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脑功能治疗仪联合心理干预治疗老年人药物过度使用性头痛的临床研究
引用本文:张冬梅,叶建新,秦茵,陈建鸿,余云华,崔晓萍.脑功能治疗仪联合心理干预治疗老年人药物过度使用性头痛的临床研究[J].中华全科医学,2019,17(3):439-442.
作者姓名:张冬梅  叶建新  秦茵  陈建鸿  余云华  崔晓萍
作者单位:1. 福建医科大学福总临床医学院(福州总医院)干部二科, 福建 福州 350025;
基金项目:全军保健专项课题(14BJZ30)
摘    要:目的 研究和探讨脑功能治疗仪联合心理干预对老年人药物过度使用性头痛(MOH)的临床疗效。 方法 选择2014年7月-2015年7月在福建医科大学福总临床医学院干部科、神经内科门诊序贯就诊的50~80岁确诊为MOH的患者共120例,按随机数表法分为观察组与对照组,每组各60例。对照组采用撤药及尼莫地平(30 mg,3次/d)预防性治疗;观察组在对照组的基础上采用YS7004脑功能治疗仪治疗及心理干预综合治疗,治疗4周后,对比2组患者治疗前后的VAS评分、头痛发作频率、血清碱性成纤维细胞生长因子(bFGF)浓度以评价患者头痛程度,对比焦虑自评量表(SAS)和抑郁自评量表(SDS)以评价患者心理状态,对比健康调查量表(SF-36)评价患者生活质量。 结果 ①治疗后2组患者VAS评分、头痛发作频率、血清碱性成纤维细胞生长因子(bFGF)浓度均较治疗前降低,且观察组降低幅度优于对照组,差异有统计学意义(P<0.01);②治疗后对照组患者SAS评分与SDS评分与治疗前差异无统计学意义(P>0.05),观察组治疗后SAS评分与SDS评分显著低于治疗前(P<0.01);③治疗后2组患者SF-36评分均较治疗前提高,且观察组提高更为显著,差异具有统计学意义(P<0.01)。 结论 在常规治疗的基础上联合脑功能治疗仪及心理干预治疗方法,对老年人药物过度使用性头痛具有更加显著的疗效,可以缓解头痛,改善焦虑、抑郁的心理,提高患者的生活质量。 

关 键 词:脑功能治疗仪    心理干预治疗    药物过度使用性头痛
收稿时间:2018-01-07

Clinical study of brain function therapy instrument combined with psychological intervention in the treatment of elderly patients with medication overuse headache
Affiliation:The Second Department of Cadre's Ward, Fuzhou General Clinical Teaching Hospital of Fujian Medical University (General Hospital of Fuzhou), Fuzhou, Fujian 350025, China
Abstract:Objective To study and explore the clinical efficacy of brain function therapy combined with psychological intervention in elderly patients with medication overuse headache (MOH). Methods From July 2014 to July 2015, 120 patients were diagnosed as MOH patients in the department of cadre's ward and department of neurology. The patients were divided into observation group and control group according to the random number table method, with 60 cases in each group. The control group was treated with nifedipine and nimodipine nimodipine (30 mg tid) prophylactic treatment, based on which the observation group used YS7004 brain function treatment and psychological intervention comprehensive treatment. After four weeks treatment, VAS score, headache attack frequency and serum basic fibroblast growth factor (bFGF) concentration in the two groups before and after treatment were evaluated to compare the level of headache, the SAS and the SDS to assess the patient's mental state, compared to the health survey scale (SF-36) to assess the quality of life of patients. Results ①The VAS score, the frequency of headache and the level of serum basic fibroblast growth factor (bFGF) in the two groups were lower than those before treatment, and the decrease rate of the observation group was better than that of the control group, with statistical significance (P<0.01). ②The scores of SAS score and SDS before and after treatment were significantly different from those before treatment (P>0.05). The SAS score and SDS score of the observation group were significantly lower than those before treatment (P<0.01). ③After treatment, SF-36 scores were significantly higher than those before treatment, and the observation group was more significant, showing statistical significance (P<0.01). Conclusion On the basis of routine treatment, combined with brain function therapy instrument and psychological intervention therapy, it has a more significant effect on elderly patients with medication overuse headache, which can relieve headache, improve anxiety and depression, and improve the quality of life of patients. 
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