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乳腺癌术后患者行VAP和PICC对相关并发症和生活质量的影响研究
引用本文:杨贵丽,曾会会,韩正全,毛燕,薛丹丹.乳腺癌术后患者行VAP和PICC对相关并发症和生活质量的影响研究[J].中华全科医学,2020,18(9):1595-1598.
作者姓名:杨贵丽  曾会会  韩正全  毛燕  薛丹丹
作者单位:蚌埠医学院第一附属医院肿瘤内科, 安徽 蚌埠 233004
基金项目:安徽省教育厅科研项目基金(KJ2018A0990)
摘    要:目的 对乳腺癌术后患者行植入式静脉输液港(venous-access ports,VAP)及经外周静脉置入中心静脉导管(peripheral inserted central catheter,PICC)的并发症情况和生活质量进行研究分析,提供临床依据。 方法 将蚌埠医学院第一附属医院2013年1月—2018年12月乳腺癌术后行辅助化疗的患者120例,根据输液工具的选择不同分为2组,58例行VAP为试验组,62例行PICC为对照组,比较2组置管后静脉血栓、导管感染、堵管和输注不畅发生情况和患者生活质量。 结果 试验组未发生静脉血栓、感染和输注不畅,发生堵管1例(1.7%),对照组发生静脉血栓3例(4.8%),感染4例(6.4%),堵管5例(8.1%),输液不畅2例(3.2%)。试验组并发症总发生1例(1.7%),对照组并发症总发生14例(22.6%),2组比较差异有统计学意义(χ2=11.918,P=0.001);VAP组患者生理领域、心理领域、社会关系领域、环境领域评分均优于PICC组,差异有统计学意义(均P<0.01)。 结论 乳腺癌术后患者行VAP,其静脉血栓、导管感染、堵管和输注不畅的发生率均低于PICC,并且可以提高患者生活质量。 

关 键 词:乳腺癌术后    植入式静脉输液港    经外周静脉置入中心静脉导管    并发症    生活质量
收稿时间:2019-10-10

Analyzing the complications and quality of life of patients receiving VAP and PICC after breast cancer surgery
Affiliation:Department of Oncology,the First Hospital of Bengbu Medical College,Bengbu,Anhui 233004,China
Abstract:Objective To analyze the complications and quality of life of patients receiving VAP and PICC after breast cancer surgery, and to provide clinical evidence. Methods A total of 120 patients who received adjuvant chemotherapy after breast cancer surgery in the First Hospital of Bengbu Medical College from January 2013 to December 2018 were divided into the experimental group(58 cases) and the control group(62 cases) by different of infusion tools. The incidence of complications such as venous thrombosis, catheter infection and catheter blockage after catheterization and the quality of life of the patients in the two groups were compared. Results There was no venous thrombosis, infection or infusion obstruction in the experimental group, with 1 case(1.7%) of venous thrombosis, 3 cases(4.8%) of venous thrombosis in the control group, 4 cases(6.4%) of venous thrombosis, 5 cases(8.1%) of infection, and 2 cases(3.2%) of infusion obstruction. Complications occurred in 1 case(1.7%) in the test group and 14 cases(22.6%) in the control group, χ2=11.918, P=0.001, the difference was statistically significant. The scores of patients in the VAP group in the physiological field, psychological field, social relation field and environmental field were all better than those in the PICC group(P<0.01), with statistically significant differences. Conclusion Compared with PICC, the incidence of VAP in patients with breast cancer is lower than that of PICC in terms of venous thrombosis, catheter infection and tube plugging, and it also improves the quality of life of patients, which is worthy of clinical promotion and application. 
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