| 2型糖尿病干眼患者与正常干眼患者睑板腺及泪膜脂质层特征比较 |
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| 引用本文： | 李科军,赵智华,樊芳,李晓丹,贾志旸. 2型糖尿病干眼患者与正常干眼患者睑板腺及泪膜脂质层特征比较[J]. 眼科新进展, 2022, 0(3): 222-225. DOI: 10.13389/j.cnki.rao.2022.0045 |
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| 作者姓名： | 李科军 赵智华 樊芳 李晓丹 贾志旸 |
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| 作者单位： | 050051 河北省石家庄市，河北省人民医院眼科（李科军，赵智华，樊芳，贾志旸）；050000 河北省石家庄市，石家庄市第一医院眼科（李晓丹） |
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| 摘 要： | 目的 观察不同病程的2型糖尿病干眼患者与正常干眼患者睑板腺结构及泪膜脂质层厚度变化,探讨糖尿病患者干眼的发病特点,进一步指导临床治疗.方法 经泪膜破裂时间(BUT)测定和眼表疾病指数(OSDI)量表确诊的糖尿病干眼患者130例(130眼,糖尿病组)及正常干眼患者46例(46眼,正常对照组),其中糖尿病组以病程为界再分为...
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| 关 键 词： | 2型糖尿病 泪膜脂质层厚度 睑板腺功能 干眼 |
Comparison of meibomian glands and tear film lipid layers between patients with type 2 diabetes combined with dry eye and patients with dry eye |
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| LI Kejun,ZHAO Zhihua,FAN Fang,LI Xiaodan,JIA Zhiyang. Comparison of meibomian glands and tear film lipid layers between patients with type 2 diabetes combined with dry eye and patients with dry eye[J]. Recent Advances in Ophthalmology, 2022, 0(3): 222-225. DOI: 10.13389/j.cnki.rao.2022.0045 |
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| Authors: | LI Kejun ZHAO Zhihua FAN Fang LI Xiaodan JIA Zhiyang |
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| Affiliation: | Hebei Provincial People’s Hospital,Shijiazhuang 050051,Hebei Province,China |
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| Abstract: | Objective To observe the changes in the meibomian gland structure and tear film lipid layer thickness (LLT) between patients with type 2 diabetes combined with dry eye and patients with dry eye, and explore the clinical characteristics of dry eye in diabetic patients to guide clinical treatment.Methods A total of 130 patients with diabetes mellitus (DM) and dry eye diagnosed by break-up time (BUT) and ocular surface disease index (OSDI) were selected into the DM group, and 46 normal dry eye patients were selected into the normal control (NC) group. Patients in the DM group were subdivided into group A (course of the disease<10 years) and group B (course of the disease>10 years). All patients’ LLT, percentage of meibomian glands (MGP), meibomian glands yielding liquid secretion (MGYLS), and meibomian gland yielding secretion score (MGYSS) were evaluated and compared using the LipiView? Ocular Surface Interferometer. Schirmer’s I test (SIt) was performed on all patients.Results There were significant differences in LLT, MGP, MGYLS, MGYSS, BUT, and SIt between the DM group and the NC group (all P<0.05). The MGP, MGYLS, and MGYSS in group B were significantly lower than those in the NC group and group A (all P<0.05). The OSDI showed no significant difference between the DM group and the NC group (P>0.05). Conclusion For type 2 DM patients with dry eye, the longer the course of the disease is, the higher the MGP is, the smaller the MGYLS is, and the lower the MGYSS is. That’s why DM patients have a higher prevalence of dry eye. |
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| Keywords: | type 2 diabetes lipid layer thickness meibomian gland function dry eye |
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