have shown that it is highly effective as a natural coagulant for turbidity removal. In this study, two different methods for extraction of Moringa's active ingredient were investigated. Results of sodium chloride (NaCl) and distilled water extraction of Moringa oleifera seeds showed that salt solution extraction was more efficient than distilled water in extracting Moringa's active coagulant ingredient. The optimum dosage of shelled Moringa oleifera seeds extracted by the NaCl solution was comparable with that of the conventional chemical coagulant alum. Moreover, the turbidity removal efficiency was investigated for shelled Moringa oleifera seeds before drying in the oven under different storage conditions (i.e. open and closed containers at room temperature, 27 °C) and durations (fresh, and storage for 2, 4, 6 and 8 weeks from the time the seeds were picked from the trees). Our results indicate that there are no significant differences in coagulation efficiencies and, accordingly, turbidity removals between the examined storage conditions and periods.     

The effect of dietary supplements on the nPCR in stable hemodialysis patients.

OBJECTIVE: To investigate whether (1) dietary supplements raise the normalized protein catabolic rate (nPCR) and/or further improve the nutritional status of stable hemodialysis patients who have both a low nPCR and a low dietary protein intake, <1.2 g/kg body weight/day; and if (2) protein intake measured by nPCR reflects protein intake measured by estimated food diaries in stable patients. DESIGN: Prospective experimental study with a single intervention group. SETTING: Hospital outpatient hemodialysis unit. SUBJECTS: Seventeen stable chronic hemodialysis patients (10 men, 7 women) were studied over 8 months. INTERVENTION: Subjects with both a low nPCR and dietary protein intake <1.2 g/kg body weight/day received dietary supplements for the first 2 months. Measurements to assess protein intake and nutritional status were taken at baseline and repeated at the end of 2 months, and at 6 months postintervention. MAIN OUTCOME MEASURE: nPCR, dietary protein intake using 7-day estimated food diaries, serum urea, serum albumin, serum creatinine, serum bicarbonate, dialysis adequacy (Kt/V), and body mass index (BMI). RESULTS: Dietary supplements significantly increased both the nPCR and the total protein intake at 2 months (1.21 +/- 0.26, 1.10 +/- 0.12, respectively) compared with baseline (0.95 +/- 0.18, 0.75 +/- 0.19, respectively) and 8 months (0.99 +/- 0.12, 0.78 +/- 0.21, respectively), P <.0001, respectively. There was no change in the nutritional status of the subjects. There was a significant difference between the nPCR and the dietary protein intake at baseline, P <.004; at 2 months, P <.047; and at 8 months, P <.001. CONCLUSION: Dietary supplements can significantly increase the nPCR and dietary protein intake in stable hemodialysis patients with a low nPCR and dietary protein intake. Because a low nPCR is associated with a high morbidity and mortality rate, it may be prudent to supplement such patients. The use of the nPCR to quantify dietary protein intake in stable hemodialysis patients should be used with caution.