| 不同分化程度子宫内膜癌表观扩散系数与DCE-MRI定量参数的关系 |
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| 引用本文： | 张明,孟迎春,周扬. 不同分化程度子宫内膜癌表观扩散系数与DCE-MRI定量参数的关系[J]. 现代肿瘤医学, 2021, 0(7): 1229-1233. DOI: DOI:10.3969/j.issn.1672-4992.2021.07.027 |
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| 作者姓名： | 张明 孟迎春 周扬 |
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| 作者单位： | 荆州市中心医院放射科,湖北 荆州 434020 |
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| 摘 要： | 目的:探究不同分化程度的子宫内膜癌表观扩散系数(apparent diffusion coefficient,ADC)与磁共振动态增强扫描成像(dynamic contrast enhanced MRI,DCE-MRI)定量参数之间的关系.方法:回顾性分析2016年10月至2018年10月于我院就诊的子宫内膜癌患者90...
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| 关 键 词： | 子宫内膜癌 分化 表观扩散系数 磁共振动态增强扫描成像 相关性 |
The relationship between apparent diffusion coefficient and DCE-MRI parameters in endometrial carcinoma with different degrees of differentiation |
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| ZHANG Ming,MENG Yingchun,ZHOU Yang. The relationship between apparent diffusion coefficient and DCE-MRI parameters in endometrial carcinoma with different degrees of differentiation[J]. Journal of Modern Oncology, 2021, 0(7): 1229-1233. DOI: DOI:10.3969/j.issn.1672-4992.2021.07.027 |
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| Authors: | ZHANG Ming MENG Yingchun ZHOU Yang |
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| Affiliation: | Radiology Department,Jingzhou Central Hospital,Hubei Jingzhou 434020,China. |
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| Abstract: | Objective:To investigate the relationship between apparent diffusion coefficient(ADC)and quantitative parameters of dynamic contrast enhanced MRI(DCE-MRI)in endometrial carcinoma with different degrees of differentiation.Methods:90 endometrial cancer patients in our hospital from October 2016 to October 2018 were retrospectively analyzed.According to the clinical pathology information,patients were divided into low-differentiation group(18 cases),medium-differentiation group(52 cases)and high-differentiation group(20 cases).DCE-MRI and diffusion weighted imaging(DWI)images of each group were analyzed,and the mean value of ADC as well as DCE-MRI related parameters Ktrans,Ve and Kep values were measured and further analyzed for their correlation.Results:ADC mean,K trans,Ve and Kep values were significantly different in endometrial carcinoma with degrees of different differentiation(P<0.05).ADC mean values in the medium-and low-differentiation groups were negatively correlated with Ktrans,Ve and Kep values(P<0.05),and the correlation enhanced along with the decrease of differentiation degree(r low,K trans=-0.612,r low,Ve=-1.313,r low,Kep=-0.568).Conclusion:There are significant differences in ADC mean,Ktrans,Ve and Kep indifferent differentiation endometrial carcinoma.ADC mean in the medium-and low-differentiation groups is negatively correlated with Ktrans,Ve and Kep.Moreover,the correlation is enhanced with the decrease of differentiation degree.These findings provide a basis for the preoperative differentiation grade diagnosis of endometrial cancer. |
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| Keywords: | endometrial carcinoma differentiation apparent diffusion coefficient dynamic contrast enhanced MRI correlation |
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