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Screening for ROS1 gene rearrangements in non‐small‐cell lung cancers using immunohistochemistry with FISH confirmation is an effective method to identify this rare target
Authors:Christina I Selinger  Bob T Li  Nick Pavlakis  Matthew Links  Anthony J Gill  Adrian Lee  Stephen Clarke  Thang N Tran  Trina Lum  Po Y Yip  Lisa Horvath  Bing Yu  Maija R J Kohonen‐Corish  Wendy A Cooper
Affiliation:1. Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia;2. Department of Medical Oncology, Royal North Shore Hospital, St Leonards, NSW, Australia;3. Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, USA;4. Sydney Medical School, University of Sydney, Camperdown, NSW, Australia;5. Department of Medical Oncology, St George Hospital, Kogarah, NSW, Australia;6. Cancer Diagnosis and Pathology Group, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards, NSW, Australia;7. The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia;8. School of Medicine, University of Western Sydney, Sydney, NSW, Australia;9. Chris O'Brien Lifehouse, Camperdown, NSW, Australia;10. Macarthur Cancer Therapy Centre, Campbelltown Hospital, Camperdown, NSW, Australia;11. Medical Oncology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia;12. Department of Medical Genomics, Royal Prince Alfred Hospital, Camperdown, NSW, Australia;13. St Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW, Australia;14. School of Medicine, University of Western Sydney, Sydney, NSW, AustraliaEqual last authors.
Abstract:
Keywords:c‐ros oncogene 1 (ROS1)  fluorescence in‐situ hybridization (FISH)  immunohistochemistry (IHC)  non‐small‐cell lung cancer (NSCLC)
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