| 糖尿病肾病中医证型及相关危险因素分析 |
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| 引用本文： | 吴倩,黄帅,杨静静.糖尿病肾病中医证型及相关危险因素分析[J].蚌埠医学院学报,2022,47(7):901-904. |
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| 作者姓名： | 吴倩 黄帅 杨静静 |
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| 作者单位： | 安徽省阜阳市第二人民医院 内分泌科, 236015 |
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| 摘 要： | 目的探讨糖尿病肾病病人主要中医证型的危险因素。方法选取130例糖尿病肾病病人为研究对象, 通过调查问卷采集病人年龄、性别、体质量等一般资料和望闻问切四诊信息, 经专家辨证分型, 分析糖尿病肾病中医证型频次、频率分布, 对临床上常见的糖尿病肾病病人中医证型进行危险因素分析。结果糖尿病肾病中医证侯分布以气阴两虚证(29.23%)、脾肾阳虚证(20.77%)、阴虚燥热证(16.92%)、肝肾阴虚证(13.85%)为主。各中医证型分布频率为: 气阴两虚证>脾肾阳虚证>阴虚燥热证>肝肾阴虚证>脾肾气虚证>瘀毒互结证>阴阳两虚证。不同性别、是否久坐、有无家族史的糖尿病肾病病人中医证型分布差异均无统计学意义(P>0.05), 不同年龄、体质量指数及有无吸烟史和饮酒史糖尿病肾病病人中医证型分布差异均有统计学意义(P < 0.05)。Logistic回归分析结果显示, 糖尿病肾病病人体质量指数、吸烟史和饮酒史是气阴两虚证的危险性因素(P < 0.05~P < 0.01), 年龄、饮酒史是脾肾阳虚证的危险因素(P < 0.01), 体质量指数是阴虚燥热证的危险因素(P < 0.05), 吸烟史是肝肾阴虚证的危险因素(P < 0.05)。结论糖尿病肾病中医证侯分布以气阴两虚证、脾肾阳虚证、阴虚燥热证、肝肾阴虚证为主。糖尿病肾病的中医证型分布与体质量指数、年龄、吸烟史、饮酒史存在一定的相关性。
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| 关 键 词： | 糖尿病肾病 中医证型 危险因素 |
| 收稿时间： | 2021-02-14 |
Analysis of TCM syndrome types and related risk factors of diabetic nephropathy |
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| Affiliation: | Department of Endocrinology, The Second People's Hospital of Fuyang, Fuyang Anhui 236015, China |
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| Abstract: | ObjectiveTo explore the risk factors of the main traditional Chinese medicine(TCM) syndrome types in patients with diabetic nephropathy.MethodsA total of 130 patients with diabetic nephropathy were selected as the research subjects.The age, gender, body mass and other general information of the patients were collected through a questionnaire, and the information of the four diagnostic methods(inspection, auscultation and olfaction, inquiry, pulse-taking and palpation) was collected.The frequency and frequency distribution of TCM syndrome types of diabetic nephropathy were analyzed by expert differentiation of syndromes, and the risk factors of the main TCM syndrome types of diabetic nephropathy patients were analyzed.ResultsThe TCM syndrome types of diabetic nephropathy were mainly Qi-Yin deficiency syndrome(29.23%), spleen-kidney Yang deficiency syndrome(20.77%), Yin deficiency and dry heat syndrome(16.92%), and liver-kidney Yin deficiency syndrome(13.85%).The distribution frequency of each TCM syndrome type was in the following order: Qi-Yin deficiency syndrome >spleen-kidney Yang deficiency syndrome >Yin deficiency and dry heat syndrome >liver-kidney Yin deficiency syndrome > spleen-kidney Qi deficiency syndrome >blood stasis and toxin syndrome >Yin-Yang deficiency syndrome.There was no significant difference in the distribution of TCM syndrome types among diabetic nephropathy patients with different gender, sedentariness or not, and family history or not(P>0.05).There was significant difference in the distribution of TCM syndrome types among patients with different age, body mass index, smoking history and drinking history(P < 0.05).The results of logistic regression analysis showed that body mass index, smoking history and drinking history were the risk factors of Qi-Yin deficiency syndrome(P < 0.05 to P < 0.01), age and drinking history were the risk factors of spleen-kidney Yang deficiency syndrome(P < 0.01), body mass index was the risk factor of Yin deficiency and dry heat syndrome(P < 0.05), and smoking history was the risk factor of liver-kidney Yin deficiency syndrome in patients with diabetic nephropathy(P < 0.05).ConclusionsThe TCM syndrome types of diabetic nephropathy are mainly Qi-Yin deficiency syndrome, spleen-kidney Yang deficiency syndrome, Yin deficiency and dry heat syndrome, and liver-kidney Yin deficiency syndrome.The distribution of TCM syndrome types of diabetic nephropathy is related to body mass index, age, smoking history and drinking history. |
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