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毛茛科植物药用亲缘学的初步探讨
引用本文:彭勇,陈四保,,陈士林,,肖培根.毛茛科植物药用亲缘学的初步探讨[J].中国中药杂志,2006,31(13):1124-1128.
作者姓名:彭勇  陈四保    陈士林    肖培根
作者单位:1. 中国医学科学院,中国协和医科大学,药用植物研究所,北京,100094
2. 中国医学科学院,中国协和医科大学,药用植物研究所,北京,100094;香港理工大学,深圳中药药学及分子药理学重点实验室,广东,深圳,518057
摘    要:目的:探索毛茛科的植物亲缘关系、化学成分与疗效间存在的联系性,即毛茛科药用亲缘学的研究。方法:将有关本草的植物化学、疗效等信息数据与植物亲缘关系进行综合的研究分析。结果:发现本科的化学成分可以划分为几大类型:苄基异喹啉类生物碱,毛茛苷类,三萜皂苷,二萜生物碱等。毛茛苷和木兰碱同时存在于铁线连属Clematis, 铁筷子属Helleborus,驴蹄草属Caltha。结论:结合其疗效,从药用亲缘学的角度来观察,赞同Tamura的主张,将毛茛科划分为6个亚科,即金莲花亚科Helleboroideae、毛茛亚科Ranunculoideae、升麻亚科Cimicifugoideae、扁果草亚科Isopyroideae、唐松草亚科Thalictroideae和黄连亚科Coptidoideae,支持成立升麻亚科的观点。

关 键 词:毛茛科  药用植物亲缘学  化学分类学  系统关系
文章编号:1001-5302(2006)13-1124-05
收稿时间:2006-01-27
修稿时间:2006-01-27

Preliminary pharmaphylogenetic study on Ranunculaceae
PENG Yong;CHEN Si-bao ;;CHEN Shi-lin ; XIAO Pei-gen.Preliminary pharmaphylogenetic study on Ranunculaceae[J].China Journal of Chinese Materia Medica,2006,31(13):1124-1128.
Authors:PENG Yong;CHEN Si-bao ;;CHEN Shi-lin ; XIAO Pei-gen
Affiliation:1. Institute of Medicinal Plant Development, Chinese Academy bf Medical Scienoes, Beijing 100094, China; 2. State Key Laboratory of Pharmaceutical and Molecular Pharmacology of Chinese Medicine, Hong Kong Polytechnic University, Shenzhen 518057, China
Abstract:Objective: To deal with the correlation between phylogeny,chemical constituents and pharmaceutical aspects of Ranunculaceae,namely a pharmaphylogenic study of this taxon.Method: Based on chemical,pharmaceutical(both ethnopharmacologic and pharmacological) information,linking with different plant systems of Ranunculaceae.Result: Chemical constituents of this taxon included several natural groups: benzylisoquinoline alkaloid,ranunculin,triterpenoid glycoside and diterpene alkaloid etc.Ranunculin and magoflorine were found to present simultaneously in some plants of this taxon.Conclusion: Combining with therapeutic information,pharmaphylogenic research were in accordance with the phylogenetic system presented by Tamura that Ranunculaceae was proposed to be divided into six sub-families: Helleboroideae,Ranunculoideae,Cimicifugoideae,Isopyroideae,Thalictroideae and Coptidoideae.Results also supported the establishment of Cimicifugoideae.
Keywords:Ranunculaceae  pharmaphylogeny  chemotaxonomy  phylogenetic relationship
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