High susceptibility of human dendritic cells to invasion by the intracellular pathogens Brucella suis, B. abortus, and B. melitensis |
| |
| Authors: | Billard Elisabeth Cazevieille Chantal Dornand Jacques Gross Antoine |
| |
| Affiliation: | INSERM U431, Université Montpellier II, cc100, Place E. Bataillon, 34095 Montpellier, France. |
| |
| Abstract: | Bacteria from the Brucella genus are able to survive and proliferate within macrophages. Because they are phylogenetically closely related to macrophages, myeloid dendritic cells (DCs) constitute potential targets for Brucella bacteria. Here we report that DCs display a great susceptibility to Brucella infection. Therefore, DCs might serve as a reservoir and be important for the development of Brucella bacteria within their host. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
