| 影响冻融胚胎复苏率和移植成功率因素分析 |
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| 引用本文： | 姚宁,郑菊芬,向祖琼,赵磊文,赵晓明,孙赟,洪燕,陈佩.影响冻融胚胎复苏率和移植成功率因素分析[J].上海交通大学学报(医学版),2009,29(6). |
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| 作者姓名： | 姚宁 郑菊芬 向祖琼 赵磊文 赵晓明 孙赟 洪燕 陈佩 |
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| 作者单位： | 上海交通大学医学院仁济医院生殖医学科,上海200001 |
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| 摘 要： | 目的探讨影响冻融胚胎复苏率和移植成功率的相关因素。方法回顾性分析573个冷冻胚胎移植（FET）周期的临床资料，按冷冻前胚胎质量、胚胎发育时间、解冻后胚胎复苏程度和冷冻方法分别进行分组，分析不同分类各组间的胚胎复苏情况和（或）临床妊娠率差异。结果冷冻当天胚胎中有优质胚胎者的临床妊娠率显著高于无优质胚胎者（31．8％vs20．0％）（P〈0．05）。受精第2天冷冻者与受精第3天冷冻者的胚胎复苏率和临床妊娠率差异无统计学意义（79．1％vs82．9％和25．5％vs31．2％）（P〉0．05）。解冻后完全移植100％卵裂球完整者和混合移植者的临床妊娠率显著高于完全移植部分卵裂球损伤者（36．7％vs24．1％和29．2％vs24．1％）（P〈0．05）。冷冻方法改进后的胚胎复苏率和全胚复苏率显著高于冷冻方法改进前（82．0％vs66．3％和50．0％vs27．5％）（P〈0．05）。结论胚胎质量与胚胎复苏率和临床妊娠率密切相关，冷冻胚胎解冻后全胚复苏率与临床妊娠率正相关，冷冻过程中的操作细节是胚胎实验室保证冻融胚胎复苏、移植成功的重要因素。
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| 关 键 词： | 胚胎冷冻 复苏率 妊娠率 |
Analysis of impact factors for post-thaw embryo survival rate and clinical pregnancy rate of frozen-thawed embryo transfer program |
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| YAO Ning,ZHENG Ju-fen,XIANG Zu-qiong,ZHAO Lei-wen,ZHAO Xiao-ming,SUN Yun,HONG Yan,CHEN Pei.Analysis of impact factors for post-thaw embryo survival rate and clinical pregnancy rate of frozen-thawed embryo transfer program[J].Journal of Shanghai Jiaotong University:Medical Science,2009,29(6). |
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| Authors: | YAO Ning ZHENG Ju-fen XIANG Zu-qiong ZHAO Lei-wen ZHAO Xiao-ming SUN Yun HONG Yan CHEN Pei |
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| Affiliation: | Department of Reproductive Medicine;Renji Hospital;School of Medicine;Shanghai Jiaotong University;Shanghai 200001;China |
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| Abstract: | Objective To explore the impact factors for post-thaw embryo survival rate and clinical pregnancy rate in frozenthawed embryo transfer program.Methods The clinical data of 573 cycles of frozen-thawed embryo transfers were retrospectively analysed.Groups were divided according to the pre-freeze embryo quality,pre-freeze embryonic developmental stage,frozen-thawed embryo quality and cryopreservation technique,respectively,and post-thaw embryo survival rates and/or clinical pregnancy rates were compared among ... |
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| Keywords: | embryo cryopreservation post-thaw embryo survival rate pregnancy rate |
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