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| 药物副反应主观体验对精神分裂症服药依从性的预测作用 | |
| 引用本文： | 陈春棉,林崇光,姜德国. 药物副反应主观体验对精神分裂症服药依从性的预测作用[J]. 中华全科医学, 2021, 19(2): 274-276,279. DOI: 10.16766/j.cnki.issn.1674-4152.001786 |
| 作者姓名： | 陈春棉 林崇光 姜德国 |
| 作者单位： | 温州市第七人民医院护理部;温州市第七人民医院心身科;温州市第七人民医院急重症精神科 |
| 基金项目： | 浙江省医药卫生科技计划项目(2018KY764);温州市科学技术局项目(Y20180557)。 |
| 摘 要： | 目的 检验抗精神病药物副反应主观体验对精神分裂症患者服药依从性的预测价值.方法 选择2019年3-6月温州市第七人民医院收治的123例精神分裂症患者,在出院时完成格拉斯哥精神病药物副反应评定量表(Glasgow antipsychotics side-effect scale,GASS)评分.在患者出院后的4～5周,完... |
| 关 键 词： | 精神分裂症 服药依从性 格拉斯哥精神病药物副反应评定量表 |
| 收稿时间： | 2020-11-05 |
Predictive effect of subjective experience of antipsychotic side effects on medication compliance in schizophrenia |
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| CHEN Chun-mian,LIN Chong-guang,JIANG De-guo. Predictive effect of subjective experience of antipsychotic side effects on medication compliance in schizophrenia[J]. Applied Journal Of General Practice, 2021, 19(2): 274-276,279. DOI: 10.16766/j.cnki.issn.1674-4152.001786 | |
| Authors: | CHEN Chun-mian LIN Chong-guang JIANG De-guo |
| Affiliation: | Nursing Department, The Seventh Hospital of Wenzhou, Wenzhou, Zhejiang 325005, China |
| Abstract: | Objective To examine the predictive value of subjective experience of antipsychotic side effects on medication compliance in patients with schizophrenia. Methods One hundred and twenty-three patients with schizophrenia completed the Glasgow Antipsychotics Side-effect Scale(GASS) at discharge, and medication compliance follow-up was completed 4-5 weeks after discharge. In the receiver operating curve, the total GASS score was used as the independent variable. The area under the curve was calculated, and the sensitivity and specificity were predicted. Results Fifty-two patients(42.3%) were defined as medication non-compliance. The total score of GASS(OR=1.105, 95% CI=1.041-1.173) and the score of extrapyramidal side effect of GASS(OR=7.965, 95% CI=2.371-26.754) were significantly associated with medication non-compliance(all P<0.01). Receiver operating characteristic curve analysis indicated that the suitable cut-off points on total score of GASS for identifying medication non-compliance was ≥20(sensitivity and specificity were 92.3% and 66.2%, respectively). Conclusion The subjective experience of antipsychotic side effects can be used to predict medication non-compliance in patients with schizophrenia. |
| Keywords: | Schizophrenia Medication compliance Glasgow antipsychotics side-effect scale |
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