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| 代谢组学在中医药复杂理论体系研究中的应用 | |
| 引用本文： | 贾伟,蒋健,刘平,赵立平,陈闽军,周明眉,杨丽萍,王米渠,邱明丰,张永煜.代谢组学在中医药复杂理论体系研究中的应用[J].中国中药杂志,2006,31(8):621-624. |
| 作者姓名： | 贾伟 蒋健 刘平 赵立平 陈闽军 周明眉 杨丽萍 王米渠 邱明丰 张永煜 |
| 作者单位： | 1. 上海交通大学,上海系统生物学研究所,上海,200030 2. 上海中医药大学,上海,201203 3. 成都中医药大学,四川,成都,610075 |
| 摘 要： | 新兴学科代谢组学的出现,给中医药复杂理论体系的研究、中医药现代化提供了强有力的研究手段。中医病证引起代谢物组的共性分析和生物标记物的发现,可促进“证”本质的研究、中医辨证的科学化和定量化,深层次理解中医脏象理论,预测疾病的发生,整体性评价中药复方综合疗效、安全性和作用机制,反应肠道内生态环境状况。代谢组学和中医药学的结合,将探索出中医药复杂理论体系研究的新方法与新途径。 |
| 关 键 词： | 代谢组学 中医药复杂理论系统 辨证论治 脏象理论 中药方剂 肠道菌群微生态学 |
| 文章编号： | 1001-5302（2006）08-0621-04 |
| 收稿时间： | 2005-02-10 |
| 修稿时间： | 2005-02-10 |
Application of metabonomics in complicated theory system research of traditional Chinese medicine |
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| JIA Wei,;LIU Ping,;JIANG Jian,;CHEN Min-jun,;ZHAO Li-ping,;ZHOU Ming-mei,;YANG Li-ping,;WANG Mi-qu,;QIU Mingfeng,;ZHANG Yong-yu.Application of metabonomics in complicated theory system research of traditional Chinese medicine[J].China Journal of Chinese Materia Medica,2006,31(8):621-624. | |
| Authors: | JIA Wei ;LIU Ping ;JIANG Jian ;CHEN Min-jun ;ZHAO Li-ping ;ZHOU Ming-mei ;YANG Li-ping ;WANG Mi-qu ;QIU Mingfeng ;ZHANG Yong-yu |
| Affiliation: | 1. Sianghai Institute for System Biology, Shanghai Jiao Tong University, Shanghai 200030, China ; 2. Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China 3. Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China |
| Abstract: | Metabonomics,a new and rapid-developing technology,will be powerful means to the research of complexed theory system and modernization of traditional Chinese medicine(TCM).Discovery of biomarkers and analysis of common properties from the metabolome of a specific TCM syndrome will facilitate the modernized study of TCM system,promote the quantitative and scientific elucidation of TCM syndrome differentiation,provide an in-depth understanding of the TCM theory of Zang-xiang,help predict the disease on-set,and achieve a comprehensive evaluation of systemic clinical efficacy,safety and mechanism of action of the TCM combination formulas along with a better understanding of intestinal microflora ecology.The new approach with combined metabonomics and TCM methodologies will provide a new pathway and methodology for the study of complicated theory system of TCM and its modernization. |
| Keywords: | metabonomics complexed theory system of TCM treatment based on syndrome differentiation Zang-xiang theory intestinal microflora ecology |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |
