| 基于渐进性抗阻训练的健康管理对绝经后骨质疏松女性跌倒风险的影响 |
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| 引用本文： | 俞小红,王红亚,傅华君.基于渐进性抗阻训练的健康管理对绝经后骨质疏松女性跌倒风险的影响[J].中华全科医学,2020,18(8):1337-1340. |
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| 作者姓名： | 俞小红 王红亚 傅华君 |
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| 作者单位： | 浙江中医药大学附属江南医院骨科, 浙江 杭州 311200 |
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| 基金项目： | 浙江省中医药科技计划项目(2020ZA095) |
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| 摘 要： | 目的 探讨基于渐进性抗阻训练的健康管理联合骨化三醇对绝经后骨质疏松女性Ⅰ型前胶原肽(CTX)、骨特异性碱性磷酸酶(BAP)及跌倒风险的影响。 方法 将2018年3月—2019年5月在浙江中医药大学附属江南医院接受治疗的96例绝经后骨质疏松患者纳入研究。根据数字随机表法分为观察组和对照组,观察组(48例)采取基于渐进性抗阻训练的健康管理联合骨化三醇干预,对照组(48例)采取骨化三醇干预。观察2组患者干预前后BAP、CTX的变化及跌倒风险评分,同时统计2组干预前后髋部骨密度、股骨粗隆骨密度变化情况。 结果 2组干预前后BAP、CTX水平比较差异无统计学意义(均P>0.05)。干预后观察组腰椎骨密度较干预前明显增加(P<0.05),但对照组腰椎骨密度较干预前无明显增加(P>0.05),且观察组干预后腰椎骨密度优于对照组(P<0.05),干预前后2组髋部骨密度、股骨粗隆骨密度比较差异无统计学意义(均P>0.05)。干预6个月后观察组跌倒指数显著优于对照组(P<0.05)。BAP、CTX与跌倒指数评分呈正相关(均P<0.05)。 结论 基于渐进性抗阻训练的健康管理联合骨化三醇对绝经后骨质疏松女性CTX、BAP及跌倒风险有良好的改善作用,并且较常规用药可增强对跌倒风险的预防。
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| 关 键 词： | 健康管理 渐进性抗阻训练 骨化三醇 骨质疏松 |
| 收稿时间： | 2019-12-30 |
Effect of health management combined with calcitriol based on progressive resistance training on CTX,BAP and Fall Risk in postmenopausal osteoporosis women |
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| Affiliation: | Department of Orthopedics,Jiangnan Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine,Hangzhou,Zhejiang 311200,China |
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| Abstract: | Objective To explore the effect of health management combined with calcitriol based on progressive resistance training on CTX(type I procollagen peptide), BAP(bone specific alkaline phosphatase) and fall risk in postmenopausal osteoporosis women. Methods Total 96 postmenopausal osteoporosis patients treated in our hospital from March 2018 to May 2019 were included in the study. They were divided into two groups according to the digital random table method. The observation group(48 cases) took health management based on progressive resistance training combined with calcitriol intervention. The control group(48 cases) received calcitriol intervention. The changes of BAP and CTX and the fall risk score before and after the intervention in the two groups were observed. Meanwhile, the changes of hip BMD and femoral trochanter BMD before and after the intervention in the two groups were counted. Results There was no significant difference in BAP and CTX levels between the two groups before and after intervention(all P>0.05). After the intervention, the lumbar bone density of the observation group was significantly increased(P<0.05), but the lumbar bone density of the control group was not significantly increased(P>0.05), and the lumbar bone density of the observation group after the intervention was better than that of the control group(P<0.05). There was no significant difference in hip bone density and femoral trochanter bone density between the two groups before and after the intervention(all P>0.05). After 6 months of intervention, the fall index in the observation group was significantly better than that in the control group(P<0.05). BAP, CTX were significantly positively correlated with fall index score(all P<0.05). Conclusion Health management based on progressive resistance training combined with calcitriol has a good improvement effect on CTX, BAP and fall risk of postmenopausal osteoporosis women, and can enhance the prevention of fall risk compared with conventional drugs. It has high clinical application value and is worthy of clinical promotion and wide application. |
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