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炎症性肠病病人的心理症状及生活质量的相关分析
引用本文:张淑艳,陈立亚,韦成,吴琳,陈春燕,汪芳裕,刘炯.炎症性肠病病人的心理症状及生活质量的相关分析[J].蚌埠医学院学报,2019,44(7):863-867.
作者姓名:张淑艳  陈立亚  韦成  吴琳  陈春燕  汪芳裕  刘炯
作者单位:蚌埠医学院,安徽 蚌埠233030;蚌埠医学院第二附属医院 消化内科,安徽 蚌埠233040;南京军区南京总医院 消化内科,江苏 南京,210002
摘    要:目的调查炎症性肠病(inflammatory bowel disease,IBD)群体的心理症状特点,研究心理症状与生活质量之间的关系,为伴有精神心理异常的IBD病人进行相应的心理治疗提供一定的理论依据。方法收集IBD病人159例和健康人群89名采用一般状况调查表、90项症状清单(SCL-90)量表、炎症性肠病生存质量问卷(IBDQ)与健康调查简表(SF-36)进行心理测评,根据得分进行统计学分析,了解IBD病人的心理症状及对其生活质量的影响。结果与健康人群比较,IBD病人总分、躯体化、抑郁、敌对、偏执及其他方面的阳性率及评分均较高(P < 0.05~P < 0.01);SF-36得分,IBD病人在除精神健康外,其他各维度得分均低于健康人群(P < 0.01);与SCL-90阴性的IBD病人相比,SCL-90阳性的IBD病人在总分、全身、肠道、情感方面得分均较低(P < 0.01);多元线性回归分析显示,IBD病人生活质量的影响因素有(b=27.163,P < 0.01)、忧郁(b=-18.583,P < 0.01)、人际关系敏感(b=17.563,P < 0.05)、偏执(b=-14.316,P < 0.05)。结论IBD病人易合并明显的强迫、人际关系、抑郁、敌对等方面的异常心理症状,生活质量显著降低;生活质量主要受疾病病情、抑郁、人际关系敏感及偏执影响,处于疾病活动期时的病人,抑郁、偏执、人际关系敏感症状重,其生活质量低。

关 键 词:炎症性肠病  心理症状  生活质量
收稿时间:2018-06-19

Correlation analysis between psychological symptoms and quality of life in patients with inflammatory bowel disease
Affiliation:1.Bengbu Medical College, Bengbu Anhui 2330302.Department of Gastroenterdogy, The Second Affiliated Hospital of Bengbu Medical College, Bengbu Anhui 2330403.Department of Nanjing General Hospital of Nanjing Military Region, Nanjing Jiangsu 210002, China
Abstract:ObjectiveTo investigate the characteristics of psychological symptoms in patients with inflammatory bowel disease (IBD) and relationship between psychological symptoms and quality of life, and provide certain theoretical basis for the corresponding psychological treatment of IBD patients with mental and psychological disorder.MethodsThe psychological assessment in 159 patients with IBD and 89 healthy people were implemented using the general status questionnaire, symptom check list-90 (SCL-90) scale, inflammatory bowel disease questionnaire (IBDQ) and MOS item short from health survey (SF-36).The effects of the psychological symptoms of IBD patients on their quality of life were evaluated.ResultsCompared with the healthy people, the total score, and positive rates and scores of somatization, depression, hostility, paranoia and other aspects were higher in IBD patients (P < 0.05 to P < 0.01).The SF-36 score and other dimension scores except for mental health in IBD patients were lower than those in healthy people (P < 0.01).Compared with the SCL-90-negative IBD patients, the total score and scores of whole body, gut and emotions in SCL-90-positive IBD patients were lower (P < 0.01).The results of multiple linear regression analysis showed that the depression, interpersonal sensitivity and paranoia were the influencing factors of the quality of life in patients with IBD (P < 0.05 to P < 0.01).ConclusionsThe IBD patients are prone to be complicated with abnormal psychological symptoms such as compulsion, interpersonal relationship, depression, hostility and low quality of life.The quality of life is mainly affected by illness, depression, interpersonal sensitivity and paranoia.The depression, paranoia and interpersonal sensitivity in patients at active phase of disease are severe, and the quality of life of the patient is low.
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