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个体化饮食指导对肝癌患者肝动脉灌注化疗栓塞术后营养状况和生活质量的影响
引用本文:陶敏洁,雷宇,金俊,汤桂芳,王莉.个体化饮食指导对肝癌患者肝动脉灌注化疗栓塞术后营养状况和生活质量的影响[J].中华全科医学,2022,20(3):507-510.
作者姓名:陶敏洁  雷宇  金俊  汤桂芳  王莉
作者单位:1.浙江大学医学院附属杭州市第一人民医院肝胆外科,浙江 杭州 310006
基金项目:浙江省医药卫生科技计划项目2020PY015
摘    要:目的 探讨个体化饮食指导对肝癌患者肝动脉灌注化疗栓塞术(TACE)术后营养状况及生活质量的影响.方法 选取2019年3月-2020年3月在浙江大学医学院附属杭州市第一人民医院行TACE术后患者120例为研究对象,根据入院先后顺序分为观察组(62例)和对照组(58例).对照组术后给予常规饮食干预,观察组术后在常规饮食干预...

关 键 词:肝癌  肝动脉灌注化疗栓塞术  个体化营养指导  营养状况  生活质量
收稿时间:2020-11-25

Effect of individualised dietary guidance on nutritional status and quality of life of liver cancer patients after TACE
Affiliation:Department of Hepatobiliary Surgery, Hangzhou First People's Hospital, Hangzhou, Zhejiang 310006, China
Abstract:  Objective  To investigate the effect of individualised diet guidance on nutritional status and quality of life of liver cancer patients after transcatheter arterial chemoembolisation (TACE).  Methods  Total 120 patients who underwent TACE in Hangzhou first people's Hospital Affiliated to the Medical College of Zhejiang University from March 2019 to March 2020 were selected as the research objects. They were divided into observation group (62 cases) and control group (58 cases) according to the order of admission. The control group was given routine dietary intervention after surgery, and the observation group was given individualised dietary guidance on the basis of routine nutrition after surgery. The preoperative and postoperative nutritional status of the two groups was compared, and their preoperative and postoperative nutritional risk was evaluated.  Results  On the 7th day after surgery, the ALB level in both groups was higher than that before surgery (all P < 0.05). Three months after operation, the ALB level in both groups was significantly higher than that before operation and 7 days after operation (all P < 0.05), and the ALB level in the observation group was significantly higher than that in the control group (P < 0.05). At 7 days after surgery, PALB indexes in both groups were decreased compared with those before surgery (all P < 0.05), but the observation group had significantly higher indexes than the control group (P < 0.05). Three months after surgery, the PALB level in both groups was significantly higher than that before surgery and 7 days after surgery (all P < 0.05). The PALB level in the observation group was significantly higher than that in the control group (P < 0.001). Three months after operation, the proportion of lean weight in the observation group was significantly lower than that in the control group8(12.91%) vs. 16(27.59%), P < 0.05]. Three months after operation, the incidence of nutritional risk in the observation group was significantly lower than that in the control group16(25.81%) vs. 26(44.83%), χ2=4.766, P=0.029]. Three months after operation, the scores of EORTC QLQ-C30 in the observation group were significantly higher than those in the control group (all P < 0.001).  Conclusion  Individualised dietary guidance can effectively improve the nutritional status of liver cancer patients after TACE, reduce the incidence of malnutrition risk and improve the quality of life of patients, which is worthy of clinical promotion and use. 
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