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Transferable, Plasmid-Mediated VanB-Type Glycopeptide Resistance in Enterococcus faecium
Authors:Louis B. Rice   Lenore L. Carias   Curtis L. Donskey     Susan D. Rudin
Affiliation:Infectious Diseases Section and Research Service, Cleveland Department of Veterans Affairs Medical Center,1. and the Department of Medicine, Case Western Reserve University School of Medicine,2. Cleveland, Ohio
Abstract:
An approximately 60-kb transferable, vanB-carrying plasmid has been identified in a clinical Enterococcus faecium strain. A similar plasmid has been observed in an unrelated E. faecium strain, suggesting that plasmid transfer of vanB operons occurs in nature and plays a role in the dissemination of VanB-type resistance among strains of E. faecium.
Keywords:
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