| 丹红注射液联合阿托伐他汀钙对急性脑梗死病人血清胱抑素C、同型半胱氨酸及尿酸的影响 |
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| 引用本文： | 宋志友,李从圣,孟令毅,胡承志,群森.丹红注射液联合阿托伐他汀钙对急性脑梗死病人血清胱抑素C、同型半胱氨酸及尿酸的影响[J].蚌埠医学院学报,2022,47(1):33-37. |
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| 作者姓名： | 宋志友 李从圣 孟令毅 胡承志 群森 |
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| 作者单位： | 1.安徽省合肥市滨湖医院 急诊科, 2300002.安徽省立医院 神经内科, 安徽 合肥 230000 |
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| 基金项目： | 安徽省重点研究与开发计划项目(202004j07020014)； |
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| 摘 要： | 目的:探讨丹红注射液联合阿托伐他汀钙对急性脑梗死(ACI)病人血清胱抑素C(Cys-C)、同型半胱胺酸(Hcy)、血尿酸(SUA)水平的影响.方法:选择ACI病人93例,采用随机数字表法分为观察组(47例)和对照组(46例).对照组给予阿托伐他汀钙治疗,观察组给予丹红注射液联合阿托伐他汀钙治疗.治疗14 d,比较2组美...
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| 关 键 词： | 急性脑梗死 丹红注射液 阿托伐他汀钙 胱抑素C 同型半胱氨酸 血尿酸 |
| 收稿时间： | 2020-12-10 |
Effect of Danhong injection combined with atorvastatin calcium on serum cystatin C,homocysteine and uric acid in patients with acute cerebral infarction |
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| SONG Zhi-you,LI Cong-sheng,MENG Ling-yi,HU Cheng-zhi,QUN Sen.Effect of Danhong injection combined with atorvastatin calcium on serum cystatin C,homocysteine and uric acid in patients with acute cerebral infarction[J].Journal of Bengbu Medical College,2022,47(1):33-37. |
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| Authors: | SONG Zhi-you LI Cong-sheng MENG Ling-yi HU Cheng-zhi QUN Sen |
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| Affiliation: | 1.Department of Emergency, Binhu Hospital of Hefei, Hefei Anhui 2300002.Department of Neurology, Anhui Provincial Hospital, Hefei Anhui 230000, China |
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| Abstract: | ObjectiveTo investigate the effects of Danhong injection combined with atorvastatin calcium on serum cystatin C(Cys-C), homocysteine(Hcy) and serum uric acid(SUA) levels in patients with acute cerebral infarction(ACI).MethodsA total of 93 ACI patients were selected and divided into observation group(47 cases) and control group(46 cases) by random number table method.The control group was treated with atorvastatin calcium, and the observation group was treated with Danhong injection combined with atorvastatin calcium.After 14 days of treatment, the reduction rate of the National Institutes of Health stroke scale(NIHSS) score, clinical efficacy, levels of laboratory test indicators(including Cys-C, Hcy and SUA) and the incidence of adverse reactions were compared between the two groups.ResultsAfter treatment, the NIHSS scores in the two groups were significantly lower than those before treatment(P < 0.01);the NIHSS score in observation group were significantly lower than that in control group(P < 0.01), and the reduction rate of NIHSS score and effective rate were higher than those in control group(P < 0.05).After treatment, the levels of Cys-C, Hcy, and SUA in the two groups were significantly lower than those before treatment(P < 0.01), and the levels of Cys-C, Hcy, and SUA in observation group were lower than those in control group(P < 0.05).The incidence of adverse reactions in observation group(6.38%, 3/47) was lower than that in control group(21.74%, 10/46)(P < 0.05).ConclusionsDanhong injection combined with atorvastatin calcium can be helpful to relieve neurological deficits in patients with ACI, improve clinical efficacy, and reduce adverse reactions, which may be related to the reduction of serum Cys-C, Hcy, SUA levels. |
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