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实时剪切波弹性成像评价新生儿脑损伤的临床研究
引用本文:唐亚娟,赖为柽,曾飘逸,陈建辉,何韶铮,吕国荣.实时剪切波弹性成像评价新生儿脑损伤的临床研究[J].临床超声医学杂志,2020,22(1):61-63.
作者姓名:唐亚娟  赖为柽  曾飘逸  陈建辉  何韶铮  吕国荣
作者单位:362000 福建省泉州市,福建医科大学附属第二医院超声科;泉州医高专母婴健康服务应用技术协同创新中心
基金项目:福建省卫生计生科研人才培养项目资助计划省医学创新课题(2017-CXB-9)
摘    要:目的探讨实时剪切波弹性成像(SWE)量化评价新生儿脑损伤的临床应用价值。方法将行颅脑超声检查的134例新生儿分为早产儿组(38例,胎龄<37周)和足月儿组(96例,胎龄≥37周),根据新生儿缺血缺氧性脑病(HIE)诊断标准将96例足月儿分为足月正常组42例和足月HIE组54例,根据早产儿脑白质损伤超声诊断标准将38例早产儿分为无脑白质损伤组20例和脑白质损伤组18例。应用SWE测量新生儿顶叶、丘脑及小脑的杨氏模量值,比较早产儿组和足月儿组新生儿脑损伤不同部位杨氏模量值间的差异。结果足月正常组丘脑及小脑的杨氏模量值均大于足月HIE组(均P<0.05);无脑白质损伤组顶叶及小脑的杨氏模量值均大于脑白质损伤组(均P<0.05);结论 SWE可以定量评价新生儿大脑、丘脑和小脑硬度,为临床诊断脑损伤提供依据,具有较好的应用价值。

关 键 词:剪切波弹性成像  实时  缺血缺氧性脑病  脑白质损伤  新生儿

Clinical study of real-time shear wave elastography in evaluating neonatal brain injury
TANG Yajuan,LAI Weicheng,ZENG Piaoyi,CHEN Jianhui,HE Shaozheng,LV Guorong.Clinical study of real-time shear wave elastography in evaluating neonatal brain injury[J].Journal of Ultrasound in Clinical Medicine,2020,22(1):61-63.
Authors:TANG Yajuan  LAI Weicheng  ZENG Piaoyi  CHEN Jianhui  HE Shaozheng  LV Guorong
Affiliation:(Department of Ultrasound,the Second Affiliated Hospital of Fujian Medical University,Fujian 362000,China)
Abstract:ObjectiveTo explore the clinical application value of real-time shear wave elastography(SWE)in quantitatively evaluate the neonatal brain injury.MethodsA total of 134 neonates who underwent craniocerebral ultrasound were selected.There were 38 premature infants(less than 37 weeks)and 96 cases of full-term infants(more than 37 weeks).According to the diagnostic criteria of neonatal hypoxic-ischemic encephalopathy(HIE)in neonates,96 full-term infants were divided into full-term normal group(42 cases) and full-term HIE group(54 cases).According to the ultrasonic diagnostic criteria,38 premature infants were divided into non white matter damage group(20 cases)and white matter damage group(18 cases).SWE was performed on the parietal lobe,thalamus and cerebellum of the newborn,and the corresponding Young’s modulus value was measured to compare the difference of Young’s modulus value in different parts of the brain damage of the newborn.ResultsThe Young’s modulus of thalamus and cerebellum in full-term normal group were higher than those in full-term HIE group(both P<0.05).The Young’s modulus of parietal lobe and cerebellum in non while matter damage group were higher than those in white matter damage group(both P<0.05).ConclusionSWE can quantitatively evaluate the elastic of parietallobe,thalamus and cerebellum,and it can serve as a basis for the more accurate diagnosis of neonatal brain injury.
Keywords:Shear wave elastography  real-time  Hypoxic-ischemic encephalopathy  White matter damage  neonates
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