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青少年分化型甲状腺癌60例临床分析
引用本文:安玉胜,万福强. 青少年分化型甲状腺癌60例临床分析[J]. 现代肿瘤医学, 2015, 0(11): 1522-1524. DOI: 10.3969/j.issn.1672-4992.2015.11.13
作者姓名:安玉胜  万福强
作者单位:临沂市肿瘤医院头颈外科,山东 临沂 276001
摘    要:目的:讨论青少年分化型甲状腺癌的临床表现、诊断、最佳治疗方法及预后。方法:回顾性分析1995-2010年间收治的20岁以下青少年分化型甲状腺癌60例,均为散发病例。结果:全组均行手术辅以内分泌治疗。60例青少年甲状腺癌中乳头状腺癌51例,滤泡状癌9例。伴颈淋巴结转移者17例,其中双侧甲状腺癌并双颈淋巴结转移2例,占3.3%。手术方式包括甲状腺患侧腺叶加峡部切除45例(其中行患侧功能性颈清扫8例);患侧腺叶加峡部切除及对侧大部切除13例(其中行单侧颈清扫5例,双侧颈清扫2例);甲状腺全切术加双侧颈清扫术2例。术后均予甲状腺素内分泌抑制治疗。随访时间2-17年,其中25例获得10年以上随访。5年及10年生存率均为100%。结论:青少年分化型甲状腺癌多为乳头状癌,预后较好,彩超为首选诊断检查,细针穿刺细胞学确诊率高,治疗关键在于首次手术方式的合理选择。

关 键 词:青少年  分化型甲状腺癌  诊断  治疗

Clinical analysis of 60 cases with differentiaed thyroid carcinoma of adolescents
An Yusheng,Wan Fuqiang. Clinical analysis of 60 cases with differentiaed thyroid carcinoma of adolescents[J]. Journal of Modern Oncology, 2015, 0(11): 1522-1524. DOI: 10.3969/j.issn.1672-4992.2015.11.13
Authors:An Yusheng  Wan Fuqiang
Affiliation:Linyi City Tumor Hospital,Shandong Linyi 276001,China.
Abstract:Objective:To study the clinical characteristics,diagnosis,treatment and prognosis of adolescent thyroid carcinoma.Methods:The records of 60 cases of adolescent thyroid carcinoma under 20 years old between 1995 and 2010 were reviewed.All the cases were sporadic.Results:All patients underwent surgical treatment and hormone suppressive therapy.The pathological test revealed papillary carcinoma 51 cases,follicular carcinoma 9 cases.Cervical lymphonode metastasis was found in 17 cases,2 cases of them with bilateral cervical lymph node metastasis,were 3.3% in all the cases.Treatment consisted of lobectomy in 45 cases (8 cases received neck dissection),subtotal thyroidectomy in 13 cases (unilateral dissection in 5 and bilateral dissection in 2 cases),total thyroidectomy and bilateral dissection in 2 cases.All the cases received postoperative thyroid hormone suppressive therapy.The follow-up period was 2 to 17 years (with 25 cases over 10 years).The 5- and 10-year survival rates were 100%.Conclusion:Differentiaed thyroid carcinoma of adolescents has a good prognosis and color ultrasound is the primary examination method,fine needle aspiration is available for diagnosis.The first reasonable operational manner is the most important.
Keywords:adolescent  differentiaed thyroid carcinoma  diagnosis  treatment
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