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Update on therapeutic interventions for the management of achalasia
Authors:Nishmi Gunasingam  Adam Perczuk  Michael Talbot  Arthur Kaffes  Payal Saxena
Affiliation:1. Department of Gastroenterology and Hepatology, St Vincent's Hospital, Australia;2. Department of Gastroenterology and Hepatology, Prince of Wales Hospital, New South Wales, Australia;3. Department of Gastroenterology and Hepatology, St George Hospital, Sydney, Australia;4. Department of Gastroenterology and Hepatology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
Abstract:Achalasia is a primary esophageal motility disorder. It is the absence of peristalsis in the esophageal body and inability of the lower esophageal sphincter to relax, which characterizes this rare condition. Its features typically include dysphagia, regurgitation, chest pain, and weight loss. The ultimate goal in treating achalasia is to relieve the patient's symptoms, improve esophageal emptying, and prevent further dilatation of the esophagus. Current treatment modalities targeted at achalasia include pharmacological therapy, endoscopic therapy, and surgery. This review focuses on the current therapeutic options and explores the role of peroral endoscopic myotomy in the management armamentarium.
Keywords:achalasia  laparoscopic Heller myotomy  peroral endoscopic myotomy  POEM
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