| 栅栏状中性粒细胞肉芽肿性皮炎合并强直性脊柱炎一例 |
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| 引用本文： | 甘璐,陈浩,孙建方. 栅栏状中性粒细胞肉芽肿性皮炎合并强直性脊柱炎一例[J]. 中国麻风皮肤病杂志, 2018, 34(9): 552-554 |
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| 作者姓名： | 甘璐 陈浩 孙建方 |
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| 作者单位： | 中国医学科学院北京协和医学院皮肤病研究所病理科,南京,210042 |
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| 摘 要： | 患者,男,55岁。四肢暗红色斑块、脱屑5年。既往有强直性脊柱炎病史。皮损组织病理学检查示真皮内上皮细胞肉芽肿改变,部分区域上皮细胞呈栅栏状排列,局部伴有中性粒细胞、淋巴细胞浸润。实验室检查抗核抗体、SSA、SSB、抗双链DNA等为阴性,HLA-B27为阳性。诊断：栅栏状中性粒细胞肉芽肿性皮炎合并强直性脊柱炎。
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| 关 键 词： | 栅栏状中性粒细胞肉芽肿性皮炎 强直性脊柱炎 |
Palisade neutrophilic and granulomatous dermatitis complicated with ankylosing spondylitis: a case report |
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| GAN Lu,CHEN Hao,SUN Jian-fang. Palisade neutrophilic and granulomatous dermatitis complicated with ankylosing spondylitis: a case report[J]. China Journal of Leprosy and Skin Diseases, 2018, 34(9): 552-554 |
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| Authors: | GAN Lu CHEN Hao SUN Jian-fang |
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| Affiliation: | Department of Pathology, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042 , China |
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| Abstract: | A 55-year-old male presented with erythematous plaques and scales on the extensor surface of extremities for 5 years. He has a history of ankylosing spondylitis (AS) for 10 years.. The biopsy showed granulomatous?nodules in the dermis, and some histiocytes, lymphocytes, neutrophils in a pattern of palisading arrangement. Antinuclear antibody, anti-SS-B, anti-SS-A and anti–double-stranded DNA were negative. HLA-B27 was positive. The diagnosis of palisaded neutrophilic granulomatous dermatitis companied with ankylosing spondylitis was made. |
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| Keywords: | palisaded neutrophilic granulomatous dermatitis ankylosing spondylitis |
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