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Graft loss attributed to possible transfusion‐transmitted ehrlichiosis following cord blood stem cell transplant
Authors:Allison Mah  George M Viola  Ella Ariza Heredia  Katayoun Rezvani  Partow Kebriaei  Micah M Bhatti  Xin Han  Elizabeth J Shpall  Victor E Mulanovich
Affiliation:1. Division of Infectious Diseases, Department of Medicine, University of British Columbia, Vancouver, BC, Canada;2. Department of Infectious Diseases, Infection Control and Employee Health, Division of Internal Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA;3. Department of Stem Cell Transplantation and Cellular Therapy, Division of Cancer Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA;4. Department of Laboratory Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA
Abstract:We present a case of possible transfusion‐transmitted Ehrlichia chaffeensis infection in a heavily transfused cord blood transplant recipient, resulting in severe infection and graft loss. Transfusion‐transmitted, vector‐borne infections in immunocompromised individuals can have severe consequences, and should be considered in hospitalized patients receiving blood products with unexplained fever or sepsis.
Keywords:blood banks  cord blood transplant     Ehrlichia chaffeensis     ehrlichiosis  sepsis
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