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中西医结合治疗慢性肺源性心脏病急性加重期56例
引用本文:吴莹,韦祎.中西医结合治疗慢性肺源性心脏病急性加重期56例[J].中国实验方剂学杂志,2012,18(23):316-319.
作者姓名:吴莹  韦祎
作者单位:1. 海口市琼山区人民医院,海口,570000
2. 海南医学院中医学院,海口,571199
基金项目:海南省教育厅2012年度海南省高等学校科学研究项目(HjKj2012-38)
摘    要:目的:观察中西医结合疗法对慢性肺源性心脏病(CPHD)急性加重期的临床疗效。方法:111例(CPHD)急性加重期患者随机分为观察组56例和对照组55例,两组均予西药常规治疗,观察组加用清金化痰汤合血府逐瘀汤加减口服,每日1剂,疗程12 d。观察两组心功能、肺动脉压、动脉血气分析、血液流变学指标及6 min步行距离的变化。结果:观察组心功能疗效有效率92.85%,优于对照组的72.72%(P<0.05);观察组对肺动脉压、动脉血气分析、血液流变学指标的改善均优于对照组(P<0.01);观察组能明显提高患者6 min步行距离(P<0.01)。结论:中西结合疗法能有效降低CPHD肺动脉压,提高6 min步行距离,降低血黏度,改善患者心肺功能,提高临床疗效。

关 键 词:慢性肺源性心脏病  急性加重期  清金化痰汤  血府逐瘀汤  肺动脉高压  血液流变学  6min步行试验
收稿时间:2012/6/28 0:00:00

Integrative Treatment for 56 Cases of Acute Exacerbation of Chronic Pulmonary Heart Disease
WU Ying and WEI Yi.Integrative Treatment for 56 Cases of Acute Exacerbation of Chronic Pulmonary Heart Disease[J].China Journal of Experimental Traditional Medical Formulae,2012,18(23):316-319.
Authors:WU Ying and WEI Yi
Affiliation:Qiongshan District, Haikou City People's Hospital of Integrated Medicine, Haikou 570000, China;Hainan Medical College, Medical College, Haikou 571199, China
Abstract:Objective: To observe the clinical efficacy of combined Chinese and western medicine therapy on acute exacerbation of chronic pulmonary heart disease (CPHD). Method: One hundred and eleven cases (CPHD) with acute exacerbation were randomly divided into 56 cases of the observation group and 55 cases of control group (western medicine group). Conventional western medicine treatment combined with Qingjin Huatan decoction and Xuefu decoction Tang was applied to the observation group, one a day orally for 12 days. Cardiac function, pulmonary artery pressure, arterial blood gas analysis, hemorheological parameters and 6 minutes walking distance were observed. Result: The efficacy of the cardiac function in the observation group was 92.85%, better than that (72.72%) in the control group (P<0.05). Pulmonary artery pressure, arterial blood gas analysis and hemorheological parameters in the observation group were improved better than those in the control group (P<0.01).The walking distance within 6 minutes in the observation group was longer than that in the control group (P<0.01). Conclusion: Combined Chinese and western medicine therapy can effectively reduce pulmonary artery pressure, increase 6 minutes walking distance, reduce blood viscosity, improve heart and lung function for patients with CPHD, and eventually improve the clinical outcome.
Keywords:chronic pulmonary heart disease  acute exacerbation  Qingjin Huatan decoction  Xuefu Zhuyu decoction  pulmonary hypertension  hemorheology  6 minute walking test
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