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肝硬化的磁共振扩散加权成像研究
引用本文:杨正汉,谢敬霞,章跃武,胡碧芳.肝硬化的磁共振扩散加权成像研究[J].中国医学影像技术,2002,18(9):907-909.
作者姓名:杨正汉  谢敬霞  章跃武  胡碧芳
作者单位:1. 卫生部北京医院,北京大学第五临床医学院放射科,北京,100730
2. 北京大学第三医院
3. 浙江省衢州市人民医院
4. 浙江省义乌市人民医院
摘    要:目的 探讨肝硬化水分子扩散的变化及其机制。方法 对 5 9例志愿者及 47例肝硬化病人进行扩散加权成像并测量肝脏ADC值。DWI序列A的b值分别为 3 0、3 0 0、110 0s/mm2 ;序列B分别为 1.6和 5 5s/mm2 。序列A分别用b1和b3 (ADC1)及b2 和b3 (ADC2 )计算ADC值 ,序列B用b1和b2 (ADC3 )计算。结果 ChildB、C级肝硬化平均ADC3 明显低于正常肝脏 ,平均ADC1低于正常肝脏 ,平均ADC2 与正常肝脏无差别。结论 肝硬化ADC值降低的主要原因可能为肝实质内血流灌注的减少而非纤维化限制了水分子的热运动。

关 键 词:肝硬化  扩散加权成像  磁共振成像
文章编号:1003-3289(2002)09-0907-03
收稿时间:2002/4/26 0:00:00
修稿时间:2002年4月26日

Study on Diffusion Weighted Imaging in Cirrhotic Liver
YANG Zheng-han,XIE Jing-xi,ZHANG Yue-wu and HU Bi-fang.Study on Diffusion Weighted Imaging in Cirrhotic Liver[J].Chinese Journal of Medical Imaging Technology,2002,18(9):907-909.
Authors:YANG Zheng-han  XIE Jing-xi  ZHANG Yue-wu and HU Bi-fang
Affiliation:Department of Radiology, Beijing Hospital, Beijing 100730, China
Abstract:Objective To investigate the change of ADC value in cirrhotic liver and its mechanism. Methods Diffusion weighted imaging (DWI) was performed in 59 volunteers and 47 patients with liver cirrhosis, and the ADC values of the liver were measured. Two sequences were used in this study. The b values were 30, 300 and 1100s/mm 2 in sequence A, while 1.6s/mm 2 and 55s/mm 2 in sequence B respectively. Results The mean ADC 3 in Child B and C cirrhosis was significantly lower than that in normal liver, the mean ADC 1 was lower than that in normal liver, however, the mean ADC 2 was approximate between the two groups. Conclusion The main cause of ADC value reduction in the cirrhotic liver may not be limitation of motion of water molecules by fibrosis, but decreased blood perfusion in the liver.
Keywords:Cirrhosis  Diffusion weighted imaging  Magnetic resonance imaging  
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