| 丹参护肝机理的研究 |
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| 引用本文： | 邓和军,马学惠,许瑞龄,陈贤明,赵元昌,尹镭,韩.丹参护肝机理的研究[J].中国中药杂志,1992,17(4):233-236. |
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| 作者姓名： | 邓和军 马学惠 许瑞龄 陈贤明 赵元昌 尹镭 韩 |
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| 作者单位： | 山西医学院太原,030001 |
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| 摘 要： | 实验结果表明,丹参能明显抑制正常及损伤肝细胞脂质过氧化反应,诱导细胞色素P450的合成,防止损伤肝细胞蛋白质、DNA、RNA、尿素及铜兰蛋白的降低,减轻肝毒物对体外培养肝细胞超微结构的损伤。
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| 关 键 词： | 肝脏 丹参 脂质过氧化作用 |
| 收稿时间： | 8/3/1990 12:00:00 AM |
Studies on Mechanisms of Protective Action of Radix Salviae Miltiorrhizae (RSM) against Experimental Hepatic Injury in Rats |
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| Deng Hejun,Ma Xuehui,Xu Ruilin,Chen Xianmin Zhao Yuanchang,Yin Lei and Han Dewu.Studies on Mechanisms of Protective Action of Radix Salviae Miltiorrhizae (RSM) against Experimental Hepatic Injury in Rats[J].China Journal of Chinese Materia Medica,1992,17(4):233-236. |
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| Authors: | Deng Hejun Ma Xuehui Xu Ruilin Chen Xianmin Zhao Yuanchang Yin Lei and Han Dewu |
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| Abstract: | The results indicated that RSM could significantly inhibit the lipid peroxidation of normal livers and cultured hcpatocytes of rats, induce liver microsomal cytochrome P450 in normal rats, increase nucleic acids, proteins, urea and cerolloplasmin of damaged cultured hepatocytes of rats, relieve ultrastructural damage of cultured hepatocytes induced by CCl4. The pharmacological actions mentioned above should be considered as important mechanisms of RSM against liver iniury. |
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| Keywords: | liver Radix Salviae Miltiorrhizae lipid peroxidation |
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