| 纳米药物载体在中药制剂研发中的应用 |
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| 引用本文： | 易承学,余江南,徐希明.纳米药物载体在中药制剂研发中的应用[J].中国中药杂志,2008,33(16):1936-1940. |
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| 作者姓名： | 易承学 余江南 徐希明 |
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| 作者单位： | 江苏大学药学院,江苏,镇江,212013 |
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| 基金项目： | 国家自然科学基金，镇江市产学研科技合作项目 |
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| 摘 要： | 纳米药物载体通常由天然或合成高分子材料制成，大小在10～1 000 nm ，因其具有靶向性、缓释性、载体材料可生物相容和降解等显著优点，已在药物制剂研发中得到广泛应用。近年来，中药纳米制剂发展迅速，作者通过查阅国内外文献，重点围绕毫微粒、脂质纳米粒、纳米乳、纳米胶束、纳米脂质体等几种典型的纳米载体的特性、制备及其在中药制剂研发中的应用进行综述。
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| 关 键 词： | 纳米药物载体 中药 应用 制备方法 |
| 收稿时间： | 2008/4/10 0:00:00 |
Nanoscale drug carriers for traditional Chinese medicine research and development |
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| YI Cheng-xue; YU Jiang-nan; XU Xi-ming.Nanoscale drug carriers for traditional Chinese medicine research and development[J].China Journal of Chinese Materia Medica,2008,33(16):1936-1940. |
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| Authors: | YI Cheng-xue; YU Jiang-nan; XU Xi-ming |
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| Abstract: | Nanocarriers generally made of natural or artificial polymers ranging in size from about 10-1 000 nm, possess versatile properties suitable for drug delivery, including good biocompatibility and biodegradability, potential capability of targeted delivery and controlled release of incorporated drugs, and have been extensively used in the development of new drug delivery systems (DDS). These types of nano-DDS have considerable potential to traditional Chinese medicine (TCM), and recently have attracted increasing efforts on the TCM research and development. In this review, the recently published literature worldwide is covered to describe the latest advances in the applications as TCM delivery carriers, and to highlight the characteristics and preparation methods of some selected examples of promising nanocarriers such as nanoparticles, lipid nanoparticles, nanoemulsions, nanomicelles and nanoliposomes. |
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| Keywords: | nanocarriers for drug delivery traditional Chinese medicine application production methods |
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