| 土贝母化学成分研究 |
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| 引用本文： | 刘文庸,陈伟光,张卫东,陈海生,顾正兵,李廷钊.土贝母化学成分研究[J].中国中药杂志,2004,29(10):953-956. |
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| 作者姓名： | 刘文庸 陈伟光 张卫东 陈海生 顾正兵 李廷钊 |
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| 作者单位： | 1. 第二军医大学,药学院,上海,200433
2. 嘉兴学院,医学院,浙江,嘉兴,314001 |
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| 摘 要： | 目的 :研究中药土贝母的化学成分。方法 :应用硅胶、C18及SephadexLH-20柱色谱分离 ,物理、化学方法及光谱 (IR ,MS ,1H NMR ,13C NMR ,2DNMR)分析技术鉴定结构。结果 :分离并鉴定了 8个化合物 ,分别为麦芽酚(Ⅰ) ,大黄素 (Ⅱ) ,葫芦素B(Ⅲ ) ,葫芦素E(Ⅳ ) ,Δ7,22 ,25 豆甾三烯 3 醇 (Ⅴ ) ,Δ7,22 ,25 豆甾三烯醇 3O 十九烷酸酯(Ⅵ) ,Δ7,22 ,25 豆甾三烯醇-3-O-β-D-吡喃葡萄糖苷 (Ⅶ )与Δ7,22 ,25 豆甾三烯醇-3-O-β-D-(6′-棕榈酰基 )吡喃葡萄糖苷(Ⅷ )。结论 :化合物Ⅱ～Ⅷ为首次从该植物中分离得到 ,其中化合物Ⅵ ,Ⅷ为新化合物。
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| 关 键 词： | 土贝母 葫芦素 甾醇 |
| 文章编号： | 1001-5302(2004)10-0953-04 |
| 收稿时间： | 2003/2/15 0:00:00 |
Studies on chemical constituents in bulbs of Bolbostemma paniculatum |
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| LIU Wen-yong ;CHEN Wei-guang ;ZHANG Wei-dong ;CHEN Hai-s heng ;GU Zheng-bing ;LI Ting-zhao.Studies on chemical constituents in bulbs of Bolbostemma paniculatum[J].China Journal of Chinese Materia Medica,2004,29(10):953-956. |
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| Authors: | LIU Wen-yong ;CHEN Wei-guang ;ZHANG Wei-dong ;CHEN Hai-s heng ;GU Zheng-bing ;LI Ting-zhao |
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| Affiliation: | College of Pharmacy, Second Military Medical University, Shanghai 200433, China. |
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| Abstract: | OBJECTIVE: To investigate the chemical constituents of the bulbs of Bolbostemma panicultum. METHOD: The compounds were isolated by column chromatography on silica gel, C18, Sephadex LH-20 separately and their structures were elucidated by chemical and spectroscopic technologies. RESULT: Eight compounds were isolated and identified as maltol(I), emodin(II), cucurbitacin B(III), cucurbitacin E(IV), stigmasta-7, 22, 25-triene-3-ol(V), stigmasta-7, 22, 25-triene-3-nonadecanoic acid ester(VI), stigmasta-7, 22, 25-triene-3-O-beta-D-glucopyranoside(VII), stigmasta-7, 22, 25-triene-3-O-beta-D-(6'-palmitoyl) glucopyranoside(VIII). CONCLUSION: I-VIII were obtained from this plant for the first time; VI and VIII are new compounds. |
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| Keywords: | Bolbostemma paniculatum cucurbitacin steroloids |
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