| 2018—2021年成都市非EV - A71感染手足口病患者住院费用及其影响因素研究 |
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| 引用本文： | 任雪玲,雷博文,张璐,申雨珂,张德蓝,曾义岚,张朝勇,王筱,彭红霞,唐雪琴,段晓霞,杨艳芳,龙璐.2018—2021年成都市非EV - A71感染手足口病患者住院费用及其影响因素研究[J].现代预防医学,2022,0(18):3326-3331. |
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| 作者姓名： | 任雪玲 雷博文 张璐 申雨珂 张德蓝 曾义岚 张朝勇 王筱 彭红霞 唐雪琴 段晓霞 杨艳芳 龙璐 |
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| 作者单位： | 1. 四川大学华西公共卫生学院/华西第四医院，四川 成都 610041；2. 成都市公共卫生临床医疗中心 |
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| 摘 要： | 目的 了解成都市非EV - A71手足口病患者住院费用及其影响因素。方法 通过成都市公共卫生临床中心病案管理系统，收集2018—2021年手足口病住院病人信息。采用秩和检验、多元线性回归分析不同血清型患者费用的影响因素。结果 共纳入2 310例手足口病患者，直接医疗费用中位数为4 187元。秩和检验结果显示，CV - A10患者的住院天数、重症的费用差异有统计学意义（U = - 4.40, - 3.59； P＜0.05）；CV - A16患者的住院天数、高热的费用差异有统计学意义（U = - 4.90, - 2.51； P＜0.05）；CV - A6患者的性别、住院天数、并发症、重症、支付方式的费用差异有统计学意义（U = - 2.81, - 13.54, - 4.00, - 4.28；H = 13.65； P＜0.05）；其他肠道病毒患者的住院天数、并发症、重症、支付方式的费用差异有统计学意义（U = - 7.46, - 3.25, - 2.45；H = 13.14；P＜0.05）；混合感染患者高热的费用差异有统计学意义（U = - 2.40, P＜0.05）。多元线性回归结果显示，除混合感染外，住院天数是所有患者费用的影响因素。在CV - A10、CV - A6和其他肠道病毒中重症患者的费用更高；在CV - A6和其他肠道病毒中有并发症的患者费用更高。高热是混合感染患者费用的影响因素。结论 成都市非EV - A71感染手足口病患者的病毒血清型不同，费用的影响因素也有所不同。
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| 关 键 词： | 手足口病 住院费用 多元线性回归 |
Hospitalization costs and influencing factors of hand,foot and mouth disease with non-EV-A71 infection in Chengdu, 2018—2021 |
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| REN Xue-ling,LEI Bo-wen,ZHANG Lu,SHEN Yu-ke,ZHANG De-lan,ZENG Yi-lan,ZHANG Chao-yong,WANG Xiao,PENG Hong-xia,TANG Xue-qin,DUAN Xiao-xia,YANG Yan-fang,LONG Lu.Hospitalization costs and influencing factors of hand,foot and mouth disease with non-EV-A71 infection in Chengdu, 2018—2021[J].Modern Preventive Medicine,2022,0(18):3326-3331. |
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| Authors: | REN Xue-ling LEI Bo-wen ZHANG Lu SHEN Yu-ke ZHANG De-lan ZENG Yi-lan ZHANG Chao-yong WANG Xiao PENG Hong-xia TANG Xue-qin DUAN Xiao-xia YANG Yan-fang LONG Lu |
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| Affiliation: | *West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan 610041, China |
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| Abstract: | Objective To investigate the hospitalization costs of hand, foot and mouth disease (HFMD) patients with non-EV-A71 infection in Chengdu and its influencing factors. Methods The data of inpatients with HFMD from 2018 to 2021 were collected through the medical record management system of Chengdu Public Health Clinical Center. Rank sum test and multiple linear regression were used to analyze the factors influencing the cost of patients with different serotypes. Results A total of 2 310 patients with HFMD were enrolled, and the median direct medical cost was 4 187 yuan. The results of the rank sum test showed that there were statistically significant differences in costs for days of hospitalization and serious illness in patients with CV-A10 (U values of -4.40 and -3.59, P<0.05, respectively), days of hospitalization and high fever in patients with CV-A16 (U values of -4.90 and -2.51, P<0.05, respectively), and gender, days of hospitalization, complications, severe illness, and payment in patients with CV-A6 (U values -2.81, -13.54, -4.00, and -4.28, H=13.65, P<0.05, respectively). Other patients with enterovirus had statistically significant differences in days in hospital, complications, serious illness, and payment method (U values -7.46, -3.25, and -2.45, H=13.14, P<0.05). The difference in costs for hyperthermia in patients with mixed infections was statistically significant (U=-2.40, P<0.05). Multiple linear regression results showed that the number of hospital days was an influencing factor in the cost of all patients except for mixed infections. Costs were higher in patients with severe disease in CV-A10, CV-A6, and other enteroviruses, and costs were higher in patients with complications in CV-A6 and other enteroviruses. Hyperthermia was an influencing factor in the cost of patients with mixed infections. Conclusion The influencing factors of cost differ among virus serotypes of non-EV-A71 infected HFMD patients in Chengdu. |
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| Keywords: | Hand foot and mouth disease Hospitalization costs Multiple linear regression |
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