| TACE联合体部伽玛刀治疗巨块型肝癌的临床观察 |
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| 引用本文： | 蔡薇薇,苏加利,杨 妤,朱道奇,刘利民,黄高明.TACE联合体部伽玛刀治疗巨块型肝癌的临床观察[J].现代肿瘤医学,2018,0(8):1236-1239. |
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| 作者姓名： | 蔡薇薇 苏加利 杨 妤 朱道奇 刘利民 黄高明 |
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| 作者单位： | 湖南师范大学第二附属医院（解放军第163医院）肿瘤科，湖南 长沙 410003 |
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| 摘 要： | 目的:探讨肝动脉化疗栓塞术（trashepatic arterial chem otherapy and embolization,TACE)联合体部伽玛刀治疗巨块型原发性肝癌的疗效及毒副反应。方法:对38例非手术治疗的巨块型肝癌患者行TACE联合体部伽玛刀治疗，伽玛刀治疗结束后4周行肝脏CT或MRI检查评价疗效，以后定期随访复查。结果:近期疗效:完全缓解（CR）0例，部分缓解(PR)23例，稳定(SD)12例，进展(PD)3例，近期总有效率(RR)92.1%。1、3、5年生存率分别为81.6%、10.5%、5.3%。主要毒副反应为消化道反应、骨髓抑制及放射性肝炎，患者均能耐受。结论:TACE联合体部伽玛刀治疗巨块型肝癌的效果好，毒副反应较轻。
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| 关 键 词： | 巨块型肝癌 TACE 体部伽玛刀 放射治疗 疗效 |
The clinical of observation of TACE combinied with body gamma knife radiotherapy for the treatment of huge hepatocellular carcinoma |
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| Cai Weiwei,Su Jiali,Yang Yu,Zhu Daoqi,Liu Limin,Huang Gaoming.The clinical of observation of TACE combinied with body gamma knife radiotherapy for the treatment of huge hepatocellular carcinoma[J].Journal of Modern Oncology,2018,0(8):1236-1239. |
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| Authors: | Cai Weiwei Su Jiali Yang Yu Zhu Daoqi Liu Limin Huang Gaoming |
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| Affiliation: | Department of Oncology,163 Hospital of PLA,Second Affiliated Hospital,Hunan Normal University，Hunan Changsha 410003，China. |
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| Abstract: | Objective:To evaluate the clinical efficacy and side reactions of TACE combined with body gamma knife radiotherapy for patients with huge hepatocellular carcinoma.Methods:38 cases of non-surgical treatment of huge hepatocellular carcinoma patients were treatment by TACE combined with body gamma knife radiotherapy.4 weeks after gamma knife treatment,hepatic CT or MRI examinations were performed to evaluate the efficacy.All patients were followed up and reexamined regularly.Results:Short-term effictive:complete remission in 0 cases,partial remission in 23 cases,stable disease in 12 cases,progress disease in 3 cases，and the short‐term effective rate was 92.1%.The 1,3 and 5 years survival rate was 81.6%,10.5%and 5.3% respectively.The main adverse events were digestive tract reaction,myelosuppression and radioactive hepatitis.All of the patients were tolerable.Conclusion:TACE combined with body gamma knife radiotherapy for the treatment of patients with huge hepatocellular carcinoma has good effect with mild side reactions. |
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| Keywords: | huge hepatocellular carcinoma TACE body gamma-knife radiotherapy efficacy |
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