血府逐瘀浓缩丸防治43例冠心病冠脉内支架植入术后再狭?… |
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引用本文: | 于蓓,毛节明.血府逐瘀浓缩丸防治43例冠心病冠脉内支架植入术后再狭?…[J].中国中西医结合杂志,1998,18(10):585-589. |
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作者姓名: | 于蓓 毛节明 |
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作者单位: | 中国中医研究院西苑医院!北京100091(于蓓,陈可冀),北京医科大学第三临床医学院(毛节明,郭静萱),首都医科大学附属北京安贞医院(吕树铮) |
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基金项目: | 国家科委“八五”攻关课题 |
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摘 要: | 探讨血府逐瘀浓缩丸防治冠心病冠脉内支架植入术后再狭窄的临床疗效。方法:将84例冠脉内支架植入术成功的冠心病患者随机分为西药常规治疗和加血府逐瘀浓缩丸组和西药常规治疗组,疗程均为6个月。追踪观察患者有无心绞痛复发,以及患者的血瘀症状和血瘀证候积分的变化,并通过心电图活动平板运动试验,运动-静息心肌断层是像追踪,冠状动脉造影复查评价再狭窄的发生。
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关 键 词: | 冠心病 冠脉内 支架植入 再狭窄 血腐逐瘀浓缩丸 |
Clinical Study on Effect of Concentrated Xuefu Zhuyu Pill on Restenosis of 43 Cases Coronary Heart Disease after Intracoronary Stenting |
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Authors: | Yu Bei Chen Keji Mao Jieming Xiyuan Hospital China Academy of TCM Beijing |
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Abstract: | Objective: To explore the clinical effectiveness of concentrated Xuefu Zhuyu Pill (CXZP) on restenosis (RS) of coronary heart disease (CHD) after intracoronary stenting. Methods: Eighty four successful intracoronary stenting patients were randomly divided into conventional treatment group ( control group, 41 cases) and conventional treatment plus CXZP group (treated group, 43 cases). The follow up underwent for 6 months. Clinical symptom, change of blood stasis were observed. And occurrence of restenosis was estimated by ECG exercise treadmill testing, emission computed tomography (ECT) and coronary angiography (CAG). Results: The symptoms of blood stasis of treated group improved in the follow up significantly (P<0 01), and the integral of blood stasis were decreased significantly in the treated group vs the conventional treatment group (P<0 01). The recurrent angina pectoris rate of the treated group was lower than the conventional treatment group (P<0 01). The 61.9% of 84 patients reexamined the CAG in the follow up, and the lower restenosis rate (25.8%) in the treated group than in the conventional treatment group (32.1%,P=0.59). Conclusion: There is the trend that CXZP could prevent restenosis. Therefore, it is necessary to increase the cases for further study of CXZP on preventing restenosis. |
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Keywords: | coronary heart disease percutaneous transluminal coronary angioplasty intracoronary stenting restenosis concentrated Xuefu Zhuyu pill |
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