| 北京海淀社区2型糖尿病患者用药现状调查及情况分析 |
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| 引用本文： | 崔芳囡,汤欣,牛红丽,姜岳,赵付英.北京海淀社区2型糖尿病患者用药现状调查及情况分析[J].中华全科医学,2022,20(9):1531-1534. |
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| 作者姓名： | 崔芳囡 汤欣 牛红丽 姜岳 赵付英 |
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| 作者单位： | 1.中国人民大学医院内科，北京 100872 |
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| 基金项目： | 首都卫生发展科研专项项目首发2018-3-7035 |
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| 摘 要： | 目的 了解北京海淀区社区建档2型糖尿病(T2DM)患者的用药现状，分析合并用药的原因及多重用药的问题，为临床合理用药提供依据。 方法 选取在中国人民大学社区卫生服务中心建立T2DM慢病档案，在2020年1月1日—12月31日期间规律就诊6个月及以上的患者。记录患者的基本信息、确诊时间、合并疾病和用药。 结果 研究共纳入T2DM患者467例，男女性别比为1∶ 1.02，年龄为37~98岁，病程为0.5~37.5年，用药5(4, 7)种。419例患者采用药物控制血糖，41.77%(175/419)的患者使用单药降糖。72.55%(304/419)应用含二甲双胍的降糖方案，50.84%(213/419)应用含α-糖苷酶抑制剂的降糖方案，23.40%(98/419)应用磺脲类，22.91%(96/419)使用含胰岛素降糖方案，5.73%(24/419)应用二肽基肽酶Ⅳ(DPP-4)抑制剂类降糖方案；70.45%(329/467)的患者联合调脂治疗，54.39%(254/467)的患者联合抗血小板聚集药物治疗，74.73%(349/467)的患者服用降压药。60.17%(281/467)的患者同时服用5种及以上的药物。随着病程的延长，患者合并用药的数量逐渐增加，患者多重用药的种类与病程呈正相关(r=0.177，P＜0.001)。 结论 北京海淀区社区建档的T2DM患者多重用药普遍，存在医疗安全隐患，医生应对患者加强管理，优化用药方案，保证医疗安全。
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| 关 键 词： | 2型糖尿病 调查 合并疾病 多重用药 |
| 收稿时间： | 2021-05-09 |
Investigation and analysis of drug use status of patients with type 2 diabetes in the Haidian community of Beijing |
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| Affiliation: | Internal Department, Beijing Renmin University Hospital, Beijing 100872, China |
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| Abstract: | Objective To investigate the drug use status of type 2 diabetes (T2DM) patients in the Haidian District of Beijing, to analyse the reasons for the concomitant medication and the problem of polypharmacy, and to provide the basis for clinical rational drug use. Methods Patients who established the chronic disease file of T2DM in the community health service of the People ' s University of China and had been regularly visited for 6 months or longer between January 1, 2020 and December 31, 2020 were selected. The basic information of patients, the time of diagnosis of T2DM, comorbid diseases, and current medication were recorded. Results A total of 467 patients with T2DM were included in this study. The ratio of male to female was 1∶ 1.02, the age was 37 - 98 years, the course of disease was 0.5-37.5 years, and the medication was 5 (4, 7) species. Amongst them, 419 patients used drug intervention to control blood glucose, and 41.77% (175/419) patients used single-drug hypoglycaemic therapy. A total of 72.55% (304/419) patients used metformin containing hypoglycaemic regimen, 50.84% (213/419) patients were treated with α-glucosidase inhibitor, 23.40% (98/419) patients used sulphonylurea, 22.91% (96/419) patients used insulin, and 5.73% (24/419) patients used dipeptidyl peptidase 4 inhibitor. A total of 70.45% (329/467) patients used lipid-lowering therapy, 54.39% (254/467) patients continued to use antiplatelet aggregation drugs therapy, and 74.73% (349/467) patients used a combination of antihypertensive drugs. A total of 281 patients (60.17%) took five or more drugs at the same time for a long time. With prolonged disease course, the number of combined medications increased gradually, and the number of concomitant medications was positively correlated with the duration of diabetes (r=0.177, P < 0.001). Conclusion In the Haidian community of Beijing, T2DM patients with multiple-drug use are common, and hidden medical risks exist. Doctors should strengthen the management of patients, optimise the medication plan, and ensure medical safety. |
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