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广州市吸毒人群乙型肝炎病毒感染状况及感染模式调查
引用本文:李美霞,徐慧芳.广州市吸毒人群乙型肝炎病毒感染状况及感染模式调查[J].疾病监测,1999,14(10):368-372.
作者姓名:李美霞  徐慧芳
作者单位:1.广州市卫生防疫站 510080
摘    要:为了解广州市吸毒人群乙型肝炎病毒(HBV) 感染情况,用ELIASA法对1995 ~1998 年在广州市某戒毒所戒毒的1663 人毒瘾者进行HBV感染标志物检测。结果吸毒人群HBsAg 携带率为19.9 % ,HBV总感染率为86 .1 % 。静脉注射毒瘾者HBsAg 阳性率(22 .8% ) 明显高于口吸( 追龙) 毒瘾者(12 .3 % ) ,差异有统计学意义(P< 0 .01) ;男性毒瘾者HBsAg 携带率(21 .2 % ) 高于女性(14 .1 % ) ,二者差异有显著性。调查发现1432 例HBV感染的吸毒人群乙型肝炎病毒的感染模式有21 种,其中以HBsAb、HBcAb、HBsAb、HBcAb 、HBsAg、HBeAb、HBcAb 、HBsAg、HBeAg、HBcAb 及HBsAg、HBeAg 为多见,阳性构成分别为28 .56 % 、20.39 % 、16.41 % 、8 .59 % 、6.49% 、和6.20% 。应采取加强吸毒人群防病知识宣传,同时实施乙肝疫苗免疫的综合性防制措施,以控制该人群乙型肝炎的传播和流行。

关 键 词:乙型肝炎病毒    HBsAg携带率    感染模式

Study on HBV Infection and Infection Modes in Drug Users in Guangzhou
Li Meixia,et al.Study on HBV Infection and Infection Modes in Drug Users in Guangzhou[J].Disease Surveillance,1999,14(10):368-372.
Authors:Li Meixia  
Affiliation:1.Sanitation and Anti-epdemic Station of Guangzhou 510080
Abstract:The aim of this study was to describe the situation of hepatitis B virus(HBV)infection in drug users in Guangzhou. 1663 drug users who received treatment in a detoxification institute in Guangzhou during 1995 to 1998 were describe for HBV markers by ELIASA. The result showed that HBsAg carrying rate was 19.9% and higher in intravenous drug users (22.8%) than that in oral drug users (12.3%) also was higher in male drug users (21.2%) than in female drug users (14.4%), both had statistical significance. There were 21 infection modes in the 1432 HBV positive drug users, of which HBsAb·HBcAb,HBcAb,HBsAg·HBeAb·HBsAg·HBeAg·HBcAb and HBsAg were common.Their consititution rate were 28.56%,20.39%,16.41%,8.59%,6.49%,and 6.20% respectively.Combination strategies of health education and vaccination were recommended in order to control HBV transmission in drug users.
Keywords:HBV  HBsAg carrying rate  Infection modes
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