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妇科肿瘤患者医院感染病原菌分布及耐药性分析
引用本文:慕玉东,郝妮娜,张 涛,代 佳,袁志敏,刘斯扬,李 林.妇科肿瘤患者医院感染病原菌分布及耐药性分析[J].现代肿瘤医学,2018,0(10):1585-1587.
作者姓名:慕玉东  郝妮娜  张 涛  代 佳  袁志敏  刘斯扬  李 林
作者单位:1.陕西省肿瘤医院,陕西 西安 710061;2.西安市中心医院心内科,陕西 西安 710003
基金项目:陕西省社会发展科技攻关项目(编号:2016SF-229); 陕西省中医管理局中医药科研项目(编号:LCPT038)
摘    要:目的:对妇科肿瘤患者医院感染病原菌的分布特点及耐药性进行分析,为临床治疗提供依据。方法:回顾性分析2010年1月至2017年7月住院治疗的妇科肿瘤患者851例,对其感染的病原菌分布及药敏进行分析统计。结果:发生医院感染72例,感染率为8.46%;共检出83株病原菌,革兰阴性菌(57株)占68.68%,革兰阳性菌(21株)占25.30%,真菌(5株)占6.02%;大肠埃希菌对头孢唑林及氨苄西林的耐药率较高,铜绿假单胞菌对氨苄西林、头孢唑林、复方新诺明的耐药率较高,金黄色葡萄球菌对青霉素、红霉素的耐药率较高。结论:妇科肿瘤患者医院感染以革兰氏阴性杆菌为主,革兰氏阳性菌次之,细菌耐药现象严重,临床上要根据药敏结果合理选用抗菌药物,有效提高疗效。

关 键 词:妇科  肿瘤  医院感染  病原菌  耐药性

Analysis on bacteriological spectrum and drug resistance of nosocomial infections in patients with gynecologic tumor
Mu Yudong,Hao Nina,Zhang Tao,Dai Jia,Yuan Zhimin,Liu Siyang,Li Lin.Analysis on bacteriological spectrum and drug resistance of nosocomial infections in patients with gynecologic tumor[J].Journal of Modern Oncology,2018,0(10):1585-1587.
Authors:Mu Yudong  Hao Nina  Zhang Tao  Dai Jia  Yuan Zhimin  Liu Siyang  Li Lin
Affiliation:1.Shaanxi Provincial Cancer Hospital,Shaanxi Xi'an 710061,China;2.Department of Cardiology,Xi'an Central Hospital,Shaanxi Xi'an 710003,China.
Abstract:Objective:To analyze distribution characteristics and drug resistance of nosocomial infection pathogen of patients with gynecological tumors.Methods:851 patients with gynecological tumors who were admitted to our hospital from January 2010 to July 2017 were retrospectively analyzed.Results:The nosocomial infections occurred in 72 cases with the infection rate of 8.46%,83 strains pathogenic bacteria were detected,including 57(68.68%)srains of gram-negative bacteria,21(25.30%)strains of gram-positive bacteria,and 5(6.02%)strains of fungi.Escherichia coli were of the higher resistant rate for cefazolin and ampicillin,pseudomonas aeruginosa were of the higher resistant rate for ampicillin,cefazolin and trimethoprim,staphylococcus aureus were of the higher resistant rate for penicillin and erthrocin.Conclusion:Nosocomial infections of patients with gynecological tumos were mainly are gram-negative bacteria followed by gram-positive bacteria,and the drug resistance of bacteria is more serious.It is necessary to reasonably use broad spectrum antibiotics in line with the antibacterial spectrum to improve the therapentic effect.
Keywords:department of gynecology  tumor  nosocomial infection  pathogens  drug resistance
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