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Erythromycin and clindamycin resistance and telithromycin susceptibility in Streptococcus agalactiae
Authors:Betriu C  Culebras E  Gómez M  Rodríguez-Avial I  Sánchez B A  Agreda M C  Picazo J J
Affiliation:Department of Clinical Microbiology, Hospital Clínico San Carlos, 28040 Madrid, Spain. cbetriu@efd.net
Abstract:
The rates of resistance to erythromycin and clindamycin among Streptococcus agalactiae strains isolated in our hospital increased from 4.2 and 0.8% in 1993 to 17.4 and 12.1%, respectively, in 2001. Erythromycin resistance was mainly due to the presence of an Erm(B) methylase, while the M phenotype was detected in 3.8% of the strains. Telithromycin was very active against erythromycin-resistant strains, irrespective of their mechanisms of macrolide resistance.
Keywords:
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