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Human plasma-derived immunoglobulin G fractionated by an aqueous two-phase system,caprylic acid precipitation,and membrane chromatography has a high purity level and is free of detectable in vitro thrombogenic activity |
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| Authors: | M. Vargas Á. Segura Y.-W. Wu M. Herrera M.-L. Chou M. Villalta G. León T. Burnouf |
| Affiliation: | 1. Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica;2. Graduate Institute of Biomedical Materials and Tissue Engineering, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan;3. Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan;4. Graduate Institute of Biomedical Materials and Tissue Engineering, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan Correspondence: Thierry Burnouf, Graduate Institute of Biomedical Materials and Tissue Engineering, Taipei Medical University, 250 Wu-Shing Street, Taipei 110, Taiwan E-mail: tburnou@attglobal.net |
| Abstract: | |
| Keywords: | aqueous two-phase system chromatography immunoglobulin plasma fractionation thrombogenicity |