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生命早期1000天绿地暴露与幼儿睡眠关系队列研究
引用本文:吴输,谢路勤,陈宇靖,吴生池,静进,董光辉,林力孜,蔡莉.生命早期1000天绿地暴露与幼儿睡眠关系队列研究[J].中华疾病控制杂志,2022,26(2):200-205.
作者姓名:吴输  谢路勤  陈宇靖  吴生池  静进  董光辉  林力孜  蔡莉
作者单位:1.510080 广州,中山大学公共卫生学院妇幼卫生学系
基金项目:广东省重点领域研发计划项目
摘    要:目的 探究生命早期1000d绿地暴露与2岁幼儿睡眠之间的关联性.方法 采用前瞻性队列研究设计,抽取在广州市某区妇幼保健院产检的孕妇,在妊娠20~28周时收集有关的基线信息,并且在生命早期1000d,从基于母亲居住地的遥感卫星数据中提取具有不同半径区域(250 m和500 m)的归一化植被指数(normalized di...

关 键 词:幼儿  睡眠  绿地暴露  生命早期
收稿时间:2021-06-16

The relationship between residential greenness in the first 1000 days of life and sleep in toddlers:a cohort study
WU Shu,XIE Lu-qin,CHEN Yu-jing,WU Sheng-chi,JING Jin,DONG Guang-hui,LIN Li-zi,CAI Li.The relationship between residential greenness in the first 1000 days of life and sleep in toddlers:a cohort study[J].Chinese Journal of Disease Control & Prevention,2022,26(2):200-205.
Authors:WU Shu  XIE Lu-qin  CHEN Yu-jing  WU Sheng-chi  JING Jin  DONG Guang-hui  LIN Li-zi  CAI Li
Affiliation:1.Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China2.Department of Occupational Health and Environmental Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China
Abstract:Objective To explore the association between residential greenness in the first 1 000 days of life and sleep problems in 2-year toddlers. Methods A prospective cohort study was conducted, from which we selected pregnant women who underwent prenatal examination in a Maternal and Child Health Hospital in Guangzhou. We have collected baseline information at 20-28 weeks of pregnancy. We also calculated normalized difference vegetation index(NDVI) with different buffers(250 m and 500 m) from remote satellite data based on maternal residential addresses to assess the level of residential greenness in the first 1 000 days of life. During the follow-up visits, we collected sleep outcomes during the last months of 2-year toddlers using the Chinese version of the brief infant sleep questionnaire. Logistic regression model and multiple linear regression model were performed to evaluate the association of residential greenness with sleep quality and sleep time, respectively. Results A total of 410 mother-toddler pairs were included, and the average daily sleep time of 2-year toddlers was 12.27 hours. The proportion of sleep quality problem was 39.27%, among which the highest was nocturnal awaking(16.83%), followed by difficulty to fall asleep(15.61%) and irregular sleep(13.41%). In the analyses of Logistic regression, the results indicated null associations of residential greenness in the first 1 000 days of life with the occurrence of difficulty to fall asleep, nocturnal awaking, irregular sleep, or any of the above sleep quality problems in 2-year toddlers(OR=0.77, 95% CI=0.39-1.54, P=0.465;OR=1.30, 95% CI=0.66-2.55, P=0.453;OR=0.87, 95% CI=0.40-1.88, P=0.714;OR=1.21, 95% CI=0.72-2.03, P=0.464). In the analyses of multiple linear regressions, the results indicated null associations between greenness exposure and sleep time at night, sleep time during daytime, and total sleep time in two-year-old toddlers(β±SE=-0.04±0.11, P=0.715;β±SE=-0.01±0.08, P=0.957;β±SE=-0.04±0.12, P=0.726). Conclusion No significant associations are found between residential greenness in the first 1 000 days of life and sleep quality problems and sleep time in 2-year toddlers.
Keywords:Toddler  Sleep  Residential greenness  The first 1000 days
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