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当归挥发油研究新进展
引用本文:杜俊蓉,白波,余彦,汪程远,钱忠明.当归挥发油研究新进展[J].中国中药杂志,2005,30(18):1400-1406.
作者姓名:杜俊蓉  白波  余彦  汪程远  钱忠明
作者单位:1. 香港理工大学,应用生物及化学科技学系,香港,九龙
2. 四川大学,华西药学院,四川,成都,610041
3. 香港理工大学,应用生物及化学科技学系,香港,九龙;首都医科大学药学院,北京,100054
摘    要:对当归挥发油提取、化学成分分析鉴定、药理作用以及临床应用等新进展做一综述。以当归挥发油为关键词检索了1994~2004年CNKI(中国学术期刊数据库)、1997~2004年Medline(美国国立医学图书数据库),并对相关的参考文献进行追踪检索。归纳、比较了多种当归挥发油的提取方法及化学成分分析、鉴定方法。对当归挥发油药理作用的多项研究报告进行了总结,包括当归挥发油毒性、对子宫平滑肌、心血管系统、呼吸系统、中枢神经系统、免疫系统的影响及其临床应用。常见的当归挥发油提取方法有3种,不同提取方法下挥发油的收率不同。其化学成分复杂,研究者不断分离得到新的化学成分。当归挥发油对子宫平滑肌具有双向作用,能够抑制多种机制引起的子宫平滑肌收缩。当归挥发油能够降低血压、改善心肌缺血,抗心率失常。并且具有平喘、抑制中枢神经系统、提高机体免疫功能及抗炎镇痛等药理作用。目前当归挥发油主要应用于痛经及月经不调的治疗。当归挥发油化学成分复杂、药理作用广泛,对当归挥发油的研究不断取得新近展。

关 键 词:当归挥发油  研究新进展
文章编号:1001-5302(2005)18-1400-07
收稿时间:2005-04-10
修稿时间:2005-04-10

The new progress of the study about volatile oil of the angelica
DU Jun- rong;BAI Bo;YU Yan;WANG Cheng-yuan;QIAN Zhong-ming.The new progress of the study about volatile oil of the angelica[J].China Journal of Chinese Materia Medica,2005,30(18):1400-1406.
Authors:DU Jun- rong;BAI Bo;YU Yan;WANG Cheng-yuan;QIAN Zhong-ming
Affiliation:1. Department of Applied Biology and Chemistry, The Hong Kong Polytechnic University, Hong Kong , China; 2. Department of Pharmacology, West China School of Pharmacy Sichuan University, Chengdu 610041, China; 3. Department of Pharmacology, Capital University of Medical Sciences, Beijing 100054, China
Abstract:To summarize the new progress of the study about volatile oil of the angelica, including the distillable methods, the analysis of the chemical components, the pharmacological effects and the clinical applications. We tracked and searched the correlative references and study reports about volatile oil of the angelica in CNKI data base(1994-2004) and Medline data base (1997-2004). We summarized and compared the different distillable methods of volatile oil of the angelica, meanwhile we summarized many study reports about the analysis of the chemical components of volatile oil of the angelica and it's pharmacological effects, including the toxicity of the volatile oil and it's effects on the uterus smooth muscle, cardiovascular system, respiratory system, central nerve system and immune system. Finally we summarized the clinical application of the volatile oil of the angelica. There are three distillable methods of volatile oil of the angelica . The harvest efficiency of volatile oil is different with different distillable methods. The chemical components are very complicated and the new chemical components are separated and identified. The volatile oil has bidirectional effects on the uterus smooth muscle. It can inhibit the contraction of the uterus smooth muscle induced by different mechanisms. Meanwhile it can depress the blood pressure and ameliorate the cardiac ischemia. The volatile oil can resist the arrhythmia and asthma, restrain the central system, improve the immune function. Nowadays the volatile oil of the angelica is applied to therapy the dysmenorrhea and disorder of the catamenia. The chemical components of the volatile oil of the angelica are very complicated, moreover the pharmacological effects of the volatile oil are comprehensive. People make the new progress of the study about volatile oil of the angelica.
Keywords:the volatile oil of the angelica  new progress
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