| 胃癌患者术前贫血与术后并发症及预后的相关性 |
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| 引用本文： | 张文明,陆春雷,李科军,刘书尚,丰帆,郭曼,张洪伟.胃癌患者术前贫血与术后并发症及预后的相关性[J].现代肿瘤医学,2021,0(7):1183-1187. |
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| 作者姓名： | 张文明 陆春雷 李科军 刘书尚 丰帆 郭曼 张洪伟 |
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| 作者单位： | 1.空军军医大学西京医院消化外科，陕西 西安 710032;
2.临夏州人民医院普外科，甘肃 临夏 731100;
3.无锡眀慈医院消化病中心，江苏 无锡 214000 |
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| 基金项目： | 国家自然科学基金(编号:81772937,81672742)。 |
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| 摘 要： | 目的:探讨术前贫血和贫血程度与胃癌并发症及预后的关系。方法:对2008年10月至2016年11月期间空军军医大学西京医院消化外科3 692例行胃癌根治术患者的临床资料进行分析。探索术前贫血和贫血程度对胃癌术后并发症和预后的影响。结果:3 692例患者中，男性2 889例(78.3%)，女性803例(21.7%)。贫血患者1 493例(40.4%)，年龄20~86岁，中位年龄58.5岁。术前贫血组年龄、性别、肿瘤部位、肿瘤大小、分化程度和T分期、N分期、TNM分期与术前未贫血组存在显著差异(P＜0.05)。术前贫血组患者术后发热的发生率明显增高(P＜0.05)。单因素分析结果显示，年龄、肿瘤大小、分化程度、T分期、N分期、TNM分期、术前贫血是影响胃癌预后的危险因素(P＜0.05)。多因素分析结果显示，术前贫血是影响胃癌预后的独立危险因素(HR=1.141，95%CI:1.018~1.280,P=0.024)。在术前贫血组内，轻度、中度、重度贫血患者的生存无明显差异。结论:胃癌患者术前贫血会增加术后发热的发生率，术前贫血是影响胃癌预后的独立危险因素。
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| 关 键 词： | 胃癌 贫血 预后 并发症 |
Correlation between pre-operative anemia and postoperative complications and prognosis in gastric cancer patients |
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| ZHANG Wenming,LU Chunlei,LI Kejun,LIU Shushang,FENG Fan,GUO Man,ZHANG Hongwei.Correlation between pre-operative anemia and postoperative complications and prognosis in gastric cancer patients[J].Journal of Modern Oncology,2021,0(7):1183-1187. |
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| Authors: | ZHANG Wenming LU Chunlei LI Kejun LIU Shushang FENG Fan GUO Man ZHANG Hongwei |
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| Affiliation: | 1.Department of Digestive Surgery,Xijing Hospital,the Air Force Military Medical University,Shaanxi Xi'an 710032,China;2.Department of General Surgery,Linxia People's Hospital,Gansu Linxia 731100,China;3.Center of Digestive Disease,Wuxi Mingci Hospital,Jiangsu Wuxi 214000,China. |
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| Abstract: | Objective:To analyze the association between pre-operative anemia and degree of anemia with the postoperative complications and prognosis of gastric cancer.Methods:From October 2008 to November 2016,3692 gastric cancer patients treated with radicalgastrectomy were enrolled in the present study.The association betweenpre-operative anemia and degree of anemia with postoperative complications and prognosis of gastric cancer and survival of patients were analysed.Results:There were 2889 males(78.3%)and 803 females(21.7%).The median age was 58.5 years(range 20~86 years old).The anemia group included 1493 patients(40.4%).Age,gender,tumor location,tumor size,differentiation status,T stage,N stage and TNM stage showed statistically significant differences between the anemia group and the non-anemia group(all P<0.05).The anemia group was associated with increased postoperative fever(P<0.05).Univariate analysis showed that age,tumor size,differentiation status,T stage,N stage,TNM stage and pre-operative anemia were risk factors for the prognosis of patients(all P<0.05).Multivariateanalysis showed that pre-operative anemia was independently associated with poor prognosis of patients(HR=1.141,95%CI:1.018~1.280,P=0.024).Conclusion:Pre-operative anemia was associated with postoperative fever.Pre-operative anemia was associated with poor prognosis of gastric cancer patients. |
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| Keywords: | gastric cancer anemia prognosis complications |
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