| 中青年急性缺血性脑血管病大脑中动脉斑块特点分析 |
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| 引用本文： | 宋建龙,王梓,魏建林,刘畅,胡伟,夏成雨,朱余友.中青年急性缺血性脑血管病大脑中动脉斑块特点分析[J].中华全科医学,2021,19(11):1811-1814. |
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| 作者姓名： | 宋建龙 王梓 魏建林 刘畅 胡伟 夏成雨 朱余友 |
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| 作者单位： | 1.中国科学技术大学附属第一医院神经内科，安徽 合肥 230001 |
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| 基金项目： | 安徽省2018年度重点研究与开发计划项目1804h08020250安徽省2019年度重点研究与开发计划项目201904a07020086 |
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| 摘 要： | 目的 应用高分辨率磁共振血管壁成像研究中青年急性缺血性脑血管病大脑中动脉斑块的特点。 方法 收集2018年6月—2020年2月于中国科学技术大学附属第一医院神经内科住院的74例中青年急性缺血性卒中或短暂性脑缺血发作患者资料，责任血管均为大脑中动脉，利用高分辨率磁共振评估斑块分布位置、性质，比较症状侧和无症状侧大脑中动脉和不同性质斑块的位置分布特点。 结果 共扫描74例患者，其中颅内动脉粥样斑块62例，共124根大脑中动脉，其中症状侧血管48根(38.7%)，非症状侧血管76根(61.3%)。血管内存在斑块96根，稳定斑块39根(40.6%)，不稳定斑块57根(59.4%)；上侧16根(16.7%)，下侧38根(39.6%)，背侧10根(10.4%)，腹侧32根(33.3%)。症状侧和非症状侧大脑中动脉不稳定斑块分别有41根和16根(P < 0.01)；稳定斑块和不稳定脉斑块位置(腹侧10根vs. 22根，背侧2根vs. 8根，上侧5根vs. 11根，下侧22根vs. 16根，P < 0.05)；症状侧和非症状大脑中动脉斑块位置(腹侧16根vs. 16根，背侧6根vs. 4根，上侧9根vs. 7根，下侧14根vs. 24根，P>0.05)。 结论 中青年急性缺血性脑血管病患者大脑中动脉斑块主要分布于血管的下侧和腹侧，症状侧斑块性质多为不稳定斑块，多分布在大脑中动脉的腹侧、背侧和上侧。
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| 关 键 词： | 缺血性脑血管病 中青年 动脉粥样硬化斑块 大脑中动脉 血管壁成像 |
| 收稿时间： | 2020-07-05 |
Analysis on the characteristics of middle cerebral arterial plaque in young and middle-aged patients with acute ischemic cerebrovascular disease |
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| Affiliation: | Department of Neurology, the First Affiliated Hospital of USTC, Hefei, Anhui 230001, China |
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| Abstract: | Objective To study the characteristics of middle cerebral artery plaques in young and middle-aged adults with acute ischemic cerebrovascular disease using high-resolution magnetic resonance vessel wall imaging. Methods We collected 74 young and middle-aged patients with acute ischemic stroke or transient ischemic attack hospitalised from June 2018 to February 2020 using high-resolution magnetic resonance imaging to evaluate the location and nature of plaques and to compare the location distribution characteristics of symptomatic and asymptomatic middle cerebral arteries and plaques of different properties. Results There were 74 patients, including 62 cases of intracranial atherosclerotic plaque. A total of 124 middle cerebral arteries were scanned by magnetic resonance imaging in 62 patients, of which 48 were symptomatic side vessel roots (38.7%) and 76 were non-symptomatic lateral vessels (61.3%). There were 96 plaques, 39 stable plaques (40.6%), 57 unstable plaques (59.4%), 16 superior plaques (16.7%), 38 inferior plaques (39.6%), 10 dorsal plaques (10.4%) and 32 ventral plaques (33.3%). There were 41 and 16 symptomatic and non-symptomatic central cerebral artery unstable plaques (P < 0.01); stable plaques and unstable plaque locations (ventral 10 vs. 22, dorsal 2 vs. 8, superior 5 vs. 11, inferior side 22 vs. 16, all P < 0.05); symptomatic side and non-symptomatic middle cerebral artery plaque location (ventral 16 vs. 16, dorsal 6 vs. 4, superior 9 vs. 7, inferior 14 vs. 24, all P < 0.05). Conclusion The middle cerebral artery plaques in young and middle-aged patients with acute ischemic cerebrovascular disease are mainly distributed in the lower and ventral side of the blood vessels, and the properties of symptomatic plaques are mostly unstable plaques, which tend to be distributed in the ventral, dorsal and upper side of the middle cerebral artery. |
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