| 加减八珍汤辅助治疗小儿神经母细胞瘤的效果观察 |
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| 引用本文： | 梁小辉,孟战备,郑红玲.加减八珍汤辅助治疗小儿神经母细胞瘤的效果观察[J].现代肿瘤医学,2019,0(3):489-492. |
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| 作者姓名： | 梁小辉 孟战备 郑红玲 |
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| 作者单位： | 洛阳市妇女儿童医疗保健中心儿科，河南 洛阳 471000 |
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| 摘 要： | 目的:观察加减八珍汤辅助治疗小儿神经母细胞瘤的临床疗效。 方法:将80例小儿神经母细胞瘤患者按照随机数字表法分为2组，每组各40例。实验组在基础治疗上给予加减八珍汤治疗，对照组在基础治疗上予以安慰剂，均连续治疗4周，同时观察治疗期间中医证候变化、治疗效果、生活质量、肿瘤进展、不良反应等情况。4周后，以生活质量评分表、中医症状量表进行问卷调查，统计药物干预前后各组患者评分并进行数据分析。结果:两组患儿治疗前各症状程度比较，差异无统计学意义；服加减八珍汤治疗后，实验组疗效评价较治疗前均改善（P<0.05），且实验组总体生活质量评分均优于对照组（P<0.05）。结论:加减八珍汤辅助治疗小儿神经母细胞瘤有显著效果，可提高患者生存质量，且疗效安全、可行。
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| 关 键 词： | 小儿神经母细胞瘤 加减八珍汤 肿瘤 传统中医药治疗 |
Clinical observation of modified bazhen decoction on pediatric neuroblastoma |
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| Liang Xiaohui,Meng Zhanbei,Zheng Hongling.Clinical observation of modified bazhen decoction on pediatric neuroblastoma[J].Journal of Modern Oncology,2019,0(3):489-492. |
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| Authors: | Liang Xiaohui Meng Zhanbei Zheng Hongling |
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| Affiliation: | Department of Paediatrics，Women and Children Health Care Center of Luoyang，Henan Luoyang 471000，China. |
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| Abstract: | Objective:To observed the clinical effect of adjuvant treatment of Bazhen decoction on pediatric neuroblastoma.Methods:Eighty children with neuroblastoma were divided into two groups according to the random number table:40 in each group.The experimental group was treated with addition and subtraction of Bazhen decoction on the basis of treatment，while the control group was given placebo on the basis of treatment for 4 weeks.Meanwhile，we observed the changes of TCM syndrome，treatment affect，quality of life，tumor progression，adverse reactions and so on.After 4 weeks，questionnaires were made with the quality of life scale and Chinese symptom checklist，and the scores of all the patients before and after drug intervention were statistically analyzed.Results:There was no significant difference in symptoms between the two groups before treatment.After treatment with Bazhen decoction，the curative effect of the experimental group was better than that before treatment(P<0.05)，and the overall quality of life score was better than the control group(P<0.05).Conclusion:The addition and subtraction Bazhen Decoction adjuvant treatment of children with neuroblastoma have a significant effect，which can improve the quality of life of patients，and the efficacy of safe and feasible. |
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| Keywords: | pediatric neuroblastoma modified bazhen decoction tumor traditional Chinese medicine treatment |
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