| 脂溶性和水溶性碘对比剂在子宫输卵管造影中的比较研究 |
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| 引用本文： | 牛倩 段丽丽. 脂溶性和水溶性碘对比剂在子宫输卵管造影中的比较研究[J]. 国际医药卫生导报, 2022, 28(24): 3548. DOI: 10.3760/cma.j.issn.1007-1245.2022.24.031 |
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| 作者姓名： | 牛倩 段丽丽 |
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| 作者单位： | 中山大学附属第六医院生殖医学中心,广州 510610 |
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| 摘 要： | 目的 比较脂溶性碘对比剂（碘油）和水溶性碘对比剂（碘水）对不孕症妇女子宫输卵管造影（HSG）数字化X线摄影（DR）图像质量和术后妊娠率的影响。方法 研究对象均来源于中山大学附属第六医院生殖医学中心2014年6月至2018年6月在不孕症门诊就诊的不孕症患者。共625例进行了HSG检查,并具有完整的影像、临床资料,其中碘油组124例、碘水组501例,HSG后随访6～12个月。碘油组中位年龄29.0岁,中位不孕时间22.5个月;碘水组中位年龄30.0岁,中位不孕时间21.5个月。比较两组HSG的显影质量优良率和随访妊娠率。采用χ2检验。结果 2种对比剂HSG均获得了较好的图像。碘油组HSG影像优良率95.97%（119/124）,与碘水组［95.41%（478/501）］比较,差异无统计学意义（χ2=0.072,P=0.788）。碘油组术后妊娠率为38.71%（48/124）,与碘水组［37.92%（190/501）］比较,差异无统计学意义（χ2=0.026,P=0.872）。碘油对比剂使宫腔轮廓更加清晰,碘水对比剂显示更多的输卵管细节,二者均未引起严重并发症。结论 常规HSG使用碘油和碘水对比剂,对诊断影像和术后妊娠率无明显影响。
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| 关 键 词： | 子宫输卵管造影 碘对比剂 妊娠率 |
| 收稿时间： | 2022-09-23 |
Lipid-soluble and water-soluble iodine contrast agents forhysterosalpingography: a comparative study of clinical application |
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| Niu Qian,Duan Lili. Lipid-soluble and water-soluble iodine contrast agents forhysterosalpingography: a comparative study of clinical application[J]. International Medicine & Health Guidance News, 2022, 28(24): 3548. DOI: 10.3760/cma.j.issn.1007-1245.2022.24.031 |
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| Authors: | Niu Qian Duan Lili |
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| Affiliation: | Reproductive Medicine Center, The Sixth Affiliated Hospital of SunYat-sen University, Guangzhou 510610, China |
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| Abstract: | Objective To compare the effects of lipid-soluble andwater-soluble iodine contrast agents (iodine oil and iodine water) on the imagequality of hysterosalpingography (HSG) digital radiology (DR) and postoperativepregnancy rate in infertile women. Methods The subjects were all infertility patients who visited theinfertility clinic in the Reproductive Medicine Center of The Sixth AffiliatedHospital of Sun Yat-Sen University from June 2014 to June 2018. A total of 625patients underwent HSG examination with complete imaging and clinical data,including 124 patients in the iodine oil group and 501 patients in the iodinewater group, and the patients were followed up for 6-12 months after HSG. Themedian age of the iodine oil group was 29.0 years old and the median infertilitytime was 22.5 months; the median age of the iodine water group was 30.0 yearsold and the median infertility time was 21.5 months. The excellent and goodrate of HSG image quality and follow-up pregnancy rate were compared betweenthe two groups. Chi-square test was used. Results Two kinds of agents for HSG had obtained the good images. Theexcellent and good rate of HSG image quality in the iodine oil group was 95.97%(119/124), and there was no statistically significant difference compared withthat in the iodine water group [95.41% (478/501)] (χ2=0.072, P=0.788).The postoperative pregnancy rate of the iodine oil group was 38.71% (48/124),and there was no statistically significant difference compared with that in theiodine water group [37.92% (190/501)] (χ2=0.026, P=0.872). The iodine oil contrastagent made the uterine cavity more defined, and the iodine water contrast agentshowed more details of the fallopian tube. No serious complications occurred ineither case. Conclusion Lipid-soluble and water-soluble iodine contrast agents for HSG haveno significant effects on diagnostic images and postoperative pregnancy rate. |
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| Keywords: | Hysterosalpingography Iodine contrast agent Pregnancy rate |
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