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| 大疱性类天疱疮合并获得性血友病一例 | |
| 引用本文： | 车炫霖,粟娟,陈明亮. 大疱性类天疱疮合并获得性血友病一例[J]. 中国麻风皮肤病杂志, 2022, 38(2): 110-111. DOI: 10.12144/zgmfskin202202110 |
| 作者姓名： | 车炫霖 粟娟 陈明亮 |
| 作者单位： | 1中南大学湘雅医院皮肤科，湖南长沙，410008;2皮肤肿瘤与银屑病湖南省重点实验室，湖南长沙，410008;3皮肤健康与疾病湖南省工程研究中心，湖南长沙，410008;4国家老年疾病临床医学研究中心，湖南长沙，410008 |
| 摘 要： | 获得性血友病A(acquired hemophilia A, AHA)死亡率为15%～42%,约50%左右的AHA为特发性,而另外50%与一些基础疾病有关,如系统性红斑狼疮、肿瘤、药物过敏、皮肤病(如银屑病,大疱性类天疱疮)等。本文报道一例大疱性类天疱疮合并获得性血友病,采用泼尼松、人凝血酶原复合物联合环孢素治疗后取得了显著疗效。 |
| 关 键 词： | 大疱性类天疱疮 获得性血友病 Ⅷ因子抑制剂 |
Acquired hemophilia associated with bullous pemphigus: a case report |
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| CHE Xuanlin,SU Juan,CHEN Mingliang. Acquired hemophilia associated with bullous pemphigus: a case report[J]. China Journal of Leprosy and Skin Diseases, 2022, 38(2): 110-111. DOI: 10.12144/zgmfskin202202110 | |
| Authors: | CHE Xuanlin SU Juan CHEN Mingliang |
| Affiliation: | 1 Department of Dermatology, Xiangya Hospital, Central South University, Changsha 410008, China; 2 Hunan Key Laboratory of Skin Cancer and Psoriasis, Central South University, Changsha 410008, China; 3 Hunan Engineering Research Center of Skin Health and Disease, Central South University, Changsha 410008, China; 4 National Clinical Research Center for Geriatric Disorders (Xiangya Hospital), Changsha 410008, China |
| Abstract: | The mortality rate of acquired hemophilia A (AHA) is 15%-42%, about 50% of AHA is idiopathic, and the other 50% is related to some underlying diseases, such as systemic lupus erythematosus, tumor, drug allergy, skin diseases (such as psoriasis, bullous pemphigoid) and so on. Herein, we report a patient with bullous pemphigoid complicated with AHA, who achieved significant efficacy after comprehensive treatment of oral prednisone and human prothrombin complex, cyclosporine. |
| Keywords: | bullous pemphigoid acquired hemophilia factor Ⅷ inhibitor |
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