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A study on various symptoms of chronic hepatitis treated with radix astragali and its regulative effect to levels of serum hormone
Authors:Ke-zhou Liu  Zhong-hang Tong  Ming-tai Zhang  Wei-zheng Gu  Zhi-rong Huang  Bi-he Shen  Pei-ren Cai  Gui-lang Zhu  Wen-nan He  Lan-sheng Feng  Lie-ming Ding  Zhi Chen  Jian-hua Jin  Xiu-zhi Zhang  Qian-yan Yu  Shui-jin Tong and Ping Ye
Affiliation:1. Institute of Infectious Diseases, Zhejiang Medical University, 310003, Hangzhou
2. The First Affiliated Hospital of Zhejiang Medical University, China
3. The Sixth Hospital of Shaoxing, Zhejiang
4. The Hangzhou Railway Hospital, China
5. The Zhejiang Police Hospital, China
6. The Second Hospital of Jiaxing, Zhejiang
Abstract:Sixty-seven cases of chronic hepatitis were treated with Radix Astragali. After treatment (2-month course), the clinical improvement rate in 38 cases of the Stagnation of the Liver-Qi and Deficiency of the Spleen type was 92.1%, and in 26 cases of the Deficiency of Liver Yin and Kidney Yin type was 88.5%, more effective than in the control group (P<0.05). The regulative effect to the levels of serum hormone was observed in the patients of the Stagnation of the Liver-Qi and Deficiency of the Spleen type treated with this medicine. The results showed that the levels of serum triiodothyronine, estradiol (female) and testosterone (male) were increased after treatment (1.40±1.38 ng/dl, 129.30±1.23 pg/ml and 496.24±1.47 ng/dl). Pre-treatment levels were 1.22±1.49 ng/dl, 104.60±1.45 pg/ml and 398. 17±1.55 ng/dl respectively (P<0.05); however, the level of serum prolactin (2.75±4.46 ng/ml) was lower after treatment than before treatment (3.20±3.82 ng/ml,P<0.05). No obvious changes were observed in the levels of serum follicle stimulating hormone, luteinizing hormone, thyroid stimulating hormone, thyroxine, triiodothyronine uptake ratio and cortisol after treatment.
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